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Darvon Medical Research Studies

Up-to-date List of Darvon Medical Research Studies

What Research is Being Done?

A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two main types of clinical studies: clinical trials (also called interventional studies) and observational studies. Following list includes both interventional and observational studies.

Latest Darvon Medical Research Studies

Rank Status Study
1 Unknown  Neuraxial Pethidine After Lumbar Surgery Trial
Condition: Sciatica
Interventions: Drug: Pethidine;   Drug: Placebo
Outcome Measures: Cumulative 24-hour pethidine consumption;   Patient data:;   Age;   Gender;   Body mass index;   Current medications;   Preoperative opioid analgesic use (none, low, high - high dose being > 300 mg codeine or dextropropoxyphene daily or oral morphine or parenteral opioid use);   Compensable status (HNC, TAC, WCV or PMI/SUR) 22;   Surgical data:;   Anatomical extent of surgery (number of spinal levels);   Highest anatomical surgical level;   Experience level of primary surgeon (trainee or consultant);   Anatomical level of epidural tip (identified from postoperative X-Ray when taken as routine care only);   Dural tear at the time of surgery (yes/no);   Spinal instrumentation (yes/no);   Other end-points (all at 1, 4, 24 and 48 hours unless stated):;   Cumulative pethidine dose;   Cumulative morphine dose;   VAS scores for pain at rest and during movement;   Sedation score (1 - 4) 16;   VAS scores for nausea, pruritis;   Other adverse events: agitation, tremor, hallucinations, seizure;   Patient satisfaction scale for pain control during study (48 hours);   (very dissatisfied, dissatisfied, neutral, satisfied, very satisfied) 17;   Plasma pethidine and norpethidine levels (24 hours);   Physiotherapy assessment of ability to deep breathe & cough (unable, poor, adequate, good);   Length of inpatient stay

These studies may lead to new treatments and are adding insight into Darvon etiology and treatment.

A major focus of Darvon research is the development of new drugs and other treatment options. Studies seek to identify new drugs to treat various related disorders and to find safer, more effective doses for medications already being used. Other research is aimed at identifying receptors or drug targets.


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