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Death Medical Research Studies

Up-to-date List of Death Medical Research Studies

What Research is Being Done?

A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two main types of clinical studies: clinical trials (also called interventional studies) and observational studies. Following list includes both interventional and observational studies.

Latest Death Medical Research Studies

Rank Status Study
1 Recruiting Post Traumatic Stress Among Relatives of Brain-dead, Withdrawal of Life Support, and Sudden Death Patients
Condition: Stress Disorders, Post-Traumatic
Intervention: Other: IES-R and HDAS scores
Outcome Measures: IES-R > 37: yes/no;   IES-R;   HDAS score
2 Recruiting Comparative Evaluation of IRM and Autopsy in the Evaluation of Intra Uterine Fetal Death
Condition: Spontaneous Intra Uterine Fetal Death
Intervention: Other: Comparaison between MR and autopsy in the macroscopic evaluation of intra uterine Death.
Outcome Measures: Recognition of anatomic cerebral structures evaluated by a common grid.;   Recognition and mesurement of anatomic thoracic and abdominal structures by a common grid.;   Recognition and mesurement of the placenta and umbilical cord.;   Comparaison of quality criteria of both exams.
3 Recruiting Sudden Cardiac Death - Screening Of Risk Factors
Conditions: Sudden Cardiac Death;   Cardiomyopathies;   Channelopathies
Intervention: Other: ECG and survey screening
Outcome Measures: Type 1 electrocardiogram;   Clinical History - Red Flag;   all-cause mortality;   Cardiovascular Death
4 Not yet recruiting Study of Paced QRS Duration as a Marker of Sudden Cardiac Death
Condition: Sudden Cardiac Death
Intervention:
Outcome Measure: Sudden Cardiac Death
5 Recruiting Vest Prevention of Early Sudden Death Trial and VEST Registry
Conditions: Myocardial Infarction;   Ventricular Dysfunction;   Sudden Death;   Ventricular Tachycardia;   Ventricular Fibrillation
Intervention: Device: wearable defibrillator
Outcome Measures: Sudden Death mortality;   Cardiovascular, all-cause, and other cause specific mortality;   incidence of ventricular arrhythmias;   adverse events attributable to wearable defibrillator use;   compliance with wearable defibrillator use
6 Recruiting Imaging Techniques for Identifying Factors of Sudden Cardiac Death Risk
Condition: Sudden Cardiac Death
Intervention:
Outcome Measures: sudden cardiac Death;   cardiovascular Death;   appropriate ICD discharge;   composite sudden cardiac Death and appropriate ICD discharge;   heart failure admission
7 Recruiting Epidemiology of Sudden Death in Cameroon
Condition: Cardiovascular Diseases
Intervention:
Outcome Measure: Sudden Death, either cardiac or non-cardiac origin
8 Recruiting Inflammation, Cardiac Sympathetic Innervation, and Arrhythmic Sudden Death
Conditions: Ischemic Cardiomyopathy;   Dilated Cardiomyopathy;   Inflammation;   Sudden Cardiac Death
Intervention:
Outcome Measures: Determine if inflammation is associated with abnormal cardiac sympathetic innervation in patients enrolled in the PROSE-ICD study.;   Determine if inflammation, measured by IL-6, is associated with abnormal cardiac sympathetic innervation, measured by MIBG imaging;   Examine the combination of CRP and MIBG to predict ICD therapies in PROSE-ICD;   Compare several MIBG imaging metrics of sympathetic innervation, in addition to the late H/M ratio, including the early H/M ratio and the MIBG washout rate, in regards to their association with biomarkers of inflammation (CRP and IL-6).
9 Unknown  Do Pacifiers Protect From Sudden Infant Death Syndrome (SIDS) Through an Increase in Upper Airway Patency?
Condition: Sudden Infant Death
Intervention:
Outcome Measure: Upper airway caliber and patency
10 Recruiting Clinical Registry on Sudden Death Primary Prevention at Latin America
Conditions: Myocardial Infarction;   Sudden Death
Intervention: Procedure: Implantable Cardio Defibrillator (ICD),
Outcome Measures: Prevalence of patients with MADIT, MADIT II and MUST at Latin American countries;   Study incidence of Arrhythmic mortality and serious arrhythmic events, evaluated through remote monitoring
11 Recruiting Computed Tomography Angiography to Brain Death Assessment
Condition: Brain Death
Intervention:
Outcome Measure: Assess the presence or absence of contrast medium filling of the intracranial vessels in comatose patients.
12 Not yet recruiting Amiodarone Against ICD Therapy in Chagas Cardiomyopathy for Primary Prevention of Death
Conditions: Chagas Cardiomyopathy;   Non-sustained Ventricular Tachycardia;   At Least 10 Points in Rassi Risk Score for Death
Interventions: Procedure: ICD implantation;   Drug: amiodarone hydrochloride
Outcome Measures: all cause mortality;   Cardiac mortality;   Sudden cardiac Death;   Worsening heart failure warranting hospitalization;   Need for cardiac stimulation in the ICD arm;   Need for pacemaker implantation in the amiodarone therapy arm
13 Recruiting MAP-IDM: Identification of Molecular Markers of Sudden Death at the Acute Phase of Myocardial Infarction
Condition: Myocardial Infarction
Intervention: Genetic: Blood sample
Outcome Measure: Correlation phenotype/genotype of sudden Death at the acute phase of myocardial infarct.
14 Recruiting Using Ongoing Newborn Intervention Trials to Obtain Additional Data Critical to Maternal, Fetal and Newborn Health in a Harmonized Way
Conditions: Maternal Deaths;   Neonatal Deaths;   Still Births
Intervention: Other: This is an observational study being conducted as a substudy of antoher trial.
Outcome Measures: Burden of maternal and neonatal Death and still births;   Timing of maternal and neonatal Death and still births;   Causes of maternal and neonatal Death and still births
15 Recruiting Deceased Donor Biomarkers and Recipient Outcomes
Conditions: Deceased Donor Kidney Transplant;   Acute Kidney Injury;   Delayed Graft Function;   End Stage Renal Disease;   Graft Failure
Intervention:
Outcome Measures: Delayed Graft Function;   Death-Censored Graft Failure;   Graft Function
16 Unknown  Prospective Observational Study of the ICD in Sudden Cardiac Death Prevention
Conditions: Heart Failure, Congestive;   Death, Sudden, Cardiac;   Arrhythmia;   Cardiomyopathies
Intervention:
Outcome Measures: Arrhythmic Sudden Death defined as a shock from the ICD for rapid VT or VF or a ventricular arrhythmia not corrected by the ICD;   All cause mortality, CV mortality, heart transplant, ICD explantation
17 Recruiting Cardiac Rhythm Abnormalities in Patients With Refractory Epilepsy at High Risk for Sudden Death
Conditions: Refractory Epilepsy;   Arrhythmia;   Sudden Death
Intervention: Device: Medtronic REVEAL
Outcome Measure:
18 Recruiting Left Ventricular Structural Predictors of Sudden Cardiac Death
Conditions: Ischemic Cardiomyopathy;   Nonischemic Cardiomyopathy
Intervention:
Outcome Measures: Composite SCD outcomes;   Composite cardiac outcomes
19 Recruiting Adequate Definition of Delayed Graft Function in Living and Deceased Donor Kidney Transplantation
Conditions: Deceased Donor Kidney Transplantation;   Living Donor Kidney Transplantation
Intervention: Procedure: kidney transplantation, living or deceased donor
Outcome Measures: delayed graft function as defined by dialysis requirements within one week after transplantation;   delayed graft function as defined by urine output less than1200 ml during first day after transplantation;   delayed graft function as defined by serum creatinine decrease less than 10% during 48 hours after transplantation;   delayed graft function as defined by creatinine greater than 2.5 mg/dL at ten days after transplantation;   delayed graft function as defined by creatinine clearance less than 10 ml/min/1.73m2 during 24 hours after transplantation;   delayed graft function as defined by creatinine did not decrease less than preoperative value
20 Unknown  End-of-Life Fear in Patients With End-Stage Lung Disease (COPD)
Conditions: Chronic Obstructive Pulmonary Disease;   End-of-Life Fear;   Fear About Death and Dying;   Depression
Intervention: Behavioral: A brief psycho-educational intervention
Outcome Measures: Self-reported semi-structured interview about the fear of Death and dying, needs and wishes at the end-of-life in patients with severe COPD;   St. George's Respiratory Questionnaire (SGRQ);   Short Form Health Survey (Fragebogen zum allgemeinen Gesundheitszustand, SF-36);   Euroqol (EQ);   Patient Health Questionnaire (PHQ);   Hospital Anxiety and Depression Scale (HADS);   Borg Scale;   Diffusion capacity (DLCO);   Blood gas analysis (BGA);   Bodyplethysmographs;   Bio-Impedance-Analysis (BIA);   6-Minute Walk Distance (6 MWD);   Body Mass Index (BMI);   Blood tests;   Multidimensional assessment of attitudes toward Death and dying (Fragebogeninventar zur mehrdimensionalen Erfassung des Erlebens gegenüber Sterben und Tod, FIMEST);   COPD- Anxiety -Questionnaire (COPD-Angst-Fragebogen, CAF);   COPD- Disability- Index (CDI);   Differences in COPD admission rates, functional impairment, quality of life and end-of-life fear after treatment

These studies may lead to new treatments and are adding insight into Death etiology and treatment.

A major focus of Death research is the development of new drugs and other treatment options. Studies seek to identify new drugs to treat various related disorders and to find safer, more effective doses for medications already being used. Other research is aimed at identifying receptors or drug targets.


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