Deplin Research Studies

Up-to-date List of Deplin Medical Research Studies

What Research is Being Done?

A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two main types of clinical studies: clinical trials (also called interventional studies) and observational studies. Following list includes both interventional and observational studies.

Latest Deplin Medical Research Studies

1 Recruiting L-methylfolate Supplementation to OROS-Methylphenidate Pharmacotherapy in ADHD Adults
Condition: Attention Deficit Hyperactivity Disorder
Interventions: Drug: L-methylfolate;   Drug: OROS-Methylphenidate
Outcome Measure: Adult ADHD Investigator Symptom Rating Scale
2 Not yet recruiting The Role of Methylenetetrahydrofolate Reductase (MTHFR) and L-methylfolate in Depression
Condition: Depression
Intervention: Other: L-methylfolate
Outcome Measure: Hamilton Depression Rating Scale-24
3 Recruiting A Phase I/II Study of High-dose L-methylfolate in Combination With Temozolomide and Bevacizumab in Recurrent High Grade Glioma
Condition: Malignant Glioma
Interventions: Drug: Bevacizumab;   Drug: Temozolomide;   Dietary Supplement: Vitamin C
Outcome Measures: Maximum Tolerated Dose (Phase I);   Progression-free survival (Phase II);   Objective Response (Phase I);   Number of patients with each worst-grade toxicity. (Phase I);   Overall Survival (Phase II)

These studies may lead to new treatments and are adding insight into Deplin etiology and treatment.

A major focus of Deplin research is the development of new drugs and other treatment options. Studies seek to identify new drugs to treat various related disorders and to find safer, more effective doses for medications already being used. Other research is aimed at identifying receptors or drug targets.

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