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Desferoxamine Medical Research Studies

Up-to-date List of Desferoxamine Medical Research Studies

What Research is Being Done?

A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two main types of clinical studies: clinical trials (also called interventional studies) and observational studies. Following list includes both interventional and observational studies.

Latest Desferoxamine Medical Research Studies

Rank Status Study
1 Recruiting Safety and Efficacy of Deferasirox in Combination With Desferoxamine in β-thalassaemia Patients With Severe Cardiac Iron Overload
Conditions: Transfusion-dependent β-thalassemia Patients;   Cardiac Iron Overload
Interventions: Drug: Deferasirox;   Drug: Deferasirox + Deferoxamine
Outcome Measures: Number of patients achieving a complete response (CR);   Number of patients achieving a partial response (PR);   Number of patients with stable disease (SD;   Safety and tolerability will be measured by the number of post baseline adverse events (AEs) (clinical and laboratory abnormalities), severity and relationship to study i.e ocular/ auditory exams;   Reduction in cardiac iron overload of patients in intensive iron chelation therapy consisting of deferasirox-DFO and after transition to deferasirox monotherapy;   Time for a patient with severe cardiac iron receiving intensive deferasirox-DFO regimen to achieve a cardiac MRI T2* > 10 ms;   Reduction in Liver iron concentration (LIC);   Trends and associations between serum ferritin levels and LIC;   Improvement in cardiac function

These studies may lead to new treatments and are adding insight into Desferoxamine etiology and treatment.

A major focus of Desferoxamine research is the development of new drugs and other treatment options. Studies seek to identify new drugs to treat various related disorders and to find safer, more effective doses for medications already being used. Other research is aimed at identifying receptors or drug targets.


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