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Desogen Medical Research Studies

Up-to-date List of Desogen Medical Research Studies

What Research is Being Done?

A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two main types of clinical studies: clinical trials (also called interventional studies) and observational studies. Following list includes both interventional and observational studies.

Latest Desogen Medical Research Studies

Rank Status Study
1 Unknown  New Treatments for Troublesome Bleeding in Implanon Users
Condition: Menstrual Problem
Intervention: Drug: Marvelon
Outcome Measures: The number of days to stop bleeding after initiation of each treatment group and placebo;   The mean total number of bleeding and spotting days during the 90 day "treatment" reference period
2 Unknown  Continuous Versus Cyclic Use of Oral Contraceptive Pills in Adolescents
Condition: Contraception
Interventions: Drug: Desogestrel-Ethinyl Estradiol 21 tablets;   Drug: Desogestrel-Ethinyl Estradiol 28 tablets
Outcome Measures: The primary objective is to compare the compliance rates of adolescents who take OCPs continuously to those who take OCPs cyclically.;   The number of girls who have positive pregnancy test results at 12 months
3 Unknown  Evaluation of an Oral Contraceptive Containing 30 mg Ethinyloestradiol and 150 mg Desogestrel on Women's Health
Condition: Women With PMS
Intervention: Drug: Marvelon
Outcome Measures: serum Lipids;   PMS
4 Recruiting ProMRI PROVEN Master Study
Condition: Safety of MR (Magnetic Resonance) Conditional CRT-pacemakers and ICDs
Interventions: Device: ICD/CRT-P therapy;   Other: MRI
Outcome Measures: The Serious Adverse Device Effect (SADE) -free rate of the ICD/CRT-P system related to MRI;   Increase in atrial and ventricular pacing threshold(s) between pre-MRI and 1-month post-MRI;   Decrease in P-wave and R-wave amplitude (right and left) between pre-MRI and 1-month post-MRI.
5 Recruiting Fat Mediated Modulation of Reproductive and Endocrine Function in Young Athletes
Condition: Exercise-related Amenorrhea
Interventions: Drug: Transdermal 17Beta-estradiol, progesterone;   Drug: Ethinyl Estradiol + Desogestrel;   Dietary Supplement: Sham Comparator
Outcome Measures: Increase in bone density with transdermal estrogen versus oral estrogen or no estrogen in amenorrheic athletes;   Improvement in bone microarchitecture with transdermal estrogen versus oral estrogen or no estrogen in amenorrheic athletes
6 Recruiting Raltegravir Switch Study to Reduce Liver Fibrosis Progression in HIV-Hepatitis C Co-infection
Conditions: HIV;   Hepatitis C;   Liver Fibrosis
Interventions: Drug: Raltegravir;   Drug: Ritonavir-boosted protease inhibitor
Outcome Measures: To evaluate the effect of switch on change in liver fibrosis score;   To evaluate inflammatory markers associated with liver fibrosis;   To evaluate effect of switch on hepatic function;   To evaluate effect of switch on metabolic parameters;   Immunologic and virologic safety
7 Not yet recruiting Efficacy of PTX+IFN Alpha+ RBV on Hepatitis C Virus Coinfected HIV Patients
Conditions: Hepacivirus;   HIV Infections
Interventions: Drug: Pentoxifylline;   Drug: Placebo
Outcome Measures: sustained virologic rate 24 weeks post treatment with IFNalpha 2a/RBV/PTX with genotype 1 chronic HCV infection + HIV infection;   grade of hepatic fibrosis;   rapid virologic response (RVR) and extended rapid virologic response (eRVR) rates
8 Unknown  Therapeutic Effect of Desogestrel on Ventilatory Control in Patients With Congenital Central Hypoventilation Syndrome
Condition: Congenital Central Hypoventilation Syndrome
Intervention: Drug: Desogestrel
Outcome Measures: Minute ventilation;   Time to requirement of assisted ventilation
9 Recruiting Growth Hormone in Poor Responders to IVF Trial
Condition: Infertility
Interventions: Drug: Saizen (Human Growth Hormone);   Drug: No Saizen Control (Standard IVF Protocol)
Outcome Measures: Oocyte yield;   Pregnancy rate
10 Unknown  Minimal Stimulation Protocol Using Aromek(Letrozole) and Follitrope(recFSH) Combined With INVOCell-Low Cost IVF
Conditions: Primary Infertility;   Secondary Infertility;   Low Responders;   Mild to Moderate Male Factor Infertility
Interventions: Drug: Letrozole 2.5 mg, recFSH 75 IU;   Procedure: STEP-3: LH Suppression & Monitoring;   Procedure: STEP-4: HCG Timing;   Procedure: STEP-5: OPU, ET, Cancellation;   Procedure: INVOCell (Intravaginal Culturing)
Outcome Measures: Number of Follicles >15 mm on the day of HCG; Number of Oocytes aspirated; Fertilisation Rate;   Pregnancy Rate; Cost of Treatment

These studies may lead to new treatments and are adding insight into Desogen etiology and treatment.

A major focus of Desogen research is the development of new drugs and other treatment options. Studies seek to identify new drugs to treat various related disorders and to find safer, more effective doses for medications already being used. Other research is aimed at identifying receptors or drug targets.


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