Up-to-date List of Diabetes Medical Research Studies

What Research is Being Done?

A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two main types of clinical studies: clinical trials (also called interventional studies) and observational studies. Following list includes both interventional and observational studies.

Latest Diabetes Medical Research Studies

RankStatusStudy
1 Recruiting Diabetes and Partnership: Evaluation of a Diabetes Education Module
Condition: Diabetes Mellitus
Intervention: Behavioral: Education - Diabetes and Partnership
Outcome Measures: Change from baseline in Diabetes-specific empowerment on the adapted Diabetes Empowerment Scale at the 2-week and 6-month follow-up;   Change from baseline in problem-specific distress on the adapted Problem Areas in Diabetes (PAID) Scale at the 2-week and 6-month follow-up;   Change from baseline in glycemic control (HbA1c) at the 2-week and 6-month follow-up;   Change from baseline in health-related quality of life on the EQ-5D at the 2-week and 6-month follow-up;   Change from baseline in quality of life on the WHO-5 at the 2-week and 6-month follow-up;   Change from baseline in self-efficacy on the General Self-Efficacy Scale (GSE) the 2-week and 6-month follow-up;   Change from baseline in general Diabetes-distress at the 2-week and 6-month follow-up;   Change from baseline in depressive symptoms on the CES-D at the 2-week and 6-month follow-up
2 Recruiting Diabetes and Sports: Evaluation of a Diabetes Education Module
Condition: Diabetes Mellitus
Intervention: Behavioral: Education - Diabetes and Sports
Outcome Measures: Change from baseline in Diabetes-specific empowerment on the adapted Diabetes Empowerment Scale at the 2-week and 6-month follow-up;   Change from baseline in problem-specific distress on the adapted Problem Areas in Diabetes (PAID) Scale at the 2-week and 6-month follow-up;   Change from baseline in glycemic control (HbA1c) at the 2-week and 6-month follow-up;   Change from baseline in health-related quality of life on the EQ-5D at the 2-week and 6-month follow-up;   Change from baseline in physical activity on the International Physical Activity Questionnaire (IPAQ) at the 2-week and 6-month follow-up;   Change from baseline in quality of life on the WHO-5 at the 2-week and 6-month follow-up;   Change from baseline in self-efficacy on the General Self-Efficacy Scale (GSE) the 2-week and 6-month follow-up;   Change from baseline in general Diabetes-distress at the 2-week and 6-month follow-up;   Change from baseline in depressive symptoms on the CES-D at the 2-week and 6-month follow-up;   Change from baseline in hypoglycemia awareness at the 2-week and 6-month follow-up;   Change from baseline in self-care behaviors at the 2-week and 6-month follow-up
3 Recruiting Diabetes and Social Issues: Evaluation of a Diabetes Education Module
Condition: Diabetes Mellitus
Intervention: Behavioral: Education - Diabetes and Social Issues
Outcome Measures: Change from baseline in Diabetes-specific empowerment on the adapted Diabetes Empowerment Scale at the 2-week and 6-month follow-up;   Change from baseline in problem-specific distress on the adapted Problem Areas in Diabetes (PAID) Scale at the 2-week and 6-month follow-up;   Change from baseline in glycemic control (HbA1c) at the 2-week and 6-month follow-up;   Change from baseline in health-related quality of life on the EQ-5D at the 2-week and 6-month follow-up;   Change from baseline in quality of life on the WHO-5 at the 2-week and 6-month follow-up;   Change from baseline in self-efficacy on the General Self-Efficacy Scale (GSE) the 2-week and 6-month follow-up;   Change from baseline in general Diabetes-distress at the 2-week and 6-month follow-up;   Change from baseline in depressive symptoms on the CES-D at the 2-week and 6-month follow-up
4 Recruiting Diabetes and Travel: Evaluation of a Diabetes Education Module - a Randomized Controlled Trial (PRIMO_Travel)
Condition: Diabetes Mellitus
Intervention: Behavioral: Education - Diabetes and Travel
Outcome Measures: Change from baseline in Diabetes-specific empowerment on the adapted Diabetes Empowerment Scale at the 2-week and 6-month follow-up;   Change from baseline in problem-specific distress on the adapted Problem Areas in Diabetes (PAID) Scale at the 2-week and 6-month follow-up;   Change from baseline in glycemic control (HbA1c) at the 2-week and 6-month follow-up;   Change from baseline in health-related quality of life on the EQ-5D at the 2-week and 6-month follow-up;   Change from baseline in quality of life on the WHO-5 at the 2-week and 6-month follow-up;   Change from baseline in self-efficacy on the General Self-Efficacy Scale (GSE) the 2-week and 6-month follow-up;   Change from baseline in general Diabetes-distress at the 2-week and 6-month follow-up;   Change from baseline in depressive symptoms on the CES-D at the 2-week and 6-month follow-up
5 Recruiting Lifestyle Intervention for Treatment of Diabetes
Conditions: Type 2 Diabetes;   Overweight;   Obesity
Interventions: Behavioral: Community Lifestyle Weight Loss (LWL);   Behavioral: Diabetes Self Management (DSM)
Outcome Measures: Predicted Cardiovascular Risk;   Hemoglobin A1c;   Blood Pressure;   Lipids;   Weight Change
6 Recruiting Evaluation of a Stepped Care Approach to Manage Depression in Diabetes
Conditions: Major Depressive Disorder;   Minor Depressive Disorder;   Sub-Threshold Depression;   Diabetes Mellitus
Interventions: Behavioral: Step 1: Diabetes-Specific CBT (5 group sessions);   Behavioral: Step 2: Depression-Specific CBT (6 single sessions);   Behavioral: Step 3: Referral to Psychotherapist and/or Psychiatrist;   Behavioral: Standard Diabetes Education
Outcome Measures: Depressive Mood - Hamilton Rating Scale for Depression (HAMD);   Diabetes-Related Distress - The Problem Areas in Diabetes Questionnaire (PAID);   Psychological/ Emotional Well-Being - The WHO-5 Well-being Index (WHO-5);   Health-Related Quality of Life - The Short Form-36 Health Survey (SF-36);   Diabetes Self-Care Behavior - The Summary of Diabetes Self-Care Activities Measure (SDSCA);   Glycaemic Control (HbA1c);   Health-Related Quality of Life - The EuroQol-5D (EQ-5D);   Diabetes Self-Care Behavior - The Diabetes Self-Management Questionnaire (DSMQ)
7 Recruiting Changes in Mitochondrial Uncoupling Protein 2 (UCP2) Messenger RNA(mRNA) in Type 2 Diabetes (T2DM) Patients
Condition: Diabetes
Intervention: Procedure: Blood withdrawal
Outcome Measures: Levels of gene expression for UCP2 (RQ);   Improved metabolic state
8 Not yet recruiting Effectiveness Study of Interactive Web Application for Problem Solving in Diabetes Management
Condition: Diabetes Mellitus
Interventions: Behavioral: Early Mobile Diabetes Detective (MoDD);   Behavioral: Late Mobile Diabetes Detective (MoDD)
Outcome Measures: Change in HgA1c;   Change in Score on the Diabetes Problem-Solving Inventory (DPSI);   Change in Score on the Summary of Diabetes Self-Care Activities Questionnaire (SDSCA);   Change in Score on Problem Areas in Diabetes Scale (PAID); Change in Score on the Diabetes Self-Efficacy Scale (DSES);   Change in Score on the Patient Health Questionnaire-2 (PHQ-2);   Change in Fasting Blood Glucose Level;   Change in Total Cholesterol;   Change in Blood Pressure;   Change in High-Density Lipoprotein;   Change in Low-Density Lipoprotein
9 Recruiting Diabetes Care Management Compared to Standard Diabetes Care in Adolescents and Young Adults With Type 1 Diabetes
Condition: Type 1 Diabetes
Intervention: Other: Transition Coordinator
Outcome Measures: The proportion of subjects who fail to attend at least one outpatient adult endocrinology visit during the second year after transition to adult Diabetes care.;   In the 2 years of transfer to adult care-Frequency of A1C testing and mean levels Frequency of retinal exam microalbumin to creatinine ratio fasting lipid profile and foot exam testing Rate of hospitalization/ER visits for acute complications of Diabetes
10 Recruiting Non-Alcoholic Fatty Liver Disease in Gestational Diabetes
Condition: Gestational Diabetes Mellitus in Pregnancy
Interventions: Other: Subjects with Gestational Diabetes;   Other: Controls without Gestational Diabetes
Outcome Measures: Percentage of patients with NAFLD and gestational Diabetes.;   Insulin sensitivity expressed as the Matsuda Index, measured during an oral glucose tolerance test.
11 Not yet recruiting Web-Based Collaborative Care for Patients With Diabetes and Depression
Conditions: Diabetes Mellitus, Type 2;   Depression
Interventions: Device: web-based collaborative care;   Other: wait-list;   Behavioral: usual Diabetes outpatient care
Outcome Measures: Change in Patient Health Questionnaire-9 items (PHQ-9) score;   Change in biochemical index;   Chang in quality of life (EuroQol-5D)score;   Change in Diabetes-specific stress;   Change in Health behaviours;   Change in general self-efficacy
12 Unknown  Diabetes Support Project: Couples Intervention
Condition: Type 2 Diabetes
Interventions: Behavioral: Telephone support and behavior change;   Other: Diabetes self-management education
Outcome Measures: Blood glucose control (hemoglobin AIc);   Measures of behavior change (diet, physical activity);   Diabetes-related quality of life outcome (distress);   BMI/Waist circumference
13 Unknown  A Comprehensive Intervention for Diabetes and Comorbid Depression in Primary Care
Conditions: Type 2 Diabetes;   Major Depressive Disorder
Interventions: Behavioral: Diabetes and depression intervention;   Behavioral: Diabetes intervention
Outcome Measures: Glycosylated Hemoglobin;   Quick Inventory of Depressive Symptoms - Self Report
14 Unknown  Impact of a Diabetes Transitions Tool Kit on Post-Hospitalization Glycemic Control
Condition: Diabetes Mellitus, Type 2
Intervention: Other: Diabetes Transitions Tool Kit
Outcome Measures: Glycemic Control;   Diabetes Distress;   Diabetes Self-Management;   Unplanned Readmission or ED visit
15 Not yet recruiting Novel Model for South Asian Treatment in Diabetes (NaMaSTe-Diabetes) Trial in Primary Care
Condition: Type 2 Diabetes Mellitus
Intervention: Behavioral: Culturally tailored Diabetes program
Outcome Measures: Change in A1C or blood pressure (systolic or diastolic blood pressure);   change in fasting lipid profile;   Change in weight or waist circumference;   change in health status
16 Unknown  Parental Management of Young Children's Diabetes
Condition: Diabetes Mellitus, Type 1
Interventions: Behavioral: Parental Support;   Behavioral: Diabetes Education
Outcome Measures: Glycemic variability;   Parent Quality of Life;   Child Quality of Life;   Hemoglobin A1C
17 Unknown  Diabetes Mellitus Community Based Screening in Minority Populations
Conditions: Type II Diabetes;   Diabetes Mellitus
Interventions: Behavioral: Education on risk factors for Type II Diabetes;   Behavioral: Education on Type II Diabetes;   Behavioral: Education on regular visits to a Primary Care Provider
Outcome Measure:
18 Recruiting Together on Diabetes Study: Evaluation of a Pilot Diabetes Prevention and Management Program for American Indian Youth
Condition: Diabetes
Intervention: Behavioral: Together on Diabetes-Hopkins
Outcome Measures: Change in percent of total calories from fat from baseline through 12 months follow-up;   Increased physical activity levels between baseline and 12 months follow-up;   Decreased body mass index between baseline and 12 months follow-up;   Improvement in point of care Hemoglobin A1C level between baseline and 12 month follow-up;   Decrease in waist circumference between baseline and 12 months follow-up;   Decreased blood pressure between baseline and 12 months follow-up;   Improvements in youth Diabetes knowledge test score between baseline and 12 months follow-up;   Improved score on Pediatric quality of life assessment (Ped-QL) between baseline and 12 months follow-up;   Increased numbers of family members involved in Diabetes support care between baseline and 12 months follow-up;   Increased numbers of individuals having been screen for Diabetes between baseline and 12 months follow-up
19 Recruiting A Family-Based Diabetes Intervention for Hispanic Adults in an Emerging Community
Condition: Diabetes
Interventions: Behavioral: Experimental: Diabetes Self Management;   Behavioral: General Health Education
Outcome Measures: Hemoglobin A1C (HbA1C);   Behavioral outcomes of self-reported management of Diabetes;   Health-related quality of life;   Diabetes knowledge;   Family support;   Diabetes Self-efficacy
20 Recruiting Natural History Study of the Development of Type 1 Diabetes
Condition: Diabetes Mellitus, Type 1
Intervention:
Outcome Measures: Development of type 1 Diabetes;   Metabolic and Autoantibody Assessments

These studies may lead to new treatments and are adding insight into Diabetes etiology and treatment.

A major focus of Diabetes research is the development of new drugs and other treatment options. Studies seek to identify new drugs to treat various related disorders and to find safer, more effective doses for medications already being used. Other research is aimed at identifying receptors or drug targets.


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