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Diabetic Retinopathy Medical Research Studies

Up-to-date List of Diabetic Retinopathy Medical Research Studies

What Research is Being Done?

A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two main types of clinical studies: clinical trials (also called interventional studies) and observational studies. Following list includes both interventional and observational studies.

Latest Diabetic Retinopathy Medical Research Studies

Rank Status Study
1 Not yet recruiting Study of Effectiveness of Telemedicine in Identifying DIABETIC RETINOPATHY Cases
Condition: Diabetic Retinopathy
Interventions: Other: Tele-medicine;   Other: Conventional referral
Outcome Measures: Proportion of patients with confirmed DIABETIC RETINOPATHY (DR) diagnosed at the eye hospital;   The severity of diabetic retinopathy (DR);   The acceptance rate for referral in each arm;   Proportion of patients eligible for referral who had DR and who did not attend
2 Recruiting Panretinal Photo-stimulation in Proliferative DIABETIC RETINOPATHY
Condition: Severe Non-proliferative Diabetic Retinopathy
Interventions: Device: Green Pascal;   Device: Yellow Pascal
Outcome Measures: prevention on the developing of proliferative DIABETIC RETINOPATHY (assessed with slitlamp, color fundus, and fluorangiography);   regression of DIABETIC RETINOPATHY from Severe Non-Proliferative Stage (S-NPDR) to Moderate Non-Proliferative Stage (M-NPDR) or lesser severity of retinopathy;   reduction in visual acuity;   reduction in the field of vision;   reduction of central retinal thickness;   Pain assessment (questionnaire)
3 Unknown  Genetic Association of DIABETIC RETINOPATHY-1
Conditions: Diabetes;   Diabetic Retinopathy
Intervention:
Outcome Measures: The differences in the distribution of candidate genotypes and alleles between the study groups;   the frequencies of haplotypes of different single nucleotide polymorphisms
4 Not yet recruiting Evaluation of Progression of DIABETIC RETINOPATHY With Rapid Correction of Hyperglycemia
Condition: Diabetic Retinopathy
Intervention: Other: Initiation of treatment of diabetes
Outcome Measure: Progression of diabetic retinopathy
5 Not yet recruiting Prevalence of DIABETIC RETINOPATHY and Impact of Genetic Factors in the Development of DIABETIC RETINOPATHY of Patients With Type 1 and 2 Diabetes Mellitus in SlovaKia
Conditions: Diabetic Retinopathy;   Diabetic Macular Edema;   Diabetes Mellitus
Intervention: Genetic: Studied cohort
Outcome Measures: The prevalence of DIABETIC RETINOPATHY as the proportion of patients with DR (any stage) in a given subgroup according to DM duration;   Evaluate the prevalence and individual stages of DIABETIC RETINOPATHY in patients with type 1 and type 2 DM verified based on complex ophthalmologic measurements;   Evaluate the prevalence and individual stages of Diabetic Macular Edema (DME) in patients with type 1 and type 2 DM verified based on complex ophthalmologic measurements;   Evaluate the impact of risk factors on the prevalence of DIABETIC RETINOPATHY and Diabetic Macular Edema
6 Recruiting The Use of Alpha Lipoic Acid for the Treatment and Prevention of DIABETIC RETINOPATHY
Condition: Moderate Non-proliferative Diabetic Retinopathy
Intervention: Dietary Supplement: Alpha Lipoic Acid
Outcome Measures: Decreased progression of diabetic retinopathy.;   Changes in the plasma level of glutathione as measured by ELISA technique
7 Unknown  Propranolol for DIABETIC RETINOPATHY
Condition: Proliferative Diabetic Retinopathy
Intervention: Drug: Propranolol
Outcome Measures: Area of retinal neovascularization on fundus photography;   Retinopathy level in contralateral eye;   Optical coherence tomography macular thickness of treated and fellow eye;   Amount of fluorescein leakage on angiography;   Early Treatment DIABETIC RETINOPATHY Study visual acuity in study and fellow eye
8 Recruiting The Individually Marked Panretinal lasEr phoTokoagUlation for Proliferative DIABETIC RETINOPATHY Study - DETECT
Condition: Proliferative Diabetic Retinopathy
Intervention: Procedure: Panretinal laser photocoagulation
Outcome Measures: Proliferative DIABETIC RETINOPATHY progression/regression.;   Retinal vessel geometry (caliber, fractals and tortuosity)
9 Unknown  Trial of Yellow 577 nm Laser Versus Green 532 nm Laser for Proliferative DIABETIC RETINOPATHY
Condition: Proliferative Diabetic Retinopathy
Intervention: Procedure: Pan retinal photocoagulation laser treatment
Outcome Measures: Visual acuity measurement by logarithm of the minimum angle of resolution (logMAR);   Patient pain score during laser procedure
10 Recruiting Computer-based Screening for DIABETIC RETINOPATHY
Condition: Diabetic Retinopathy
Intervention:
Outcome Measures: Sensitivity and specificity of retinal screening for risk stratification of DR using digital fundus photographs with and without the assistance of the RiskAnalyzer.;   Sensitivity and specificity of retinal screening for risk stratification of DR using digital fundus photographs and the RiskAnalyzer
11 Unknown  Panretinal Photocoagulation for DIABETIC RETINOPATHY With PASCAL Laser
Condition: Diabetic Retinopathy
Intervention: Procedure: Panretinal photocoagulation
Outcome Measures: Incidence of severe visual loss after 1 year;   Clinical involution of retinal new vessels;   Nerve fiber layer thickness;   Retinal sensitivity
12 Recruiting Prevention of Macular Edema In Patients With DIABETIC RETINOPATHY Undergoing Cataract Surgery
Condition: Diabetic Retinopathy
Interventions: Drug: Aflibercept;   Drug: Sham
Outcome Measures: Safety and Efficacy;   Visual Acuity
13 Unknown  Bevacizumab as Adjunctive Treatment to Laser Panretinal Photocoagulation for Proliferative DIABETIC RETINOPATHY
Condition: Proliferative Diabetic Retinopathy
Interventions: Procedure: Panretinal photocoagulation;   Procedure: Procedure: Panretinal Photocoagulation (PRP) Drug: Intravitreous injection of Bevacizumab
Outcome Measures: Functional Macular Evaluation;   Structural Macular Evaluation
14 Unknown  Intravitreal Bevacizumab Vs Photocoagulation for Proliferative DIABETIC RETINOPATHY
Condition: Diabetic Retinopathy
Interventions: Drug: intravitreal injection of bevacizumab;   Procedure: panretinal photocoagulation
Outcome Measures: Best corrected visual acuity at six months and one year;   Macular thickness measured by OCT at six months and one year;   Median deviation in visual fields at one year;   Score on a patient satisfaction scale at six months and one year;   Complications associated to each treatment
15 Recruiting DIABETIC RETINOPATHY And the Myvisiontrack® (DRAMA) Study
Conditions: Diabetic Retinopathy;   Diabetic Macular Edema
Intervention: Device: Home vision monitoring using myVisionTrack®
Outcome Measures: Test efficacy of the test algorithm improvements;   Refine the decision rule;   Can improved testing algorithm minimize test time?;   Assess patient satisfaction with the test
16 Unknown  Evaluation of Ranibizumab in Proliferative DIABETIC RETINOPATHY (PDR) Requiring Vitrectomy
Condition: Proliferative Diabetic Retinopathy
Intervention: Drug: Lucentis (ranibizumab)
Outcome Measure: To evaluate the effect of ranibizumab on vitrectomy complications such as recurrent vitreous hemorrhage, postoperative retinal detachment rates, and development of intraoperative retinal breaks.
17 Recruiting Topic Ketorolac Added to Panphotocoagulation in Proliferative DIABETIC RETINOPATHY
Conditions: Proliferative Diabetic Retinopathy;   Macular Edema
Interventions: Drug: Ketorolac tromethamine;   Drug: Alcohol polivinilico
Outcome Measures: center subfield mean thickness using Stratus OCT measured in microns;   center point thickness using Stratus OCT, measured in microns;   macular volume using Stratus OCT, measured in cubic millimeters
18 Unknown  Intravitreal Bevacizumab for Management of Active Progressive Proliferative DIABETIC RETINOPATHY (PDR)
Condition: Diabetic Retinopathy
Intervention: Drug: bevacizumab
Outcome Measures: Regression of diabetic retinopathy;   visual acuity;   neovascularization;   fibrous proliferation;   traction retinal detachment;   vitreous hemorrhage;   pan retinal photocoagulation
19 Recruiting Analysis of Angiogenic Factor Levels in Eyes With DIABETIC RETINOPATHY
Condition: Diabetic Retinopathy
Intervention:
Outcome Measure: Aqueous secretory angiogenic and anti-angiogenic protein concentration
20 Unknown  The Effect of Intravitral Injection of Triamcinolone Combined With Cataract Surgery (Phacoemulsification) on Diabetic Macular Edema and DIABETIC RETINOPATHY
Condition: Diabetic Retinopathy
Intervention: Drug: Triamcinolone
Outcome Measures: Macula diameter;   Diabetic retinopathy

These studies may lead to new treatments and are adding insight into Diabetic Retinopathy etiology and treatment.

A major focus of Diabetic Retinopathy research is the development of new drugs and other treatment options. Studies seek to identify new drugs to treat various related disorders and to find safer, more effective doses for medications already being used. Other research is aimed at identifying receptors or drug targets.


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