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Diprosone Medical Research Studies

Up-to-date List of Diprosone Medical Research Studies

What Research is Being Done?

A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two main types of clinical studies: clinical trials (also called interventional studies) and observational studies. Following list includes both interventional and observational studies.

Latest Diprosone Medical Research Studies

Rank Status Study
1 Recruiting Evaluation of Efficacy and Safety of Epidural Steroid Injection Using Dexamethasone or Betamethasone
Condition: Spinal Pain
Interventions: Drug: Dexamethasone;   Drug: Betamethasone
Outcome Measures: rate of patients with pain improvement;   incidence of adverse events;   pain decrease
2 Unknown  Efficacy and Tolerability of Prednisolone Acetate 0.5% Cream Versus Betamethasone Valerate 0.1% Cream in Cortisosensitive Dermatosis
Conditions: Dermatitis, Atopic;   Dermatitis, Contact;   Dermatitis, Seborrheic;   Psoriasis
Interventions: Drug: 0.5% prednisolone acetate cream;   Drug: 0.1% betamethasone valerate cream
Outcome Measures: Evaluate efficacy and safety of 0.5% prednisolone cream in comparison to 0.1% betamethasone cream in the treatment of corticosensitive dermatosis.;   Evaluate physicians' and patients' perception of the efficacy and tolerability of treatment.
3 Recruiting Comparison of Effect of Postoperative Cyclosporine A 2% Ophthalmic Emulsion and Betamethasone Eye Drop on Surgical Success of Trabeculectomy Procedure
Condition: Glaucoma, Open Angle
Interventions: Drug: Cyclosporine;   Drug: Betamethasone
Outcome Measures: Intraocular Pressure (IOP);   Bleb morphology;   Subjective dry eye symptoms;   Surgical success rate;   Complications;   Visual acuity
4 Recruiting Betamethasone and Severity of Hyaline Membrane Disease
Condition: Pregnant Women Receive Celesten
Intervention:
Outcome Measures: Number of neonates with hyaline membrane disease;   Genetic polymorphisms;   mode of delivery;   blood sample of betamethasone;   Optimal dose of betamethasone;   gestational age;   birth weight;   sex;   Apgar score;   twinning;   time between birth and the last dose;   ethnicity;   maternal disease and treatment
5 Unknown  Efficacy and Safety of Betamethasone Microsphere in Patients With Diabetic Macular Edema (TSUBASA)
Condition: Diabetic Macular Edema
Interventions: Drug: Betamethasone Microsphere (DE-102) Low Dose;   Drug: Betamethasone Microsphere (DE-102) High Dose;   Drug: Sham
Outcome Measures: Best Corrected Visual Acuity(BCVA);   retinal thickness
6 Recruiting Efficacy and Safety of Betamethasone Microsphere in Patients With Macular Edema Following Branch Retinal Vein Occlusion (HIKARI)
Condition: Macular Edema Following Branch Retinal Vein Occlusion
Interventions: Drug: Betamethasone Microsphere (DE-102) Low Dose;   Drug: Betamethasone Microsphere (DE-102) High Dose;   Drug: Sham
Outcome Measures: Change from baseline of Best Corrected Visual Acuity(BCVA) in ETDRS letter score;   Change in retinal thickness from baseline
7 Not yet recruiting Comparison of Desloratadine Associated With Prednisolone (Tablet)Versus Dexchlorpheniramine Associated With Betamethasone (Tablet) for Adult Persistent Allergic Rhinitis Treatment
Condition: Allergic Rhinitis
Interventions: Drug: Desloratadine + Prednisolone;   Drug: Dexchlorpheniramine + Betamethasone
Outcome Measures: Efficacy of treatment in persistent allergic rhinitis based on nasal symptoms score;   Safety will be evaluated by the adverse events occurrences
8 Unknown  Comparison of 2 Doses of Corticosteroid Subacromial Injections for the Treatment of Painful Shoulder
Conditions: Tendonitis;   Bursitis
Interventions: Drug: Betamethasone Sodium Phosphate;   Drug: 1 cc - Betamethasone Sodium Phosphate;   Drug: 2 cc - Betamethasone Sodium Phosphate
Outcome Measure: constant score
9 Unknown  Nickel Desensitization Using Topical Therapy
Condition: Allergic Contact Dermatitis
Intervention: Drug: Calcipotriol, Betamethasone, Calcipotriol & Betamethasone
Outcome Measures: Change in contact dermatitis response to nickel allergen at 5 weeks after topical desensitization;   Change in immune cell profile of patients 5 weeks after nickel desensitization
10 Not yet recruiting Comparison of Desloratadine Associated With Prednisolone Oral Solution Versus Dexchlorpheniramine Associated With Betamethasone for Cutaneous Rash Treatment
Condition: Cutaneous Hypersensitivity
Interventions: Drug: Desloratadine + Prednisolone;   Drug: Dexchlorpheniramine + Betamethasone
Outcome Measures: Efficacy of treatment in acute cutaneous rash based on symptoms score;   Safety will be evaluated by the adverse event occurrences
11 Unknown  Efficacy of Micro-Pulse Steroid Therapy as Induction Therapy in Patients With Polymyalgia Rheumatica
Condition: Polymyalgia Rheumatica
Interventions: Drug: Betamethasone;   Drug: isotonic sodium chloride solution (placebo)
Outcome Measure: a total dose of glucocorticoids used in the course of the disease
12 Not yet recruiting Comparison of Desloratadine Associated With Prednisolone Oral Solution Versus Dexchlorpheniramine Associated With Betamethasone for Persistent Allergic Rhinitis Treatment
Condition: Allergic Rhinitis
Interventions: Drug: Dexchlorpheniramine + Betamethasone;   Drug: Desloratadine + Prednisolone
Outcome Measures: Efficacy of treatment in persistent allergic rhinitis based on nasal symptoms score;   Safety will be evaluated by the adverse events occurrences
13 Recruiting Caesarean and Corticotherapy
Condition: Neonatal Distress
Interventions: Drug: betamethasone;   Other: placebo
Outcome Measure: Neonatal respiratory distress
14 Not yet recruiting LEO 90100 Aerosol Foam Compared to Calcipotriol Plus Betamethasone Dipropionate Gel in Subjects With Psoriasis Vulgaris
Condition: Psoriasis Vulgaris (Plaque Psoriasis)
Interventions: Drug: LEO 90100 aerosol foam;   Drug: Aerosol foam vehicle;   Drug: Calcipotriol BDP gel;   Drug: Gel vehicle
Outcome Measure: Treatment success according to the PGA
15 Unknown  Impact of Antenatal Betamethasone on Plasma Glucose Levels
Condition: Hyperglycemia
Intervention:
Outcome Measure: Area under the curve of blood glucose
16 Not yet recruiting Effect of Antenatal Corticosteroids in Late Preterm
Condition: Late Preterm
Intervention: Drug: betamethasone
Outcome Measures: neonate respiratory distress syndrome;   1 and 5 minute Apgar scores, and complications during the first week of life, including hypoglycemia, seizures, intubation or medications
17 Not yet recruiting Facet Versus Trigger Point Injections for Chronic Neck Pain
Condition: Chronic Mechanical (Myofascial) Neck Pain
Interventions: Procedure: Betamethasone;   Procedure: Dexamethasone;   Procedure: Intramuscular Lidocaine;   Behavioral: Home Exercise
Outcome Measures: Patient Global Impression of Change (PGIC);   Pain Intensity Numeric Rating Scale;   Neck Disability Index;   Headache Impact Test - 6;   Patient Health Questionnaire - 9;   Adverse Events Checklist;   Global Cervical Active Range of Motion;   Mechanical (Pressure) Pain Threshold
18 Recruiting Antenatal Late Preterm Steroids (ALPS): A Randomized Placebo-Controlled Trial
Conditions: Pregnancy;   Respiratory Distress;   Pregnancy Outcome
Intervention: Drug: Corticosteroid
Outcome Measures: Composite Outcome;   Maternal outcomes;   Neonatal morbidity / mortality;   Respiratory Distress Syndrome;   Neonatal composite;   Need for immediate resuscitation after birth;   Surfactant use;   Chronic lung disease (BPD);   Necrotizing enterocolitis (NEC);   Morbidity composite;   Birth weight;   Hypoglycemia;   Hyperbilirubinemia;   Feeding difficulty;   Hypothermia;   Neonatal infectious morbidity;   Seizures / encephalopathy;   Length of hospital stay;   Number of and reason for infant re-hospitalizations, ER visits or unanticipated visits to the primary care pediatrician / specialist
19 Recruiting Ultrasound-guided Injection for DeQuervain's
Condition: DeQuervain's Tenosynovitis
Interventions: Drug: Betamethasone;   Device: Ultrasound
Outcome Measures: DASH - "Disabilities of the Arm, Shoulder, and Hand" Score At baseline, and change from baseline at 6-8 weeks, 12-16 weeks;   Pain Scores on the Visual Analogue Scale (VAS)
20 Recruiting Corneal Epithelium Repair and Therapy Using Autologous Limbal Stem Cell Transplantation
Conditions: Corneal Disease;   Pterygium;   Myopia;   Hyperopia
Interventions: Procedure: LSCs and amniotic membrane (Modified Technique);   Procedure: Amniotic membrane only (Traditional Technique);   Procedure: PRK, LSCs, and amniotic membrane (Modified Technique);   Procedure: PRK only (Traditional Technique);   Drug: Levofloxacin;   Drug: Betamethasone;   Drug: Limbal stem cells (LSCs)
Outcome Measures: Composite measure of visual function in eyes treated for corneal ocular surface disease.;   Composite measure of visual function in eyes after photo-refractive keratectomy (PRK);   Incidence of transparency of the cornea

These studies may lead to new treatments and are adding insight into Diprosone etiology and treatment.

A major focus of Diprosone research is the development of new drugs and other treatment options. Studies seek to identify new drugs to treat various related disorders and to find safer, more effective doses for medications already being used. Other research is aimed at identifying receptors or drug targets.


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