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Dipyridamole Medical Research Studies

Up-to-date List of Dipyridamole Medical Research Studies

What Research is Being Done?

A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two main types of clinical studies: clinical trials (also called interventional studies) and observational studies. Following list includes both interventional and observational studies.

Latest Dipyridamole Medical Research Studies

Rank Status Study
1 Not yet recruiting Dipyridamole for Immune Activation in HIV
Condition: HIV Infection
Interventions: Drug: Dipyridamole;   Drug: Placebo, then Dipyridamole
Outcome Measures: Change in plasma levels of immune activation inflammatory markers;   Adverse events, discontinuations of study drug;   Correlation of plasma Dipyridamole level to markers of immune activation and inflammation
2 Recruiting Dipyridamole Assessment for Flare Reduction in Systemic Lupus Erythematosus (SLE)
Condition: Systemic Lupus Erythematosus
Interventions: Drug: extended release Dipyridamole 200mg/aspirin 25mg;   Drug: 81mg aspirin
Outcome Measures: British Isles Lupus Assessment Group Responder Index (BICLA);   Time to first flare;   Systemic Responder Index (SRI) 4/5;   Health related quality of life [Lupus Quality of Life (Lupus QoL), Short Form 36v2];   Fatigue (FACIT-fatigue score);   Sleep quality [Pittsburgh Sleep Quality Index (PSQI)];   Depression [Center for Epidemiologic Studies Depression (CES-D) Scale];   Number of Participants with Adverse Events as a Measure of Safety and Tolerability;   SRI component analyses;   Cutaneous Lupus Disease Area and Severity Index (CLASI)
3 Recruiting Phase II Study for the Diagnosis and Functional Assessment of CAD Using Transthoracic-Echodoppler
Condition: Ischemic Heart Disease
Intervention: Drug: adenosine + Dipyridamole
Outcome Measures: Diastolic mean and peak coronary blood velocities;   Incidence rate and severity of adverse events, in particular, chest pain, dyspnoea, hypotension, bradycardia, AV blocks, arrhythmia.
4 Unknown  "Normal Coronary Artery" With Slow Flow Improved by Adenosine Injection, Dipyridamole Treatment and Clinical Follow-up
Condition: Coronary Angiography
Interventions: Drug: Statin, aspirin;   Drug: Dipyridamole
Outcome Measure: Alleviation of chest pain
5 Recruiting Effect of Ticagrelor vs. Dipyridamole on Adenosine Uptake
Condition: Coronary Artery Disease
Intervention: Drug: Adenosine
Outcome Measure: Interstitial levels of adenosine
6 Recruiting Treatment of Supine Hypertension in Autonomic Failure
Condition: Hypertension
Interventions: Drug: Clonidine;   Drug: Nitroglycerin transdermal;   Drug: Dipyridamole/ Aspirin (Aggrenox);   Drug: Desmopressin (DDAVP);   Drug: Sildenafil;   Drug: Nifedipine;   Drug: Hydralazine;   Drug: Hydrochlorothiazide;   Drug: Placebo;   Drug: Bosentan;   Drug: Diltiazem;   Drug: Eplerenone;   Drug: guanfacine;   Dietary Supplement: L-arginine;   Drug: captopril;   Drug: carbidopa;   Drug: losartan;   Drug: metoprolol tartrate;   Drug: nebivolol hydrochloride;   Drug: prazosin hydrochloride;   Drug: tamsulosin hydrochloride;   Other: Head-up tilt.;   Drug: aliskiren;   Other: Local heat stress
Outcome Measures: Decrease in supine systolic blood pressure;   Decrease in pressure natriuresis
7 Recruiting Patent Foramen Ovale Closure or Anticoagulants Versus Antiplatelet Therapy to Prevent Stroke Recurrence
Conditions: Ischemic Stroke;   Patent Foramen Ovale;   Atrial Septal Aneurysm;   Migraine
Interventions: Drug: aspirin;   Drug: Antivitamins K;   Device: Devices for PFO closure
Outcome Measures: stroke(fatal or not);   Disabling stroke;   Ischemic stroke;   Cerebral haemorrhage;   Ischemic stroke, TIA, or systemic embolism;   Death (all causes);   Vascular death;   Moderate to severe bleeding complications;   Procedural or device complications
8 Unknown  Adenosine Activity in Producing Venoarteriolar Reflexes
Condition: Venoarteriolar Reflex
Intervention: Drug: aminophylline
Outcome Measure: To study whether increasing ore blocking adenosine activity changes arteriolar blood flow in the limb.
9 Recruiting Triple Antiplatelets for Reducing Dependency After Ischaemic Stroke
Condition: Stroke
Intervention: Drug: Aspirin, Dipyradimole, Clopidogrel
Outcome Measures: The primary outcome is ordinal stroke severity at 90 days;   Safety;   Serious adverse events;   Death;   Platelet function.
10 Unknown  The Association of Endothelial Dysfunction and Cardiac Allograft Vasculopathy
Condition: Heart Transplantation
Intervention:
Outcome Measure:
11 Recruiting Technical Development of Cardiovascular Magnetic Resonance Imaging
Condition: Cardiovascular Disease
Intervention:
Outcome Measures: The overall objective of this protocol is to test and develop innovative new noninvasive MRI techniques suitable for evaluating patients with cardiovascular disease.;   Technical Development of Multiecho MRI Methods;   Technical Developments Related to Distinguishing Fat and Water by MRI
12 Recruiting Comparison of Rubidium PET and SPECT With CZT Crystals for Detection of Myocardial Ischemia in Overweighed Patients and Women
Condition: Myocardial Ischemia
Intervention: Radiation: Rubidium PET
Outcome Measures: Myocardial ischemia;   Size and intensity of myocardial ischemia
13 Recruiting Multi-modality Imaging of Ischemia With 18F-FDG PET and CTA
Condition: Myocardial Ischemia
Intervention: Radiation: PET MPI imaging with 18F-Fluorodeoxyglucose
Outcome Measures: Extent of ischemia as determined by visual and quantitative analysis;   The degree of correlation between the multiple modalities (CTAm stress PET or SPECT and 18FDG PET)
14 Unknown  Evaluation of Integrated Cardiac Imaging in Ischemic Heart Disease
Condition: Ischemic Heart Disease
Interventions: Other: Invasive coronary angiography;   Other: Stress imaging
Outcome Measures: Diagnostic algorithm for IHD;   Cost-benefit and cost-effectiveness analysis

These studies may lead to new treatments and are adding insight into Dipyridamole etiology and treatment.

A major focus of Dipyridamole research is the development of new drugs and other treatment options. Studies seek to identify new drugs to treat various related disorders and to find safer, more effective doses for medications already being used. Other research is aimed at identifying receptors or drug targets.


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