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Dulcolax Medical Research Studies

Up-to-date List of Dulcolax Medical Research Studies

What Research is Being Done?

A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two main types of clinical studies: clinical trials (also called interventional studies) and observational studies. Following list includes both interventional and observational studies.

Latest Dulcolax Medical Research Studies

Rank Status Study
1 Recruiting Comparison Between 2L Coolprep® and Combination of 1L Coolprep® and Bisacodyl as Bowel Preparation
Conditions: Healthy Person;   Bowel Preparation Before Colonoscopy
Interventions: Drug: 2L Coolprep®;   Drug: 1L Coolprep® and Bisacodyl
Outcome Measures: Bowel cleansing scale;   Bowel cleansing scale of Right/Transverse/Left colon
2 Recruiting Efficacy and Safety of Bisacodyl and Lactulose as a Preparation for Colonoscopy
Condition: Colonoscopy Preparation
Intervention: Drug: Bisacodyl and Lactulose
Outcome Measures: Efficacy of bisacodyl and lactulose as a preparation for colonoscopy.;   Safety of bisacodyl and lactulose as a bowel evacuant;   Tolerability of and preference for bisacodyl and lactulose as a bowel evacuant
3 Recruiting Efficacy of 2-Liter Mixed Preparation With Bisacodyl Plus Polyethylene Glycol and 4-Liter Polyethylene Glycol for Colon Cleansing in Patients With Prior History of Colorectal Resection
Condition: Intestinal Cancer
Interventions: Drug: Polyethylene glycol;   Drug: Bisacodyl
Outcome Measures: quality of bowel preparation rated according to a modified Ottawa bowel preparation scale;   Tolerability to the preparation (specific questionaire);   safety (adverse event rate);   Lesion detection (type and lesion detection rate/patient)
4 Unknown  Comparison of Bowel Cleansing Methods for Colonoscopy in Hospitalized Patients
Condition: Intestine; Complaints
Intervention:
Outcome Measures: The efficacy of bowel preparation;   Patient's compliance and acceptability;   Patient's compliance and acceptability (2);   Patient's compliance and acceptability (3)
5 Recruiting A Prospective, Randomized Controlled Clinical Study of the Efficacy and Safety of Bowklean and Klean-Prep With Dulcolax for the Bowel Preparation Prior Colonoscopy
Condition: Bowel Preparation Before Colonoscopy
Intervention: Drug: Picosulfate sodium, magnesium oxide, citric acid
Outcome Measures: The percentage of subjects that achieve excellent or good cleansing (success rate) in the Aronchick Scale.;   Proportion of successes (excellent, good, or fair) by individual colon segment (ascending, transverse, descending), which are assessed with the Ottawa scale.
6 Recruiting Methylnaltrexone Use for Opioid-induced Postoperative Constipation
Condition: Constipation
Interventions: Drug: Methylnaltrexone;   Drug: Senna, docusate sodium, bisacodyl, magnesium hydroxide, Miralax
Outcome Measures: reduction of post-operative opioid induced constipation;   time to ambulation in post-operative pediatric spinal fusion patients
7 Not yet recruiting Comparison of Two Types of Bowel Preparation for Inpatient Colonoscopy
Condition: Hospitalized Patients
Interventions: Drug: PEG/electrolytes 2L/2L split dose;   Drug: Bisacodyl 15 mg and PEG/electrolytes 1L/1L split dose
Outcome Measures: Efficacy;   Tolerability;   Clinical quality standards;   Cecal/ileal intubation rate;   Polyp detection rate
8 Recruiting 2L Oral Bi-PegLyte Versus 2L Oral MoviPrep Regimen for Outpatient Colonic Preparation
Condition: Colonoscopy
Interventions: Drug: Polyethylene Glycol (PEG) and 15 mg Bisacodyl;   Drug: Polyethylene Glycol (PEG) + ascorbic acid
Outcome Measures: Bowel cleansing efficacy as rated by a Boston Bowel Preparation Scale score of greater than 8;   Patient tolerability to each 2L product
9 Not yet recruiting Multidisciplinary Approach Versus Conventional Approach in Colonic Preparation of Hospitalized Patients
Condition: Bowel Preparation for Colonoscopy
Interventions: Behavioral: Education;   Other: Fiber free diet;   Dietary Supplement: Adjuvants;   Drug: Polyethylene glycol (PEG);   Drug: Bisacodyl
Outcome Measures: percentage of patients with adequate bowel preparation;   Percentage of patients with adequate bowel preparation by bowel segments;   Tolerance to the colonoscopy;   Percentage of complete/incomplete colonoscopies and reprogramming;   Complications during and after the procedure;   Doses of sedation needed during the colonoscopy;   Tolerance to the preparation;   Endoscopic findings
10 Unknown  Study of Efficacy and Tolerability of Various Bowel Preps in Diabetic Patients
Condition: Diabetes Mellitus
Interventions: Drug: Golytely (polyethylene glycol electrolyte lavage solution) and placebo;   Drug: split dose of Golytely (polyethylene glycol electrolyte lavage solution) + placebo;   Drug: split dose of Golytely (polyethylene glycol electrolyte lavage solution) and bisacodyl
Outcome Measures: Measure the % of participants with effective (how well the colon is cleansed using the validated Boston Bowel Preparation Scale) for various bowel preparations for colonoscopy.;   Measure of patients who develop (tolerance)side effects of taking bowel preparations.
11 Recruiting Colonoscopy Preparation Optimization for INpatients- COIN Study
Conditions: Endoscopy;   Bowel Preparation Solutions
Interventions: Drug: Bisacodyl 10mg;   Drug: Polyethelene Glycol;   Drug: Picosulfate sodium
Outcome Measures: Ottawa Bowel Prep Score;   Procedures Cancelled or repeated due to inadequate bowel preparation;   Individual Components of Ottawa Bowel Prep Score;   Adverse Effects;   Tolerability of the preparation
12 Recruiting Different Bowel Preparations for Colonoscopy In Children
Condition: Colonoscopy
Interventions: Device: PEG-4000 with citrates and simethicone;   Device: polyethylene glycol 4000 solution with simethicon;   Device: polyethylene glycol 3350 hyper-osmotic solution with ascorbic acid;   Device: sodium picosulphate plus magnesium oxide and citric acid
Outcome Measures: Efficacy;   safety;   clinical tolerabiity;   Compliance;   Acceptability
13 Recruiting Evaluation of Proposed EZ2go Complete Bowel Cleansing System
Conditions: Screening Colonoscopy;   Surveillance Colonoscopy;   Colonoscopy
Interventions: Other: Ez2go Complete;   Other: LoSo Prep
Outcome Measures: Measurement of Efficacy;   Evaluate the safety
14 Unknown  Efficacy and Safety of Polyethylene Glycol Compared With Sodium Picosulphate for Bowel Preparation Before Colonoscopy
Condition: Bowel Preparation
Interventions: Drug: Sodium Picosulphate;   Drug: Polyethylene Glycol
Outcome Measures: Percentage of patients requiring repeat colonoscopy because of poor preparation;   Patient's satisfaction as measured by questionnaire and willingness to repeat same preparation on future examination
15 Not yet recruiting Colon Cleansing Quality of Polyethylene Glycol Compared With Polyethylene Glycol Plus Ascorbic Acid.
Condition: Colonoscopy Preparation
Interventions: Drug: Polyethylene glycol 4000;   Drug: Macrogol 3350 plus ascorbic acid
Outcome Measures: Colon cleansing;   Tolerance of bowel preparation;   Detection of colorectal neoplasia
16 Unknown  Individual Approach for Bowel Preparation Before Colonoscopy
Conditions: Split-dose Bowel Preparation;   Polyethylene Glycol Solution;   Risk Factors Inadequate Preparation
Intervention: Other: individual preparation for colonoscopy
Outcome Measures: the index of preparation quality for the whole colon;   compliance safety

These studies may lead to new treatments and are adding insight into Dulcolax etiology and treatment.

A major focus of Dulcolax research is the development of new drugs and other treatment options. Studies seek to identify new drugs to treat various related disorders and to find safer, more effective doses for medications already being used. Other research is aimed at identifying receptors or drug targets.


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