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Dysphagia Medical Research Studies

Up-to-date List of Dysphagia Medical Research Studies

What Research is Being Done?

A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two main types of clinical studies: clinical trials (also called interventional studies) and observational studies. Following list includes both interventional and observational studies.

Latest Dysphagia Medical Research Studies

Rank Status Study
1 Unknown  Dysphagia in Oculopharyngeal Muscular Dystrophy (OPMD)- Evaluation, Endoscopic Examination of Swallowing, Treatment and Long Term Follow up
Condition: Dysphagia
Intervention: Procedure: Upper esophageal sphincter myotomy
Outcome Measure: Dysphagia, quality of life. Proper intervention timing in OPMD based on knowledge about the natural history of the feeding difficulty.
2 Recruiting Functional Endoscopy in Neurogenic Dysphagia
Condition: Neurogenic Dysphagia
Intervention: Procedure: transnasal functional endoscopy
Outcome Measures: Number of patients in which the procedure may be successfully performed (feasibility);   Pathologic endoscopic findings in patients suffering from neurogenic Dysphagia;   Number of patients with adverse events as a measure of safety and tolerability
3 Unknown  Optimal Management of Malignant Dysphagia
Conditions: Malignant Dysphagia;   Esophageal Cancer
Interventions: Radiation: Brachytherapy;   Procedure: Stent insertion
Outcome Measure: To investigate the change in Dysphagia score (0-4 Likert scale) measured at baseline and at 10 weeks
4 Not yet recruiting Evaluation of Transcutaneous Electrical Stimulation in Post Stroke Dysphagia
Conditions: Oropharyngeal Dysphagia;   Deglutition Disorders
Intervention: Device: Urostim I stimulation
Outcome Measure: Evaluation of oropharyngeal Dysphagia symptoms
5 Recruiting The Effect of Repetitive Transcranial Magnetic Stimulation for Poststroke Dysphagia Recovery
Conditions: Stroke;   Dysphagia
Intervention: Device: rTMS, Magstim Rapid2
Outcome Measures: Dysphagia severity on Aus TOMs swallowing score;   Imaging evidence with video-esophagography
6 Recruiting Neuromuscular Electrical Stimulation (NMES) for Dysphagia in Neonates
Condition: Dysphagia
Interventions: Device: VitalStim;   Device: Sham VitalStim
Outcome Measures: Reduction in G-tube rate insertions for the treatment grouped compared to the sham group.;   Increased percent of subjects towards achieving full oral feedings earlier in the subject's Dysphagia treatment.;   Increase the amount of formula volume taken at feedings from beginning to end of study.;   Earlier NG tube removal for the treatment group compared to the control group.;   Improve swallowing skills as measured by videofluoroscopic swallowing study (VFSS) and the video swallow assessment worksheet.;   Decrease spells with oral feeds over the course of the study.;   Allow for healthy weight gain via improved feedings.;   Increase the caloric intake orally.;   Decrease the oxygen requirement before and after study.;   Decrease inpatient length of stay.
7 Unknown  Comparison of Ultrasound and Videofluoroscopic Imaging Techniques in Diagnosing Dysphagia in Stroke Patients
Condition: Dysphagia
Intervention: Other: No intervention
Outcome Measure:
8 Recruiting EoE(Eosinophilic Esophagitis)
Conditions: Eosinophilic Esophagitis;   Dysphagia
Intervention: Procedure: Eosinophilic Esophagitis with Dysphagia
Outcome Measure: Evaluation of quantitative MRI as a diagnostic option for eosinophilic esophagitis
9 Recruiting Identifying and Treating Arousal Related Deficits in Neglect and Dysphagia
Conditions: Neglect;   Dysphagia
Interventions: Drug: Modafinil;   Drug: Placebo
Outcome Measures: Predicting response to modafinil among subjects with neglect;   Predicting response to modafinil among subjects with Dysphagia
10 Unknown  Routine Screening for Eosinophilic Esophagitis in Patients Presenting With Dysphagia
Condition: Dysphagia
Outcome Measure:
11 Recruiting Transcranial Direct Current Stimulation for Dysphagia Therapy in Acute Stroke Patients
Conditions: Stroke;   Dysphagia
Interventions: Device: Transcranial direct current stimulation;   Device: Sham stimulation
Outcome Measures: FEDSS (Fiberoptic Endoscopic Dysphagia Severity Scale) Score;   Diet at discharge;   Dysphagia Severity Rating Score;   Endoscopically assessed swallow function
12 Unknown  Reducing Dysphagia Associated With Anterior Cervical Spine Surgery by Maintaining Low Endotracheal Tube Cuff Pressure
Condition: Deglutition Disorders
Interventions: Procedure: Maintaining low (15mmHg) ETT cuff pressure;   Procedure: Maintaining a normal pressure in the ETT cuff
Outcome Measures: Severity of Dysphagia;   Overall health score;   Percentage change in anterior cervical soft-tissue thickness on plain lateral radiographs;   Cost-effectiveness
13 Recruiting Dysphagia and Pneumonia
Conditions: Dysphagia;   Pneumonia
Intervention: Other: Modified diet
Outcome Measures: Rehospitalization;   Mortality rate
14 Recruiting Tongue Pressure Profile Training for Dysphagia Post Stroke
Condition: Dysphagia
Interventions: Behavioral: Tongue Pressure Profile Training;   Behavioral: Tongue-Pressure Strength-and-Accuracy Training
Outcome Measures: Change in Swallow Response Time for 5 cc thin liquid swallows;   Penetration-Aspiration Scale score for 5 cc thin liquid swallows;   Changes in tongue-palate pressure amplitude for maximum isometric pressures
15 Unknown  Pediatric Dysphagia Outcomes After Injection Laryngoplasty for Type I Laryngeal Cleft
Conditions: Dysphagia;   Aspiration;   Quality of Life
Intervention: Procedure: Injection laryngoplasty
Outcome Measure: Change in quality of life
16 Not yet recruiting Swallowing and Breathing Exercises for Dysphagia in Parkinson Disease
Conditions: Parkinson Disease;   Dysphagia
Interventions: Other: Swallowing exercise;   Other: Breathing Exercises;   Other: Swallowing and breathing exercises
Outcome Measures: Swallowing dynamics;   Vocal and speech measures;   Breathing measures
17 Recruiting Comparison Study of Brachytherapy and Endoscopic Stenting for Dysphagia in Esophago-Gastric Junction Cancer
Condition: Adenocarcinoma of the Esophago-gastric Junction
Interventions: Radiation: Brachytherapy;   Procedure: Endoscopic stenting
Outcome Measures: The highest improvement of Dysphagia grade;   Time to the best swallowing improvement;   Time to recurrent worsening of swallowing;   The highest improvement of stricture diameter;   the procedure related morbidity;   the procedure related mortality;   The frequency of Dysphagia related additional endoscopic interventions;   Overall survival;   Quality of life
18 Recruiting Quality of Life and Dysphagia Following Palliative Stenting in Esophageal Cancer
Condition: Esophageal Cancer
Outcome Measures: improvement of Dysphagia post stenting;   Quality of life post stenting
19 Recruiting Efficacy of Two Interventions Increasing Sensory Stimulus in Elderly Patients With Oropharyngeal Dysphagia
Condition: Dysphagia
Interventions: Device: Transcutaneous electrical stimulation;   Dietary Supplement: TRPV1 agonist
Outcome Measures: Oropharyngeal motor response measured by Videofluoroscopy.;   Cortical activation measured by electroencephalography.
20 Unknown  Testing of a New Scale Measuring Medical Outcomes of Dysphagia (MOD) in Adult Patients With Swallowing Disorders
Condition: Dysphagia
Outcome Measures: Reliability of the MOD subscales;   Validity of the MOD subscales

These studies may lead to new treatments and are adding insight into Dysphagia etiology and treatment.

A major focus of Dysphagia research is the development of new drugs and other treatment options. Studies seek to identify new drugs to treat various related disorders and to find safer, more effective doses for medications already being used. Other research is aimed at identifying receptors or drug targets.

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