Up-to-date List of Ethyol Medical Research Studies

What Research is Being Done?

A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two main types of clinical studies: clinical trials (also called interventional studies) and observational studies. Following list includes both interventional and observational studies.

Latest Ethyol Medical Research Studies

1 Recruiting A Phase II Clinical Trial on Comparison of Effectiveness and Safeness of Different Amifostine Regimens
Conditions: Nasopharyngeal Neoplasms;   Salivary Gland Diseases;   Bone Marrow Diseases;   Mucositis
Interventions: Drug: Amifostine every-other-day regimen;   Drug: Amifostine everyday regimen
Outcome Measures: Effect on improving myelosuppression;   Effect on improving xerostomia;   Effect on improving mucositis;   Effect on improving Quality of Life (QOL).;   Effect on improving Karnofsky Performance Scores (KPS);   Incidence and severity of Nausea;   Incidence and severity of Vomiting;   Incidence and severity of Hypotension;   Incidence and severity of Hypocalcemia
2 Recruiting A Phase II Study of Amifostine for the Prevention of Acute Radiation-Induced Rectal Toxicity
Condition: Rectal Cancer
Intervention: Drug: Amifostine
Outcome Measure: Acute radiation-induced toxicity: daily diarrhea frequency
3 Not yet recruiting Hyperthermic Thoracic Perfusion (HITEC) for Children, Adolescents and Adults With Sarcomas
Condition: Lung Cancer
Interventions: Drug: Cisplatin;   Drug: Amifostine
Outcome Measures: Maximum Tolerated Dose (MTD) of Hyperthermic Intrathoracic Pleural Chemotherapy (HITC);   Time to Relapse
4 Recruiting A Study of Amifostine for Prevention of Facial Numbness in Radiosurgery Treatment of Trigeminal Neuralgia
Condition: Trigeminal Neuralgia
Interventions: Drug: Amifostine;   Procedure: CyberKnife stereotactic radiosurgery
Outcome Measures: Facial numbness following radiosurgery;   Pain relief following radiosurgery
5 Recruiting Total Skeletal Irradiation in Multiple Myeloma Before Second Autologous Hematopoietic Stem Cell Transplantation
Condition: Multiple Myeloma
Intervention: Radiation: Total Skeletal Irradiation
Outcome Measures: Define the maximum tolerated dose of a derived high dose therapy regimen;   Determine the dose-limiting toxicity (DLT) of TSI-HT therapy;   Compare toxicities to those produced by the AHSCT1 regimen;   Compare antitumor results obtained by TSI-HT before AHSCT
6 Unknown  Oral Selenium Therapy for the Prevention of Mucositis
Conditions: Mucositis;   Hematopoietic Stem Cell Transplantation
Interventions: Drug: Oral selenium;   Drug: Oral placebo
Outcome Measures: The grade of oral mucositis after bone marrow transplantation;   Evaluation of selenium concentration and glutathione peroxidase level in serum;   Total days of mucositis after BMT

These studies may lead to new treatments and are adding insight into Ethyol etiology and treatment.

A major focus of Ethyol research is the development of new drugs and other treatment options. Studies seek to identify new drugs to treat various related disorders and to find safer, more effective doses for medications already being used. Other research is aimed at identifying receptors or drug targets.

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