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Famotidine Medical Research Studies

Up-to-date List of Famotidine Medical Research Studies

What Research is Being Done?

A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two main types of clinical studies: clinical trials (also called interventional studies) and observational studies. Following list includes both interventional and observational studies.

Latest Famotidine Medical Research Studies

Rank Status Study
1 Unknown  Esomeprazole or Famotidine in the Management of Aspirin Related Non-Ulcer Dyspepsia
Conditions: Aspirin;   Dyspepsia
Interventions: Drug: esomeprazole;   Drug: Famotidine
Outcome Measures: Treatment success : The HKDI is less than 16. Treatment was considered to have failed if a patient had taken medication for dyspepsia (other than antacids) during the study period;   Treatment success: no significant dyspepsia defined by the Global Dyspepsia Score
2 Recruiting Famotidine in Schizophrenia
Condition: Schizophrenia
Interventions: Drug: Famotidine;   Drug: Placebo
Outcome Measures: Change from Baseline in Positive and Negative Syndrome Scale (PANSS) at 8 weeks;   Change from Baseline in Clinical Global Impression (CGI) scale at 8 weeks;   Change from Baseline in Calgary Depression Scale (CDS) at 8 weeks;   Change from Baseline in The Overall Anxiety Severity and Impairment Scale (OASIS)at 8 weeks;   Change from Baseline in CogState scores at 8 weeks;   Change from baseline in nightly sleep duration measured with actigraphy at 8 weeks
3 Recruiting Open-label Safety and Pharmacokinetic Study of DUEXIS® (Ibuprofen and Famotidine) Tablets in Juvenile Idiopathic Arthritis
Condition: Juvenile Idiopathic Arthritis
Intervention: Drug: 800 mg ibuprofen/26.6 mg Famotidine
Outcome Measures: Safety of chronic treatment with DUEXIS in patients with JIA.;   Single dose PK study in a subset of patients with multiple dose PK sampling from all enrolled patients.;   Efficacy using American College of Rheumatology (ACR) Pediatric core set measures of JIA activity will be assessed at each study visit.;   Quality of Life (QOL)
4 Unknown  Platelet Inhibitory Effect of Clopidogrel in Patients Treated With Omeprazole, Pantoprazole, or Famotidine
Conditions: Coronary Heart Disease;   GI Bleeding
Intervention: Drug: PPI Platelet Inhibitory
Outcome Measure: Platelet function as assessed by a CPA system
5 Not yet recruiting Histamine Glutamate Antagonism in Stroke
Conditions: Acute Cerebrovascular Accident;   Cerebral Edema
Interventions: Drug: Diphenhydramine;   Drug: Pantoprazole;   Drug: Famotidine;   Drug: Dextromethorphan
Outcome Measures: Modified Rankin Score;   National Institutes of Health Stroke Severity (NIHSS) Scale;   Neurological examination of the subject;   All cause mortality data
6 Recruiting PPI vs H2RA in Patients With Helicobacter Pylori-Negative Idiopathic Bleeding Ulcers
Condition: Peptic Ulcer
Interventions: Drug: Lansoprazole;   Drug: Famotidine
Outcome Measures: Recurrent ulcer bleeding;   Recurrent ulcer detected by endoscopy at 24-month
7 Recruiting Study Of Three Different Stomach Acid Reducing Agents When Given With Palbociclib (PD-0332991) And Food
Condition: Healthy
Interventions: Drug: palbociclib commercial free base;   Drug: Famotidine;   Drug: rabeprazole;   Drug: antacid
Outcome Measures: Area Under the Curve From Time Zero to Extrapolated Infinite Time [AUC (0 - 8)];   Maximum Observed Plasma Concentration (Cmax);   Area Under the Curve From Time Zero to Last Quantifiable Concentration (AUClast);   Apparent Oral Clearance (CL/F);   Time to Reach Maximum Observed Plasma Concentration (Tmax);   Apparent Volume of Distribution (Vz/F);   Plasma Decay Half-Life (t1/2)
8 Recruiting Trial of Daily Pulse Interleukin-2 With Famotidine in Acute Myelogenous Leukemia
Condition: Acute Myelogenous Leukemia
Intervention: Drug: Interleukin-2
Outcome Measures: Event-free survival;   Patient response
9 Recruiting H2RA VS PPI for the Prevention of Ulcer Bleeding Associated With Low-dose Aspirin in Patients With Very High Ulcer Risk
Condition: Peptic Ulcer Bleeding
Interventions: Drug: Rabeprazole;   Drug: Famotidine
Outcome Measures: Recurrent ulcer bleeding;   Lower GI bleeding;   serious cardiothrombotic events
10 Recruiting Standard Infusion Carboplatin Versus Prophylactic Extended Infusion Carboplatin in Patients With Patients With Recurrent, Ovary, Fallopian Tube, and Primary Peritoneal Cancer
Conditions: Ovarian Cancer;   Fallopian Tube Cancer;   Peritoneal Cancer
Intervention: Drug: carboplatin
Outcome Measures: To determine if patients have lower rates of hypersensitivity reactions compared to those treated with standard infusion carboplatin.;   Determine the rate of successful planned treatment completion of carboplatin in each group;   Perform a cost-identification analysis of extended infusion carboplatin to estimate the cost per hypersensitivity reaction prevented.;   Perform exploratory analyses to correlate hypersensitivity rate to history of atopy, prior drug allergies, number of lifetime platinum cycles, duration since last platinum, and concomitant chemotherapy agent.
11 Recruiting Ruxolitinib W/ Preop Chemo For Triple Negative Inflammatory Brca
Conditions: Recurrent Breast Cancer;   Metastatic Breast Cancer
Interventions: Drug: Ruxolitinib;   Drug: Paclitaxel
Outcome Measure: Maximum Tolerated Dose of ruxolitinib

These studies may lead to new treatments and are adding insight into Famotidine etiology and treatment.

A major focus of Famotidine research is the development of new drugs and other treatment options. Studies seek to identify new drugs to treat various related disorders and to find safer, more effective doses for medications already being used. Other research is aimed at identifying receptors or drug targets.


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