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Ferro Medical Research Studies

Up-to-date List of Ferro Medical Research Studies

What Research is Being Done?

A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two main types of clinical studies: clinical trials (also called interventional studies) and observational studies. Following list includes both interventional and observational studies.

Latest Ferro Medical Research Studies

Rank Status Study
1 Recruiting A Study to Compare the Gastrointestinal Tolerability of Ferrochel®, Sumalate®,Ferrous Fumarate, Ferrous Sulfate, Ferric Glycinate, and Placebo
Condition: Anemia
Interventions: Dietary Supplement: Ferrochel® 90 mg;   Dietary Supplement: Sumalate® 90 mg;   Dietary Supplement: Ferrous fumarate 90 mg;   Dietary Supplement: Ferrous Sulfate 90 mg;   Dietary Supplement: Ferric Glycinate 90 mg;   Dietary Supplement: Placebo
Outcome Measures: Gastrointestinal questionnaire to measure the gastrointestinal tolerability;   the laboratory result to measure the change from baseline
2 Recruiting Comparison of NovaFerrum® vs Ferrous Sulfate Treatment in Young Children With Nutritional Iron Deficiency Anemia
Condition: Iron Deficiency Anemia
Interventions: Drug: elemental iron (NovaFerrum®);   Drug: elemental iron (Ferrous Sulfate)
Outcome Measures: Change in peripheral blood hemoglobin concentration;   Proportion of subjects with complete response to treatment
3 Recruiting Impact of Host Iron Status and Iron Supplement Use on Erythrocytic Stage of Plasmodium Falciparum
Conditions: Iron Deficiency Anemia;   Malaria
Intervention: Dietary Supplement: Iron Supplement
Outcome Measure:
4 Recruiting Malaria and the Safety of Iron Supplements and Iron Fortification
Condition: Iron Deficiency
Intervention: Dietary Supplement: Ferrous sulfate
Outcome Measures: Plasma non-transferrin-bound iron (NTBI);   Erythrocyte 58Fe incorporation;   Fractional 57Fe absorption
5 Unknown  A Trial of Iron Replacement in Patients With Iron Deficiency.
Conditions: Iron Deficiency;   Inflammatory Bowel Disease
Interventions: Drug: Iron Sucrose.;   Drug: Oral iron sulfate - active comparator
Outcome Measures: Improvement of iron saturation at week 8.;   To describe the change in the faecal bacteria composition pre and post iron replacement.;   To describe the changes in ferritin, haemoglobin, Hepcidin,IBDQ, Modified HBI and partial MAYO score in patients before and after iron replacement.;   To describe the changes in the colonic mucosal endoplasmic reticulum as an indicator of oxidative stress.;   To describe the changes in urinary metabolomics from iron replacement.;   Compare the health economics of intravenous versus oral iron replacement.
6 Not yet recruiting Fermented Iron-rich Supplement in Reducing Anemia
Condition: Iron Deficiency Anemia
Interventions: Dietary Supplement: supplement containing 60 mg iron sulfate;   Dietary Supplement: iron rich food supplement (60 mg iron);   Dietary Supplement: iron rich food supplement (10 mg iron);   Dietary Supplement: supplement containing 10 mg iron sulfate
Outcome Measures: iron deficiency anemia;   comparison of side effects of iron supplement
7 Recruiting Treatment of Iron Deficiency Anaemia in Inflammatory Bowel Disease With Ferrous Sulphate
Conditions: Ulcerative Colitis;   Crohn's Disease
Intervention: Drug: Ferrous sulphate
Outcome Measures: Mean increase in haemoglobin concentration.;   Tolerance of oral iron;   Change in disease activity (stool calprotectin);   Change in quality of life score;   Changes in mood;   Changes in fatigue;   Changes in stress levels
8 Recruiting IVICA: Intravenous Iron in Colorectal Cancer Associated Anaemia
Conditions: Anemia;   Colorectal Neoplasm
Interventions: Drug: Ferric carboxymaltose;   Drug: Ferrous Sulphate
Outcome Measures: To determine if the use of intravenous ferric carboxymaltose can reduce the need for allogeneic blood transfusion compare to oral ferrous sulphate in patients with colorectal adenocarcinoma related anaemia;   To determine differences in hemoglobin and hematinic markers between the groups.;   To determine differences in hepcidin levels in relation to blood profile changes in participants in the intravenous group.;   To determine differences in colonic mucosal expression of iron transport proteins, C-myc and NKD1 between the groups;   To determine differences in postoperative outcomes between the groups.;   To determine differences in anemia symptomatology response between groups.
9 Unknown  Erythropoietin and Early Iron Supplement and Retinopathy of Prematurity
Condition: Retinopathy of Prematurity
Intervention: Drug: erythropoietin and early iron supplements
Outcome Measure:
10 Recruiting The Safety and Effectiveness of Jobelyn in Pre-operative Management of Anaemia in Gynaecological Patients
Condition: Anemia
Interventions: Dietary Supplement: Jobelyn;   Drug: Ferrous Sulphate + Folic Acid
Outcome Measures: Anaemia;   morbidity
11 Recruiting Identification of Mechanism in the Erythroid Response in Patients With Myelodysplasia Undergoing Chelation Therapy
Conditions: Myelodysplasia;   Myelofibrosis;   Aplastic Anemia
Outcome Measure: To assess the molecular mechanism underlying the erythroid response
12 Unknown  Use of Iron Isomaltoside 1000 (Monofer) in Postpartum Anemia
Condition: Postpartum Anemia
Interventions: Drug: Iron isomaltoside 1000;   Drug: Ferrous sulphate
Outcome Measures: To see the rise in hemoglobin concentration of 2gm/dl or more.;   secondary - time required for rise in hemoglobin concentration
13 Recruiting Brain and Behavior Depending on Timing of Iron Deficiency in Human Infants
Conditions: Iron Deficiency;   Iron Deficiency Anemia
Interventions: Dietary Supplement: Ferrous Sulfate (liquid) + vitamins A and D;   Dietary Supplement: vitamins A and D;   Dietary Supplement: Ferrous sulfate (liquid)
Outcome Measures: Infant behavior and development;   Low or marginal birth iron;   Infant anemia
14 Unknown  Iron Absorption From Infant Formula and Iron Drops in Infants (MJAU-studien)
Conditions: Infant;   Dietary Supplements;   Food, Fortified
Interventions: Dietary Supplement: ferrous sulfate;   Other: iron-fortified infant formula (12.4 mg iron/L);   Other: iron-fortified infant formula (2.3 mg iron/L)
Outcome Measures: iron absorption;   indicators of iron metabolism, growth, and oxidative stress;   zinc absorption
15 Unknown  Iron Therapy in Colo-Rectal Neoplasm and Iron Deficiency Anemia: Intravenous Iron Sucrose Versus Oral Ferrous Sulphate.
Conditions: Colorectal Neoplasm;   Iron Deficiency Anemia
Interventions: Drug: i.v. iron sucrose;   Drug: Oral iron
Outcome Measures: Preoperative variations in hemoglobin.;   Postoperative variations in hemoglobin.;   Blood transfusion needs (pre, intra and postoperative);   Postoperative complications:;   - Pulmonary thromboembolism;   - Infections;   - Reintervention;   - Death;   Length of hospital stay
16 Unknown  Safety of Various Mode of Delivery of Iron Supplement on Iron Toxicity Markers in Preschool Children
Conditions: Iron Overload;   Oxidative Stress
Intervention: Dietary Supplement: Iron Supplementation
Outcome Measures: The effect of intervention on immune response, iron over load, oxidative stress markers and iron status;   Primary Outcome Measures: Mortality Incidence of disease requiring hospitalization interleukin response during severe illness or hospitalization
17 Recruiting Treatment Response of Injectafer vs. Oral Iron to Baseline Hepcidin Levels in Patients With Iron Deficiency Anemia (IDA) Secondary to Inflammatory Bowel Disease (IBD)
Condition: Iron Deficiency Anemia (IDA) Secondary to Inflammatory Bowel Disease (IBD)
Interventions: Drug: Injectafer;   Drug: Ferrous Sulfate tablets
Outcome Measure: Correlation between screening hepcidin and change in hemoglobin from baseline to highest observed hemoglobin change.
18 Recruiting Prevention of Iron Deficiency in Breastfed Infants
Conditions: Iron Deficiency;   Anemia
Interventions: Dietary Supplement: Fer-in-Sol;   Other: control
Outcome Measures: Iron deficiency anemia will be prevented in all infants before 5.5 mo of age;   Determine the number of infants with iron deficiency between 5.5 and 9 mo of age
19 Recruiting Iron Treatment for Young Children With Non-anemic Iron Deficiency
Condition: Non-anemic Iron Deficiency
Interventions: Dietary Supplement: Ferrous Sulfate;   Dietary Supplement: Placebo;   Behavioral: Dietary counseling
Outcome Measures: Mullen Scales of Early Learning;   Laboratory measures;   Child temperament
20 Unknown  Iron Supplementation of Lead-Exposed Infants
Condition: Lead Toxicity
Intervention: Drug: Ferrous sulfate
Outcome Measures: Incidence of blood lead concentrations > 10 mcg/dL;   Mean hemoglobin concentration;   Mean zinc protoporphyrin concentration;   Anthropometry;   Oxidative stress

These studies may lead to new treatments and are adding insight into Ferro etiology and treatment.

A major focus of Ferro research is the development of new drugs and other treatment options. Studies seek to identify new drugs to treat various related disorders and to find safer, more effective doses for medications already being used. Other research is aimed at identifying receptors or drug targets.

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