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Ferrous Medical Research Studies

Up-to-date List of Ferrous Medical Research Studies

What Research is Being Done?

A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two main types of clinical studies: clinical trials (also called interventional studies) and observational studies. Following list includes both interventional and observational studies.

Latest Ferrous Medical Research Studies

Rank Status Study
1 Recruiting A Study to Compare the Gastrointestinal Tolerability of Ferrochel®, Sumalate®,Ferrous Fumarate, Ferrous Sulfate, Ferric Glycinate, and Placebo
Condition: Anemia
Interventions: Dietary Supplement: Ferrochel® 90 mg;   Dietary Supplement: Sumalate® 90 mg;   Dietary Supplement: Ferrous fumarate 90 mg;   Dietary Supplement: Ferrous Sulfate 90 mg;   Dietary Supplement: Ferric Glycinate 90 mg;   Dietary Supplement: Placebo
Outcome Measures: Gastrointestinal questionnaire to measure the gastrointestinal tolerability;   the laboratory result to measure the change from baseline
2 Recruiting Comparison of NovaFerrum® vs Ferrous Sulfate Treatment in Young Children With Nutritional Iron Deficiency Anemia
Condition: Iron Deficiency Anemia
Interventions: Drug: elemental iron (NovaFerrum®);   Drug: elemental iron (Ferrous Sulfate)
Outcome Measures: Change in peripheral blood hemoglobin concentration;   Proportion of subjects with complete response to treatment
3 Recruiting Treatment of Iron Deficiency Anaemia in Inflammatory Bowel Disease With Ferrous Sulphate
Conditions: Ulcerative Colitis;   Crohn's Disease
Intervention: Drug: Ferrous sulphate
Outcome Measures: Mean increase in haemoglobin concentration.;   Tolerance of oral iron;   Change in disease activity (stool calprotectin);   Change in quality of life score;   Changes in mood;   Changes in fatigue;   Changes in stress levels
4 Not yet recruiting Safe and Efficacious Iron for Children in Kenya
Condition: Anaemia
Interventions: Dietary Supplement: Low-dose iron as NaFeEDTA;   Dietary Supplement: Conventional dose iron as Ferrous salt;   Dietary Supplement: Placebo
Outcome Measures: Hemoglobin concentration;   Iron status;   Serum concentration of non-transferrin bound iron;   Faecal calprotectin concentration;   P. falciparum infection;   Adherence to intervention
5 Recruiting Oral Iron vs. Placebo in Newly Diagnosed Gynecologic Oncology Patients Who Are Surgical Candidates.
Conditions: Ovarian Cancer;   Cervical Cancer;   Uterine Cancer;   Anemia
Interventions: Other: Oral Ferrous Fumarate;   Other: Placebo
Outcome Measures: Mean Difference in Hemoglobin;   Quality of life
6 Recruiting IVICA: Intravenous Iron in Colorectal Cancer Associated Anaemia
Conditions: Anemia;   Colorectal Neoplasm
Interventions: Drug: Ferric carboxymaltose;   Drug: Ferrous Sulphate
Outcome Measures: To determine if the use of intravenous ferric carboxymaltose can reduce the need for allogeneic blood transfusion compare to oral Ferrous sulphate in patients with colorectal adenocarcinoma related anaemia;   To determine differences in hemoglobin and hematinic markers between the groups.;   To determine differences in hepcidin levels in relation to blood profile changes in participants in the intravenous group.;   To determine differences in colonic mucosal expression of iron transport proteins, C-myc and NKD1 between the groups;   To determine differences in postoperative outcomes between the groups.;   To determine differences in anemia symptomatology response between groups.
7 Not yet recruiting The Use of Iron Therapy for Patients With Anemia After Surgery
Condition: Postoperative Anaemia
Interventions: Drug: Ferinject;   Drug: Ferrous fumarate;   Drug: Placebo for Ferrous fumarate;   Drug: Placebo for ferinject
Outcome Measures: Hemoglobin;   Quality of life;   Side effects of medication;   Predictive value of other parameters C reactive protein (CRP) ,transferrin, ferritin, hepcidin
8 Recruiting The Safety and Effectiveness of Jobelyn in Pre-operative Management of Anaemia in Gynaecological Patients
Condition: Anemia
Interventions: Dietary Supplement: Jobelyn;   Drug: Ferrous Sulphate + Folic Acid
Outcome Measures: Anaemia;   morbidity
9 Recruiting Iron Depletion and Replacement in Blood Donors
Condition: Anemia
Interventions: Dietary Supplement: Ferrous gluconate 325mg;   Behavioral: Nutrition counseling
Outcome Measures: Measure adherence to iron replacement therapy among blood donors;   Determine the feasibility of blood centers to implement an iron replacement therapy program.
10 Recruiting Malaria and the Safety of Iron Supplements and Iron Fortification
Condition: Iron Deficiency
Intervention: Dietary Supplement: Ferrous sulfate
Outcome Measures: Plasma non-transferrin-bound iron (NTBI);   Erythrocyte 58Fe incorporation;   Fractional 57Fe absorption
11 Unknown  Use of Iron Isomaltoside 1000 (Monofer) in Postpartum Anemia
Condition: Postpartum Anemia
Interventions: Drug: Iron isomaltoside 1000;   Drug: Ferrous sulphate
Outcome Measures: To see the rise in hemoglobin concentration of 2gm/dl or more.;   secondary - time required for rise in hemoglobin concentration
12 Unknown  Iron Therapy in Colo-Rectal Neoplasm and Iron Deficiency Anemia: Intravenous Iron Sucrose Versus Oral Ferrous Sulphate.
Conditions: Colorectal Neoplasm;   Iron Deficiency Anemia
Interventions: Drug: i.v. iron sucrose;   Drug: Oral iron
Outcome Measures: Preoperative variations in hemoglobin.;   Postoperative variations in hemoglobin.;   Blood transfusion needs (pre, intra and postoperative);   Postoperative complications:;   - Pulmonary thromboembolism;   - Infections;   - Reintervention;   - Death;   Length of hospital stay
13 Recruiting Treatment Response of Injectafer vs. Oral Iron to Baseline Hepcidin Levels in Patients With Iron Deficiency Anemia (IDA) Secondary to Inflammatory Bowel Disease (IBD)
Condition: Iron Deficiency Anemia (IDA) Secondary to Inflammatory Bowel Disease (IBD)
Interventions: Drug: Injectafer;   Drug: Ferrous Sulfate tablets
Outcome Measure: Correlation between screening hepcidin and change in hemoglobin from baseline to highest observed hemoglobin change.
14 Unknown  Treatment of Anemia in the 2nd Year of Life. Comparison of the Efficacy of Two Different Iron Preparations.
Conditions: Iron Deficiency;   Anemia
Intervention: Drug: Ferrous gluconate and iron polysaccharide complex
Outcome Measure: Hemoglobin
15 Not yet recruiting Treatment of Iron Deficiency Anemia With Pregnancy
Condition: Iron Deficiency Anemia of Pregnancy
Interventions: Drug: amino acid chelated iron;   Drug: iron salt (Ferrous fumarate)
Outcome Measures: change in hemoglobin level;   the occurence of side effects (abdominal colics, constipation, or metallic taste);   change in serum ferritin level
16 Unknown  Iron Supplementation of Lead-Exposed Infants
Condition: Lead Toxicity
Intervention: Drug: Ferrous sulfate
Outcome Measures: Incidence of blood lead concentrations > 10 mcg/dL;   Mean hemoglobin concentration;   Mean zinc protoporphyrin concentration;   Anthropometry;   Oxidative stress
17 Recruiting Iron Deficiency and Hereditary Haemorrhagic Telangiectasia
Condition: Hereditary Haemorrhagic Telangiectasia
Intervention: Drug: Ferrous sulphate 200mg oral tablet
Outcome Measure: Blood iron indices
18 Recruiting Brain and Behavior Depending on Timing of Iron Deficiency in Human Infants
Conditions: Iron Deficiency;   Iron Deficiency Anemia
Interventions: Dietary Supplement: Ferrous Sulfate (liquid) + vitamins A and D;   Dietary Supplement: vitamins A and D;   Dietary Supplement: Ferrous sulfate (liquid)
Outcome Measures: Infant behavior and development;   Low or marginal birth iron;   Infant anemia
19 Not yet recruiting A Pilot Study Comparing Tolerance of Oral Heme Iron Polypeptide With Oral Ionic Iron
Condition: Iron Deficiency
Interventions: Drug: ionic iron;   Drug: heme iron polypeptide
Outcome Measure: tolerance
20 Recruiting Capsule Endoscopy Versus Conservative Therapy for Obscure Gastrointestinal Bleeding
Conditions: Hemorrhage;   Anemia
Interventions: Drug: Ferrous sulfate;   Procedure: Capsule Endoscopy
Outcome Measures: Time to first blood transfusion after randomization;   Total number of blood transfusions;   Total number of hospitalizations;   Persistent Iron Deficiency Anemia as measured by ferritin and hemoglobin;   Total number of bleeding-related procedures performed after randomization;   Mortality

These studies may lead to new treatments and are adding insight into Ferrous etiology and treatment.

A major focus of Ferrous research is the development of new drugs and other treatment options. Studies seek to identify new drugs to treat various related disorders and to find safer, more effective doses for medications already being used. Other research is aimed at identifying receptors or drug targets.

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