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Fracture Medical Research Studies

Up-to-date List of Fracture Medical Research Studies

What Research is Being Done?

A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two main types of clinical studies: clinical trials (also called interventional studies) and observational studies. Following list includes both interventional and observational studies.

Latest Fracture Medical Research Studies

Rank Status Study
1 Recruiting Minimally Invasive Reduction and Fixation of Thoracolumbar Fractures
Conditions: Thoracic Fracture;   Lumbar Fracture
Intervention: Device: Fracture Fixation
Outcome Measures: Anterior wedge angle (AWA);   Blood loss of the patient during surgery to stabilize the spine Fracture;   OP duration;   Adverse events;   VAS Spine Score;   VAS pain score;   accompanying pain medication (or "self medication");   patient satisfaction with operational results;   Hospital length of stay
2 Unknown  Orbital Fractures Measurement: Intraoperative Versus Computed Tomography (CT) Scan
Condition: Orbital Fractures
Interventions: Procedure: operative Fracture size vs CT Fracture size;   Procedure: orbital Fracture intraoperative measurement
Outcome Measure: Patients with orbital Fractures that require surgical repair will have their Fracture"s" size measured intraoperatively by a ruler and/or a caliper in millimeters and compare it to the size measured by the CT scan.
3 Recruiting Radiostereometric Analysis of Fracture Healing in Distal Femur Fractures
Condition: Distal Femur Fractures
Intervention: Procedure: Placement of RSA beads
Outcome Measure: Change in inter-fragmentary motion throughout the course of healing for distal femoral Fractures.
4 Recruiting Partnership for Applied Research in Fracture Prevention Programs for the Elderly
Condition: Osteoporosis With Current Fragility Fracture
Intervention: Other: Integrated program
Outcome Measures: Incidence of secondary fragility Fracture;   Initiation of osteoporosis treatment by the primary care physician;   Compliance with osteoporosis treatment.;   Time to first fall event;   Incidence of secondary fragility Fractures.;   Number of clinically significant fall events.;   Fall-related hospitalizations;   Fragility Fracture-related death;   Participants' quality of life;   Practice of physical activities;   Fragility Fracture-related costs;   Admission to a long-term care facility;   Participants' perceptions of care integration;   Intervention participant's satisfaction with the fragility Fracture prevention program
5 Recruiting Management of Displaced Supracondylar Fractures of the Humerus Using Lateral vs. Crossed K-wires
Condition: Humeral Fractures
Interventions: Procedure: Crossed K-wiring of supracondylar Fracture of the humerus;   Procedure: Lateral K-wiring of supracondylar Fracture of the humerus
Outcome Measures: Loss of reduction between lateral K wires and crossed K wires in the treatment of supracondylar Fractures of the humerus (at pin removal);   Functional outcome (3 years post-op);   Rate of iatrogenic ulnar nerve injury
6 Recruiting Pathogenesis of Atypical Femur Fractures on Long Term Bisphosphonate Therapy
Conditions: Osteoporosis;   Atypical Femoral Fractures;   Prodromal Bone Deterioration
Interventions: Other: 500 without BP treatment;   Other: 500 with BP treatment
Outcome Measures: Prodromal bone deterioration (PBD);   Diagnosis of PBD
7 Unknown  Ultrasound Assisted Distal Radius Fracture Reduction
Conditions: Colles Fracture;   Point of Care Ultrasound;   Emergency Ultrasound
Intervention: Device: Point of care ultrasound
Outcome Measures: Efficacy of Point of care ultrasound in Identifying colles Fracture reduction;   Number of reduction attempts affected by ultrasound;   Time to imaging
8 Unknown  Early Rehabilitation After Hip Fracture
Conditions: Accidental Falls;   Fractures;   Hip Fractures
Interventions: Drug: cholecalciferol;   Behavioral: Physiotherapy
Outcome Measures: rate of falls compared between treatment arms;   rate of injurious falls;   number of persons who fell;   low-trauma Fractures (at the hip, forearm, humerus, pelvis, ankle, spine, femur, tibia);   disability;   quality of life (Euro-Qol);   mortality;   health care utilization;   admission to nursing home compared between treatment arms among subjects, who are community-dwelling prior to the index hip Fracture
9 Unknown  Pulsed Electromagnetic Field (PEMF) Stimulation for Tibia Fractures
Condition: Tibial Fractures
Intervention: Device: Pulsed electromagnetic field stimulation
Outcome Measures: Surgical revision rate in the 12 months after Fracture;   Fracture union rate at 12, 26 and 52 weeks after Fracture;   General health score and lower extremity functional score at 12, 26 and 52 weeks after Fracture
10 Unknown  Effect of PTH(1-34) Treatment on Fracture Healing in Vivo
Conditions: Shoulder Fractures;   Trochanteric Fractures
Intervention: Drug: rhPTH(1-34)
Outcome Measures: Radiological evaluation of healing;   Biochemical bone markers;   SF-36 questionnaire
11 Unknown  Bimodal Analgesia as Form of Pain Control Post Long Bone Fracture
Conditions: Tibia Fracture;   Femur Fracture;   Humerus Fracture
Interventions: Drug: Narcotics alone;   Drug: Narcotics and NSAIDS
Outcome Measures: pain score;   Amount of narcotics used;   time to Fracture healing;   return to activity;   complications;   reoperation rate
12 Recruiting Mortality Following Surgery for Proximal Femoral Fractures
Condition: Fracture of Neck of Femur (Hip)
Intervention: Procedure: hip Fracture surgery
Outcome Measures: in hospital mortality rate;   30 days mortality rate
13 Recruiting Pilon Fracture Reduction and Functional Outcome
Condition: Pilon Fracture of Tibia
Intervention:
Outcome Measures: Examine the influence of reduction quality on the primary functional outcome (as assessed using the Foot and Ankle Ability Measure (FAAM)) of patients with pilon Fractures treated with plate fixation.;   Patient outcome;   Frequency and severity of osteoarthritis (OA) following pilon Fractures;   Surgical details;   Pre- and postoperative treatment;   Frequency of local complications;   Effect of prognostic factors on the occurrence of complications;   To assess whether patient and surgeon expectations are met with regard to the trauma outcome
14 Unknown  Conservative or Operative Treatment of Fractures in the Neck of the 5th Metacarpal Bone
Condition: Fractures of the Neck
Intervention: Procedure: Bouquet pinning of the 5th metacarpal bone
Outcome Measures: Quick-DASH;   Patient satisfaction;   Pain;   Eq-5d;   Complications;   Sick-leave;   Range of motion in the joints in the 5th finger measured by hand therapist;   Grip strength;   Angular displacement in Fracture measured in lateral x-ray, and shortening in Fracture measured in AP view, of the 5th ray of the hand
15 Recruiting A Randomized Trial Comparing Conventional Plaster and Thermoplastic Splints to Treat Pediatric Boxer's Fractures
Conditions: Bone Fractures;   Splints;   Metacarpal Fracture;   Boxer's Fracture
Interventions: Other: Plaster Ulnar Gutter Splint;   Other: Thermoplastic Splint
Outcome Measures: Range of Motion;   Compliance;   Pain;   Complications;   Validated Outcome Questionnaire;   Grip Strength;   Radiographic assessment of Fracture
16 Not yet recruiting Teriparatide for Fracture Repair in Humans
Conditions: Osteoporosis, Age-Related;   Humeral Fractures
Interventions: Drug: Teriparatide;   Drug: Placebo
Outcome Measures: Identification of bone and callus patterns in the CT data at the Fracture site;   Finite Element Analysis (FEA) of QCT (quantitative computed tomography) data
17 Unknown  Comparison of Biodegradable & Metal Plates for Fixing Ankle Fracture
Conditions: Distal Fibular Fracture;   Bimalleolar Fracture;   Trimalleolar Fracture
Intervention: Device: biodegradable fixation system (Inion OTPS FreedomPlateTM)
Outcome Measure: The functional performance will be primarily determined by the Olerud and Molander Ankle Score
18 Recruiting Inflammatory Response Following Intraarticular Fracture
Condition: Intraarticular Fracture and Post-traumatic Osteoarthritis
Intervention:
Outcome Measure: Post-traumatic osteoarthritis (PTOA)
19 Unknown  Comparison Study of 3-4-screws-internal Fixation With Multi-screw-system Targon FN for Femoral Neck Fracture
Condition: Femoral Neck Fractures
Interventions: Device: screws-internal fixation;   Device: TARGON FN
Outcome Measures: overall survival, fixation survival and a composite end-point combining the two;   length of surgery, bleeding, ambulation
20 Recruiting Atypical Fracture Cohort Study
Conditions: Atypical Femur Fracture;   Atypical Subtrochanteric Fracture;   Osteoporosis With AFf
Intervention:
Outcome Measures: Prospectively identify and diagnose atypical Fracture patients in Ontario;   Examine risk factors and predictors for AFFs

These studies may lead to new treatments and are adding insight into Fracture etiology and treatment.

A major focus of Fracture research is the development of new drugs and other treatment options. Studies seek to identify new drugs to treat various related disorders and to find safer, more effective doses for medications already being used. Other research is aimed at identifying receptors or drug targets.


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