Up-to-date List of Gabapentin Medical Research Studies
What Research is Being Done?
A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two main types of clinical studies: clinical trials (also called interventional studies) and observational studies. Following list includes both interventional and observational studies.
Difference in pain control when adding Gabapentin to a multimodal pain management protocol in pediatric post-operative posterior spinal fusion patients.; Determine if opiate usage is less in the Gabapentin group versus control.
Symptom relief for chronic irritability in neurologically impaired children using Gabapentin.; Prevalence of associated gastrointestinal and sleep problems in neurologically impaired children and improvement using Gabapentin.
Persistent post surgical pain; Acute postoperative pain; Usage of epidural infusion of local and opioid analgesics (ml); Early postoperative pain; Consumption of opioid analgesics; Time to first request for additional analgesics; Analgesia related side-effects; Convalescence of gastrointestinal function; Health related quality of life; Patient satisfaction; Intensity of preoperative anxiety; Convalescence of lung function (spirometry); Sleep quality; Walking distance (meters); Fatigue; Hospital length of stay (days); Use of a vasopressor agent to correct hypotension
VAS score (VAS 0-100 mm) for maternal pain on movement at 24 hours after surgical incision.; VAS score on movement at 48 hours after surgical incision; VAS scores at rest at 24 and 48 hours after surgical incision; Maternal satisfaction scores at 24 and 48 hours after surgical incision.; Opioid use in the first 48 hours after surgical incision; Time to first analgesic; Sedation; Neonatal apgar scores; Breastfeeding issues; NICU admission
Hot Flashes in Men With Prostate Cancer Receiving Androgen Ablation Therapy
Drug: Gabapentin; Drug: Venlafaxine
Changes in quality of life; compare toxicity rates between the Gabapentin and venlafaxine treatment groups; Assess changes in the hot flash scores for the two arms; Assess changes in quality of life using the Hot flash related Daily Interference Scale (HFRDIS)
The primary outcome measure of this project are to test the prediction that pain from tampon insertion is lower in PVD patients when treated with Gabapentin compared to when treated with placebo.; The secondary outcome measure is to perform a mechanism-based analysis of Gabapentin effectiveness, and to gain insight into the underlying pathophysiology of subtypes of PVD that may lead to more specific treatment options.
The primary outcome will be the adequacy of symptom control during the last week of the study.; Secondary outcomes equate dyspepsia symptoms with quality of life. The Nepean Dyspepsia Index scores patients on five categories while the Global Overall Symptom Scale measures the severity of dyspepsia on a 1-7 scale.
improvement of symptom domain means decreased frequency to less than 8 micturitions per 24 hours, no urgency noted per 24 hrs and less that 3 wakening at bedtime for micturation.; Improvement of bladder function domain means increased bladder capacity and decreased overactive detrusor as recorded in urodynamic study.; Improvement in quality of life domain means increased overall quality of life as perceived and result in OAB-q
Rate of premature birth (before 37 weeks gestation)
These studies may lead to new treatments and are adding insight into Gabapentin etiology and treatment.
A major focus of Gabapentin research is the development of new drugs and other treatment options. Studies seek to identify new drugs to treat various related disorders and to find safer, more effective doses for medications already being used. Other research is aimed at identifying receptors or drug targets.