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Glipizide Medical Research Studies

Up-to-date List of Glipizide Medical Research Studies

What Research is Being Done?

A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two main types of clinical studies: clinical trials (also called interventional studies) and observational studies. Following list includes both interventional and observational studies.

Latest Glipizide Medical Research Studies

Rank Status Study
1 Recruiting Study to Understand the Genetics of the Acute Response to Metformin and Glipizide in Humans
Condition: Diabetes Mellitus, Type 2
Interventions: Drug: Glipizide;   Drug: Metformin;   Other: Oral Glucose Tolerance Test
Outcome Measures: Glipizide response;   Metformin response;   Incretin levels;   Proinsulin, glucagon;   Metabolomics;   Vitamin D
2 Recruiting A Study of MK-3102 in Participants With Type 2 Diabetes Mellitus With Chronic Kidney Disease or Kidney Failure on Dialysis (MK-3102-019)
Condition: Type 2 Diabetes Mellitus
Interventions: Drug: MK-3102;   Drug: Placebo to MK-3102;   Drug: Glipizide;   Drug: Placebo to Glipizide;   Biological: Insulin
Outcome Measures: Change from baseline in glycosylated hemoglobin (A1C);   Percentage of participants who experienced at least one adverse event;   Percentage of participants who discontinued from the study due to an adverse event;   Change from baseline in fasting plasma glucose (FPG);   Change from baseline in A1C;   Change from baseline in FPG;   Change from baseline in estimated glomerular filtration rate (eGFR);   Change from baseline in eGFR
3 Unknown  Outpatient Discharge Therapy With Saxagliptin+MetforminXR vs GlipizideXL for Type 2 Diabetes With Severe Hyperglycemia
Conditions: Diabetes Mellitus Type 2;   Severe Hyperglycemia - Blood Glucose Level >300mg/dl.
Interventions: Drug: Glipizide XL;   Drug: Saxagliptin + Metformin XR;   Drug: Metformin XR
Outcome Measures: The proportion of responders in each arm. Responder: FBG 70-300 and/or PPBG <400 mg/dl (week1-6), FBG 70-250 and/or PPBG <300 mg/dl (week 7-12) and without metabolic exclusion criteria, repeat ED visits, hospitalization or significant hypoglycemia.;   Proportion of patients achieving FBG goal of 70-130 mg/dl at 12 weeks in the 2 treatment arms;   Percentage of patients with symptomatic hypoglycemia;   To measure percentage compliance with medication in the two treatment arms.;   The number of fold increase in beta cell function in the 2 arms.
4 Recruiting Efficacy of Acarbose on Intestinal Microbiome and Incretins of Type 2 Diabetes
Condition: Type 2 Diabetes
Interventions: Drug: Glipizide;   Drug: Acarbose
Outcome Measure: euglycemia

These studies may lead to new treatments and are adding insight into Glipizide etiology and treatment.

A major focus of Glipizide research is the development of new drugs and other treatment options. Studies seek to identify new drugs to treat various related disorders and to find safer, more effective doses for medications already being used. Other research is aimed at identifying receptors or drug targets.

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