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Hip Medical Research Studies

Up-to-date List of Hip Medical Research Studies

What Research is Being Done?

A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two main types of clinical studies: clinical trials (also called interventional studies) and observational studies. Following list includes both interventional and observational studies.

Latest Hip Medical Research Studies

Rank Status Study
1 Recruiting HIP Fracture Accelerated Surgical TreaTment And Care tracK (HIP ATTACK) Trial
Condition: HIP Fractures
Intervention: Other: Accelerated medical clearance and surgery
Outcome Measures: Composite - major perioperative complication;   All-cause mortality;   Vascular mortality;   Non-vascular mortality;   Myocardial infarction;   Cardiac revascularization procedure;   Congestive heart failure;   New clinically important atrial fibrillation;   Nonfatal cardiac arrest;   Stroke;   Peripheral arterial thrombosis;   Pulmonary embolism;   Deep venous thrombosis;   Pneumonia;   Sepsis;   Infection;   Life-threatening bleeding;   Major bleeding;   New acute renal failure requiring dialysis;   Peri-prosthetic fracture;   Prosthetic HIP dislocation;   Implant failure;   HIP re-operation;   Time to first mobilization;   Length of hospital stay;   Length of critical care stay;   Length of rehabilitation stay;   New residence in a nursing home;   Functional Independence Measure (FIM™);   SF-36 score;   Delirium within 7 days of randomization;   Hospital readmission
2 Recruiting An Intelligent Instrument for Improved Leg Length and HIP Offset Accuracy in Total HIP Arthroplasty
Conditions: HIP Osteoarthritis;   Leg Length Discrepancy;   Dislocation
Interventions: Device: Intellijoint HIP;   Device: Outrigger
Outcome Measures: Accuracy of leg length;   Accuracy of HIP Offset;   Time of surgery;   Harris HIP Score;   Dislocation Rates;   Oxford HIP Scores
3 Not yet recruiting Health Improvement After Pregnancy (HIP) Program Randomized Control Trial
Condition: Metabolic Cardiovascular Syndrome
Intervention: Behavioral: HIP Program
Outcome Measures: Metabolic Syndrome Z Score;   Adherence to the HIP Program; Percent of Workouts Completed;   Differences in Biochemical Cardiovascular Risk Markers;   Change in Anthropomorphic Measurements and Blood Pressure from Baseline at Midpoint;   Change in Anthropomorphic Measurements and Blood Pressure from Baseline at Study Completion;   Change in Anthropomorphic Measurements and Blood Pressure from Midpoint to Study Completion;   Adherence to the HIP Program; Percent of Step Counting Completed;   Adherence to the HIP Program; Percent of Dietary Logs Completed
4 Recruiting The Metaphyseal HIP Prosthesis - Total HIP
Condition: Osteoarthritis of the HIP
Interventions: Device: Metaphyseal HIP Prosthesis;   Device: Stanmore HIP prosthesis
Outcome Measures: Radiostereometric Analysis (RSA);   Device related complications;   Harris HIP Score & HIP Osteoarthritis Outcome Score;   DEXA;   SF-12
5 Recruiting An Electronic Data Capture Study to Assess the Long-term Performance of the DePuy PROXIMA™ HIP in Primary Total HIP Replacement
Conditions: Rheumatoid Arthritis;   Osteoarthritis;   Post-traumatic Arthritis;   Avascular Necrosis;   Traumatic Femoral Fractures;   Congenital HIP Dysplasia
Intervention: Device: DePuy Proxima™ HIP
Outcome Measures: Kaplan-Meier survivorsHIP calculated at the five-year time-point;   Annual Kaplan-Meier survivorsHIP calculations;   Harris HIP Score;   Oxford HIP Score;   UCLA Activity Score;   HIP Outcome Score;   EuroQol EQ-5D;   Radiographic Analysis
6 Recruiting High Intensity Physiotherapy for HIP Fractures
Condition: HIP Fractures
Interventions: Other: Intensive physiotherapy;   Other: Usual Care
Outcome Measures: modified IOWA Level of Assistance Scale;   length of stay - acute and rehabilitation;   timed up and go;   Glasgow Outcomes Score -Extended;   discharge destination;   physical readiness for discharge;   12-Item Short Form Health Survey (SF-12);   EuroQOL five dimensions questionnaire (EQ-5D)
7 Recruiting Capsulectomy vs Capsulotomy With Repair in Direct Anterior Total HIP Arthroplasty
Conditions: HIP Arthrosis;   Osteoarthritis;   Arthritis
Interventions: Procedure: Capsulectomy in Direct Anterior Total HIP Arthroplasty;   Procedure: Capsulotomy in Direct Anterior Total HIP Arthroplasty
Outcome Measures: Range of Motion- Resisted HIP Flexion Strength;   Range of Motion - Maximum HIP Flexion;   Range of Motion - Maximum HIP Extension;   Range of Motion - Evidence of Flexion Contraction (Thomas Test);   Pain with Resisted HIP Flexion;   HIP Disability and Osteoarthritis Outcome Score;   Surgical Time;   Transfusion rate/%Hemoglobin Drop;   Stem seating height;   Adverse Events or Complications (acute dislocation rate, iatrogenic femur fracture, and delayed wound healing)
8 Unknown  Improving Quality of Care for HIP-Fracture Patients: Studies on Fast-track Surgery
Condition: HIP Fractures
Intervention:
Outcome Measure:
9 Recruiting Comparing Total HIP Arthroplasty and Hemi-Arthroplasty on Revision Surgery and Quality of Life in Adults With Displaced HIP Fractures (The HEALTH Study)
Conditions: HIP Fractures;   Femoral Neck Fractures
Interventions: Device: Total HIP arthroplasty;   Device: Hemi-arthroplasty
Outcome Measures: Revision surgery;   Function;   Complications, including mortality, dislocation, infection, femoral fracture, deep venous thrombosis, and prosthesis loosening;   Quality of life
10 Not yet recruiting Supine Sleeping After Total HIP Replacement
Conditions: Osteoarthritis;   HIP Dislocation
Interventions: Behavioral: Sleep position: no restrictions;   Behavioral: Sleep position: supine
Outcome Measures: Percentage early HIP dislocations;   HOOS;   VHS;   EQ-5D;   VAS/NRS HIP;   Compliance anti-dislocation instructions
11 Not yet recruiting Management of Hypotension In the Preterm Infant
Conditions: Hypotension;   Low Blood Pressure;   Intraventricular Hemorrhage of Prematurity
Interventions: Drug: Dopamine hydrochloride;   Drug: Dextrose 5%
Outcome Measures: First Co-Primary Outcome Measure: Survival to 36 weeks postmenstrual age free of severe brain injury;   Second Co-Primary Outcome Measure: Survival without moderate or serious disability as defined using consensus criteria for neurodevelopmental impairment.;   All cause mortality at 36 weeks gestational age
12 Recruiting The Health Influences of Puberty (HIP) Study
Conditions: Obesity;   Insulin Resistance;   Gonadal Dysfunction;   Type 2 Diabetes
Intervention: Drug: Metformin
Outcome Measures: Change in insulin sensitivity;   Change in insulin secretion;   Change in disposition index;   Change in lipid measures;   Change in insulin-like growth factor 1;   Change in testosterone;   Change in estradiol;   Change in sex hormone binding globulin;   Change in dehydroepiandrosterone sulfate;   Change in interleukin-6;   Change in high Sensitivity C-reactive protein;   Change in aspartate Aminotransferase (AST);   Change in alanine transaminase (ALT);   Change in urinary Luteinizing hormone;   Change in urinary Follicle-stimulating hormone;   Change in urinary estradiol metabolites;   Change in hemoglobin A1c;   Change in leptin;   Change in %body fat;   Change in visceral adipose;   Change in liver adipose
13 Recruiting Intramedullary Nail Versus Sliding HIP Screw Inter-Trochanteric Evaluation
Conditions: Femoral Neck Fractures;   Intertrochanteric Fracture
Interventions: Procedure: Gamma3 Intramedullary Nails (Stryker);   Procedure: Sliding HIP Screws
Outcome Measures: Health Related Quality of Life;   Fracture healing rates;   Fracture-related adverse events;   Revision surgery rates
14 Unknown  Evaluation of Locomotor Activity Before and After Total HIP Replacement in Patients With HIP Osteoarthritis.
Conditions: HIP Osteoarthritis;   Indication for Total HIP Replacement
Interventions: Other: Analysis of movement before total HIP replacement;   Other: Analysis of movement after total HIP replacement
Outcome Measure: Degree of patient statisfaction
15 Recruiting Comparing the Clinical Effects of Posterior Approach Versus Lateral Approach in Osteoarthritis Patients With a THA
Condition: Unilateral Primary Osteoarthritis of HIP
Intervention: Procedure: Total HIP arthroplasty
Outcome Measures: HIP Disability and Osteoarthritis Outcome Score (HOOS)-Physical Function Short form(HOOS-PS), 12 month;   HIP Disability and Osteoarthritis Outcome Score (HOOS)-pain, 12 month;   HIP Disability and Osteoarthritis Outcome Score (HOOS)-HIP related quality of life, 12 month;   University of California Los Angeles activity score (UCLA), 12 month;   EQ-5D self-rated health index -(using EQ VAS scores), 12 month;   The 20 meter walk-test (20MeWa);   "Timed Up and Go"- test (TUG), 3 month;   "Repeated chair rise"- test (RCR), 3 month;   30 seconds maximal repeated unilateral knee bending, 3 month;   Opioid consumption, 3 month;   Self-reported pain on a numerical ranking scale(NRS), 3 month;   HIP Disability and Osteoarthritis Outcome Score (HOOS)-pain, 3 month;   HIP Range of motion (ROM), 3 month;   Gait Deviation Index(GDI), 12 month;   Kinematic gait data, 12 month;   Temporospatial parameters, 12 month;   Electromyography (EMG) during walk, 12 month;   Isometric maximal voluntary muscle contraction(MVC), 12 month;   HIP Disability and Osteoarthritis Outcome Score (HOOS)-Activities of daily
16 Recruiting A Multi-centre Study to Assess the Long-term Performance of the Silent HIP™ in Primary Total HIP Replacement Surgery
Conditions: Primary Arthritis;   Secondary Arthritis
Intervention: Device: Silent™ HIP
Outcome Measures: Kaplan-Meier survivorsHIP;   Oxford HIP Score;   University of California Los Angeles (UCLA) Activity Score;   EuroQol EQ-5D;   Harris HIP Score;   Radiographic analysis
17 Unknown  InterTAN IM Nail Versus Sliding HIP Screw in Geriatric Fractures
Condition: HIP Fractures
Interventions: Device: sliding HIP screw;   Device: IntertAn IM nail
Outcome Measures: Functional Independence Measure (FIM);   Timed up an go (TUG);   2-minute walk test (2MWT);   Geriatric Depression Scale (GDS);   Lower Extremity Measure (LEM);   Complications;   Femoral shortening;   Blood Loss;   Mortality
18 Recruiting Analgesia After Total HIP Arthroplasty: Peri-Articular Injection Versus Epidural Patient Controlled Analgesia (PCA)
Condition: Osteoarthritis
Interventions: Procedure: Peri-Articular Injection;   Procedure: Epidural Patient Controlled Analgesia (Epidural PCA)
Outcome Measure: Time Until Patient is Ready for Discharge
19 Recruiting Multi-Site, Post-Market Study of the ICONACY I-HIP System
Condition: Degenerative Joint Disease
Intervention: Device: Iconacy HIP System
Outcome Measures: Radiographic Success as a Measure of Radiolucency and Component Migration;   Improvement of Harris HIP Score (with Charnley Score and other comorbidities considered);   Patient satisfaction clinical assessment utilizing questionnaire;   Revision of Implant Prosthesis as a Measure of Efficacy
20 Unknown  Efficacy of Preoperative Education and Mini-invasive Surgery for Total HIP Replacement
Condition: Osteoarthritis of the HIP
Intervention: Procedure: -preoperative education and total HIP replacement
Outcome Measures: Time to reach functional independence at hospital discharge;   Perioperative criteria :;   estimated blood loss;   duration of operation;   implant position;   implant fixation;   perioperative technical errors;   Postoperative during hospital stay:;   number of patients and number of units transfused before hospital discharge;   total estimated blood loss;   postoperative pain;   skin problems;   duration of hospital stay;   Postoperative (3, 6 and 12 months):;   Harris HIP score, SF-36, evaluation of satisfaction and expectation;   Abduction strength, balance and gate;   Scar assessment;   complications

These studies may lead to new treatments and are adding insight into Hip etiology and treatment.

A major focus of Hip research is the development of new drugs and other treatment options. Studies seek to identify new drugs to treat various related disorders and to find safer, more effective doses for medications already being used. Other research is aimed at identifying receptors or drug targets.


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