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Hydrocodone, Medical Research Studies

Up-to-date List of Hydrocodone, Medical Research Studies

What Research is Being Done?

A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two main types of clinical studies: clinical trials (also called interventional studies) and observational studies. Following list includes both interventional and observational studies.

Latest Hydrocodone, Medical Research Studies

Rank Status Study
1 Recruiting Prognostic Impact of Sleep Apnea on Cardiovascular Morbidity and Mortality, in End Stage Renal Disease Patients
Conditions: Obstructive Sleep Apnea;   End Stage Renal Disease
Interventions: Other: No Sleep Apnea;   Other: Sleep Apnea - untreated;   Device: Sleep Apnea - treated
Outcome Measures: Time to first major cardiovascular event;   Time to cardiovascular death;   Time to first non-fatal acute myocardial infarction;   Time to first hospitalization for acute myocardial ischemia;   Time to first acute heart failure;   Time to first non-fatal stroke;   Time to first acute peripheral vascular event
2 Not yet recruiting Testing the Elevation as Sleep Apnea Treatment
Conditions: Sleep Apnea, Obstructive;   Sleep Apnea Syndromes;   Sleep
Intervention: Behavioral: Head of bed elevation
Outcome Measure: Apnea-Hypopnea Index compared by the polysomnography standard versus polysomnography with the elevation of the head of the bed
3 Recruiting Echocardiographic Parameter and Sleep Apnea Changes After Mitral Valve Surgery
Condition: Sleep Apnea
Intervention: Procedure: Echocardiographic and sleep apnea test
Outcome Measures: Changes of left ventricular systolic function;   Changes of apnea-hypopnea index;   Changes of global longitudinal strain;   Changes of right ventricular systolic function
4 Recruiting Effect of Obstructive Sleep Apnea Syndrome on Insulin Sensitivity and Cardiovascular Risk in PCOS Adolescents
Conditions: Obstructive Sleep Apnea Syndrome;   Polycystic Ovary Syndrome;   Sleep Apnea
Intervention: Device: Nasal Continuous positive airway pressure (CPAP)
Outcome Measures: The purpose of this study is to understand how insulin function is affected and how endothelial function as a surrogate marker for cardiovascular risk is affected in presence of sleep apnea as compared to girls (13-21 yrs) with PCOS without sleep apnea;   We also want to see if there is any change in the levels of adipocytokines (Leptin, adiponectin, C Reactive Protein (CRP), Tumor Necrosis Factor (TNF) alpha, Free fatty acids) because of sleep apnea in obese PCOS adolescents.
5 Unknown  Pathophysiology of Central Apnoeas in Stroke Patients
Conditions: Central Apnoeas;   Stroke Patients
Intervention:
Outcome Measures: Baroreflexes;   Chemoreflexes;   Apnoea-hypopnoea index (AHI)
6 Unknown  Mechanisms of Endothelial Cell Dysfunction in Sleep Apnea
Conditions: Obstructive Sleep Apnea;   Intermittent Hypoxemia
Intervention: Device: Continuous Positive Airway Pressure (CPAP)
Outcome Measures: NTPDase (vascular enzyme) activity in white blood cells;   Circulating endothelial cells (CECs);   Determine the effect of sleep apnea therapy in increasing vascular enzyme (NTPDase) activity and decreasing the level of circulating endothelial cells (CECs).
7 Recruiting Sleep Apnea in Type 1 Diabetes
Condition: Type 1 Diabetes, Sleep Apnea Syndrome
Interventions: Other: Polysomnography;   Other: Evaluation of the autonomous nervous system;   Other: Clinical examination of the sleep;   Other: Clinical examination of diabetology;   Other: Biological dosages;   Other: Electrocardiogram (ECG);   Other: Carotid echography;   Other: Blood pressure
Outcome Measures: Compare the prevalence of sleep apnea syndrome by polysomnography between type 1 diabetic patients and healthy volunteers;   Precise if glycemic balance as defined by glycosylated hemoglobin<7% during the last three months is associated or not to sleep apnea syndrome;   Precise if the presence of an autonomic neuropathy (positive at 2 tests) is associated or not to sleep apnea syndrome;   Compare the patients with or without sleep apnea regarding consequences especially cardiovascular markers and coagulation factors;   Determine if the presence of sleep apnea syndrome has an impact upon quality of life and diabetes complications, micro or macroangiopathy;   Precise clinical symptoms in DT1 patients with Sleep apnea syndrome
8 Recruiting REV 002 Observational Study of the ReVENT Sleep Apnea System: Minimally Invasive Treatment for Obstructive Sleep Apnea
Condition: Obstructive Sleep Apnea
Intervention: Device: ReVENT Sleep Apnea System
Outcome Measures: Reduction in  Apnea-Hypopnea Index (AHI);   Patient perception of benefit as measured by change in daytime sleepiness and sleep-related quality of life
9 Not yet recruiting Effects of Treating Sleep Apnea in Patients With Congestive Heart Failure
Conditions: Obstructive Sleep Apnea;   Sleep Apnea;   Congestive Heart Failure;   Heart Failure
Interventions: Other: STOP-BANG Scoring Model;   Other: Polysomnogram Sleep Study
Outcome Measures: Number of Hospital Admissions;   Number of Hospitalized Days;   Number of Emergency Department Visits;   Epworth Sleepiness Scale;   Functional Outcome of Sleep Quality;   Residual Apnea Hypopnea Index;   % of nights with greater than 4 hours use of Continuous Positive Airway Pressure
10 Unknown  Obstructive Sleep Apnea and Genes Expression
Condition: Obstructive Sleep Apnea
Intervention: Procedure: Continuous Positive Airway Pressure (CPAP)
Outcome Measures: Apnea/Hypopnea Index;   Gene expression
11 Recruiting Sleep Apnea in Early to Mid-Stage Alzheimer's Disease
Conditions: Early Onset Alzheimer Disease;   Alzheimer Disease;   Obstructive Sleep Apnea Syndromes
Interventions: Device: CPAP Treatment;   Device: No treatment
Outcome Measures: Impact of the CPAP treatment on cognitive functions;   Rate of apnea/hypopnea events per hour (AHI/h);   Impact of CPAP treatment on neuropsychological evaluation parameters;   Impact of the CPAP treatment on Quality of Life
12 Unknown  Cardiovascular Phenotype Study in Patients With Obstructive Sleep Apnea Syndrome
Conditions: Obstructive Sleep Apnea Syndrome;   Hypertension
Interventions: Device: Positive airway pressure treatment;   Other: No positive airway pressure treatment
Outcome Measures: cardiovascular phenotype study in patients with non treated obstructive sleep apnea syndrome;   characterization of arterial blood pressure, sympathetic activity, functional and morphological cardiovascular modifications. Effect of a treatment of obstructive sleep apnea syndrome on those different parameters.
13 Recruiting Effect of Renal Transplantation on Obstructive Sleep Apnea in End Stage Renal Disease Patients (SASinTx)
Conditions: Obstructive Sleep Apnea;   Overhydration;   End Stage Renal Disease;   Renal Transplantation
Intervention: Procedure: Renal transplantation
Outcome Measures: Reduction of the obstructive sleep apnea severity;   Reduction in nocturnal leg fluid volume shift between the legs and the neck;   Relationship between overhydration, leg fluid volume shift, ankle and neck circumference and the severity of obstructive sleep apnea;   Change in the severity of the periodic limb movement disorder (PLMD);   Change in the severity of central sleep apnea
14 Recruiting SAS in Patients With Bronchial Carcinoma
Conditions: Sleep Apnea Syndrome;   Bronchial Carcinoma
Intervention: Device: sleep apnea screening with ApneaLinkTM
Outcome Measure: percent of sleep apnea in patients with bronchial carcinoma
15 Recruiting Obstructive Sleep Apnea in Bariatric Surgical Patients
Condition: Obstructive Sleep Apnea
Interventions: Other: Lab Sleep Study Group;   Device: Oximetry
Outcome Measures: The average cost for obstructive sleep apnea management;   The incidence of postoperative adverse events;   Number of visits to the health care professionals
16 Recruiting Multidisciplinary and Coordinated Follow-up Based on a Telemonitoring Web Platform for Improving CPAP Compliance in Low Cardiovascular Risk Sleep Apnea Patients : OPTISAS 1 Study
Conditions: Sleep Apnea Syndrome;   Low Cardiovascular Risk
Intervention: Device: Continuous Positive Airway Pressure (CPAP) in sleep apnea patients
Outcome Measures: Change from baseline CPAP compliance at 6 months;   Subjective Sleepiness;   Fatigue;   Quality of Life;   Health status;   Cost analysis
17 Recruiting Effects of Exercise Training on Cognitive Performance, Cerebral Metabolism and Sympathetic Activity in Obstructive Sleep Apnea
Condition: Obstructive Sleep Apnea
Intervention: Other: Exercise Training
Outcome Measure: effects of exercise training in patients with sleep apnea
18 Not yet recruiting Automate Detection of Sleep Apnea by ApneascanTM
Conditions: Sleep Apnea;   Arrhythmias
Interventions: Other: Apneascan TM;   Device: Polysomnography
Outcome Measures: Apnea-hypopnea index obtained from polysomnography and from autoscoring algorithms of the ApneaScan™ implantable impedance respiration sensor;   Malignant arrhythmogenic events detected daily by the ICD / CRT-D (AF, ES, supraventricular tachycardia, sustained and non sustained ventricular tachycardia, VF) and night by night AHI assessed by the ApneascanTM;   Weekly weight readings automatically and wirelessly sent to the LATITUDE(C);   Apnea and Hypopnea index measured 3 months after ICR or CRT-D implantation compared to the Apnea and Hypopnea index measured at baseline by the polysomnography
19 Unknown  A Community Pharmacist-led Intervention to Improve Screening of Sleep Apnea in Primary Care
Condition: Sleep Apnea
Intervention: Other: screening of sleep apnea
Outcome Measures: Proportion of patients referred by the general practitioner to sleep specialist for SAS diagnosis test;   Satisfaction of patients and pharmacists;   Proportion of patients with sleep apnea
20 Recruiting Sleep Schedules Modifications in Sleep Apnea Patients Treated by nCPAP
Condition: Obstructive Sleep Apnea
Intervention:
Outcome Measures: Total sleep time before and after CPAP therapy in obstructive sleep apnea patients;   Evolution of Physical activity (number of steps/day, mean daily time spent in activities > 3 METs, and mean daily energy expenditure; in Kcal)before and after CPAP therapy in OSA patients

These studies may lead to new treatments and are adding insight into Hydrocodone, etiology and treatment.

A major focus of Hydrocodone, research is the development of new drugs and other treatment options. Studies seek to identify new drugs to treat various related disorders and to find safer, more effective doses for medications already being used. Other research is aimed at identifying receptors or drug targets.


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