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Imaging Medical Research Studies

Up-to-date List of Imaging Medical Research Studies

What Research is Being Done?

A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two main types of clinical studies: clinical trials (also called interventional studies) and observational studies. Following list includes both interventional and observational studies.

Latest Imaging Medical Research Studies

Rank Status Study
1 Not yet recruiting Combined FDG-PET and 123I-Iodometomidate Imaging for Adrenal Neoplasia
Condition: Adrenal Gland Neoplasms
Interventions: Other: FDG positron emission tomography;   Other: Iodometomidate Imaging
Outcome Measures: Specificity of combined FDG-PET and 123I-IMTO Imaging for diagnosing adrenocortical adenoma;   Sensitivity of combined FDG-PET and 123I-IMTO Imaging for diagnosing adrenocortical adenoma
2 Recruiting IMAGE-HF Project I-A: Cardiac Imaging in Ischemic Heart Failure (AIMI-HF)
Conditions: Heart Failure;   Coronary Artery Disease;   Ischemic Cardiomyopathy;   Non-ischemic Cardiomyopathy
Interventions: Other: Advanced cardiac Imaging;   Other: Standard Cardiac Imaging
Outcome Measures: The time to occurrence of the first composite clinical endpoint.;   Change in LVEF as measured by echocardiography;   Change in NYHA symptom class based on telephone interview and/or clinical assessment;   QoL measures using validated questionnaires;   Resource utilization and cost;   All cause mortality.;   Change in NYHA symptom class based on telephone interview and/or clinical
3 Recruiting Whole Body Magnetic Resonance Imaging With Diffusion Weighted Imaging : Potential Role in Neurofibromatosis
Conditions: Whole Body Imaging;   Magnetic Resonance Imaging;   Neurofibromatosis 1;   Diffusion Magnetic Resonance Imaging;   Peripheral Nerve Sheath Tumors, Malignant
Intervention: Other: Additional Imaging or surgery
Outcome Measures: Estimation of total tumor load and diagnosis of high-risk neurofibromas;   To diagnose high-risk neurofibroma
4 Recruiting Database Registry to Examine Brain Connections and Brain Function in Mental Disorders
Conditions: Schizophrenia;   Schizoaffective Disorder
Outcome Measures: Differences in hippocampal subfield activation between people with schizophrenia (or schizoaffective disorder) and healthy volunteers;   Differences in glutamate neurotransmitters and glutamatergic function between people with schizophrenia (or schizoaffective disorder) and with healthy volunteers
5 Recruiting Simulated Screening Study for Breast Imaging
Conditions: Breast Cysts;   Breast Abnormalities;   Breast Tumors
Intervention: Procedure: Imaging modalities for breast cancer screening
Outcome Measures: Evaluation of new breast Imaging devices;   Determining the ratio of "patient call backs"
6 Recruiting 18F-FLT-PET Imaging of the Brain in Patients With Metastatic Breast Cancer to the Brain Treated With Whole Brain Radiation Therapy With or Without Sorafenib: Comparison With MR Imaging of the Brain
Condition: Metastatic Breast Cancer to the Brain
Intervention: Device: 18F-FLT-PET Imaging
Outcome Measures: radiographic response;   Analysis of surgical specimen
7 Unknown  Imaging of Traumatic Brain Injury
Condition: Traumatic Brain Injury
Outcome Measures: Identification of advanced MR Imaging markers;   level of cognitive function;   extent of disability;   level of orientation;   level of functional independence
8 Recruiting Magnetic Resonance Imaging of Gynecologic Malignancies Involving the Vagina
Condition: Vaginal Cancer
Interventions: Procedure: Magnetic Resonance Imaging (MRI);   Procedure: Diffusion Weighted Magnetic Resonance Imaging (DWMR)
Outcome Measures: Accuracy of Tumor Involvement Detection;   Ability of Diffusion Weighted Magnetic Resonance Imaging (DWMR) to Assess Response to Radiation Therapy
9 Not yet recruiting Post-Approval Clinical Study to Evaluate the Calcivis Caries Activity Imaging System
Condition: Dental Caries
Intervention: Device: Calcivis Caries Activity Imaging System
Outcome Measures: Measure of Performance of the Calcivis Caries Activity Imaging System;   Measure Safety of the Calcivis Caries Imaging System
10 Recruiting Imaging PAtients for Cancer Drug selecTion - Metastatic Breast Cancer
Condition: Metastatic Breast Cancer
Intervention: Procedure: Molecular Imaging
Outcome Measures: Clinical utility;   Correlation PET scans & progression-free survival (PFS);   Correlation of DNA and RNA analyses to Imaging, molecular analyses and follow-up data;   Correlation miRNA analysis to molecular analyses, Imaging & clincal follow-up data;   Correlation of peptide profiling to all other molecular, Imaging and clinical follow-up data;   Correlation of standard pathology results to all molecular, Imaging and clinical follow up data.;   Correlation of CTC analysis to all molecular, Imaging and clinical follow-up data;   Correlation circulating tumor DNA analysis to all other molecular, Imaging and clinical follow-up data;   Cost-effectiveness of molecular Imaging;   QoL
11 Not yet recruiting Nuclear Imaging Using 123I-mIBG (Adreview™ GE Healthcare) to Visually Identify Atrial Cardiac Innervation
Condition: Atrial Fibrillation
Intervention: Other: Nuclear Imaging
Outcome Measure: Concordance between nuclear images and catheter mapping of GP's pre and post ablation procedure.
12 Recruiting Optical Frequency Domain Imaging for Non-melanoma Skin Cancers
Condition: Non-Melanoma Skin Cancer (NMSC)
Intervention: Device: OFDI
Outcome Measure: Successful Imaging of lesion
13 Not yet recruiting Diffuse Optical Imaging With Indocyanine Green Solution in Imaging Pelvic Lymph Nodes in Patients With Stage II Prostate Cancer Undergoing Surgery
Conditions: Stage IIA Prostate Cancer;   Stage IIB Prostate Cancer
Interventions: Drug: indocyanine green solution;   Other: diffuse optical Imaging;   Procedure: robot-assisted laparoscopic surgery;   Procedure: therapeutic lymphadenectomy
Outcome Measures: Intraoperative detection of fluorescence in pelvic lymphatic tissue by near-infrared Imaging technology on the da Vinci Surgical System following direct injection of ICG into the prostate;   Quality of fluorescence as detected by near-infrared technology on the da Vinci Surgical System of lymphatic tissue at varying safe doses of ICG;   Lymph node yield;   Number of positive lymph nodes (nodes that contain cancer on final pathology)
14 Recruiting Narrow Band Imaging (NBI): A Novel Imaging Modality in Minimally Invasive
Conditions: Endometrial Cancer;   Fallopian Tube Cancer;   Ovarian Cancer;   Peritoneal Cancer;   Gastrointestinal Carcinoma;   Pancreatic Carcinoma;   Lung Cancer;   Esophageal Carcinoma
Intervention: Other: Narrow Band Imaging (NBI)
Outcome Measures: Determine the feasibility of Narrow Band Imaging (NBI) at the time of thorascopic, laparoscopic or robotic surgery.;   Determine what percentage of patients have surface metastasis identified with NBI that were not seen on white light Imaging.
15 Not yet recruiting Imaging During Surgery in Diagnosing Patients With Prostate, Bladder, or Kidney Cancer
Conditions: Bladder Cancer;   Kidney Tumor;   Prostate Cancer
Interventions: Procedure: photoacoustic Imaging;   Procedure: fluorescence Imaging;   Procedure: robot-assisted laparoscopic surgery
Outcome Measures: Margin/lesion status determined by histopathology (cancer status [positive vs negative] as well as grade [Gleason grade 1-5 for prostate cancer, high vs low grade for bladder cancer, and Fuhrman grade 1-4 for kidney cancer]);   Photoacoustic signal intensity (signal-to-noise ratio in the region of interest);   Hemoglobin content (lesion total hemoglobin) as determined by photoacoustic measurements;   Fluorescence intensity (signal-to-noise ratio in the region of interest);   Oxygen saturation (percent oxygen saturation in region of interest) as determined by photoacoustic measurements;   Subjective operator determined characteristics for ease of identification of pedicle, NV bundle, and lymph nodes (prostate cancer patients);   Subjective operator determined characteristics for ease of identification of pedicle, ureter, and lymph nodes (bladder cancer patients);   Subjective operator determined characteristics for ease of identification of hilum and tumor (kidney cancer patients)
16 Recruiting Testing and Calibration of Non-Invasive Optical Imaging Technology for Functional Brain Imaging
Conditions: Neurovascular Coupling;   Hemoglobin;   Functional Brain Imaging
Outcome Measure:
17 Recruiting Proflavine: A Feasibility Study for In Vivo Imaging of Oral Neoplasia
Condition: Head and Neck Cancer
Interventions: Drug: Proflavine;   Procedure: Imaging;   Device: Widefield Multispectral Imaging Devices;   Device: High-Resolution Microendoscope (HRME)
Outcome Measures: Feasibility Assessing Oral Mucosa In Vivo with Wide-field and High resolution Images using New Optical and Topically Contrast Agent;   Number of subjects and lesions successfully imaged with wide-field and high-resolution optical microscopes after topical application of contrast dye
18 Recruiting Optical Imaging of Skin Cancers for Margin Delineation of Non-melanoma Skin Cancers
Condition: Skin Cancer
Intervention: Procedure: Optical Imaging
Outcome Measure: Evaluate use of fluorescence and reflectance Imaging, and confocal microscopy for non-invasive detection of skin tumor margins in head and neck region
19 Unknown  Stress Adenosine Cardiac Magnetic Resonance (MR) Comparison With Single Photon Emission Computed Tomography (SPECT) Imaging
Conditions: Coronary Artery Disease;   Cardiac Perfusion
Interventions: Procedure: SPECT Imaging;   Procedure: Stress Adenosine CMR
Outcome Measure: Stress adenosine cardiac MRIis not inferior to SPECT Imaging in diagnosing myocardial ischemia
20 Recruiting Improved Breast Sweep Imaging With Fourier Transform
Condition: Breast Cancer
Intervention: Device: Magnetic resonance Imaging
Outcome Measures: Optimize Sweep Imaging with Fourier Transform magnetic resonance Imaging (SWIFT MRI) for Breast;   Assess Accuracy Relative to Biopsy

These studies may lead to new treatments and are adding insight into Imaging etiology and treatment.

A major focus of Imaging research is the development of new drugs and other treatment options. Studies seek to identify new drugs to treat various related disorders and to find safer, more effective doses for medications already being used. Other research is aimed at identifying receptors or drug targets.

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