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Injury Medical Research Studies

Up-to-date List of Injury Medical Research Studies

What Research is Being Done?

A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two main types of clinical studies: clinical trials (also called interventional studies) and observational studies. Following list includes both interventional and observational studies.

Latest Injury Medical Research Studies

Rank Status Study
1 Recruiting Cincinnati Home Injury Prevention Study
Condition: Injury in the Home
Intervention: Other: Injury Intervention Group
Outcome Measures: Any modifiable and medically-attended Injury in enrolled children;   Correlation of self-reports of non-emergent but medically attended residential injuries in enrolled children.
2 Recruiting Healthy Homes Healthy Children (H3C)
Condition: Injury in the Home
Intervention: Other: Injury Prevention Measures
Outcome Measures: Any modifiable and medically-attended Injury in enrolled children sustained in the home;   Presenteeism / Absenteeism at work due to child's Injury
3 Recruiting Canadian Eye Injury Registry
Condition: Eye Injuries
Intervention: Behavioral: Public Health strategies
Outcome Measures: Number and type of eye injuries occurring in Canada;   Ocular Trauma Score
4 Recruiting Helping Children's Centres to Enhance Home Safety
Conditions: Burns;   Smoke Inhalation Injury
Interventions: Behavioral: Injury Prevention Briefing Plus facilitation;   Behavioral: Injury Prevention Briefing
Outcome Measures: The proportion of families who have a fire escape plan (ascertained from self-completion questionnaire).;   The proportion of Childrens Centres providing information and advice on the prevention of fire-related Injury including
5 Recruiting Traumatic Brain Injury - Knowledge Translation
Condition: Traumatic Brain Injury
Intervention: Other: Computerized clinical decision support
Outcome Measure: Change in proportion of cranial CT use in children with minor blunt head trauma at very low risk of clinically important traumatic brain injuries
6 Not yet recruiting Treatment of Splenic Trauma: a Retrospective Cohort Study
Condition: Splenic Injury
Intervention: Procedure: Treatment of splenic Injury
Outcome Measures: type of splenic trauma treatment;   Mortality;   Length of hospital stay;   Length of stay in the intensive care unit;   Emergency procedures
7 Recruiting Mission Connect Mild Traumatic Brain Injury (TBI) Integrated Clinical Protocol
Conditions: Mild Traumatic Brain Injury;   Post-traumatic Stress Disorder
Interventions: Drug: Atorvastatin;   Drug: Placebo
Outcome Measures: Subjects with mild traumatic brain Injury (MTBI) treated with atorvastatin for 7 days after MTBI will show a significant improvement in outcome, as measured by the Rivermead Post-Concussion Symptoms Questionnaire, administered at 3 months after Injury.;   MTBI subjects treated with atorvastatin for 7 days after mild TBI will show fewer symptoms of PCS and PTSD at 3 months post Injury than those receiving placebo.;   MTBI subjects treated with atorvastatin for 7 days after mild TBI will show greater cognitive recovery and higher functional outcome than those receiving placebo.;   MTBI subjects treated with atorvastatin for 7 days after mild TBI will show better preservation of whole brain volumes and reduced white matter abnormalities at 3 months post-Injury than placebo treated subjects.;   There will be no significant difference in liver function tests between the subjects treated with atorvastatin for 7 days and those receiving placebo.;   There will be no significant difference in clinical findings of liver dysfunction (jaundice, discolored urine, fatigue, or unexplained fever) or in other reported symptoms between subjects treated with atorvastatin for 7 days and those receiving placebo.
8 Recruiting Laparoscopy Versus Clinical Follow up to Detect Diaphragm Injury
Condition: Diaphragm Injury
Interventions: Procedure: Laparoscopy;   Other: Clinical follow up
Outcome Measure: To assess the clinical outcome of potential occult diaphragm injuries in patients presenting at the Groote Schuur trauma centre with left sided thoracoabdominal stab wounds, if an expectant non operative management course is taken.
9 Not yet recruiting Influence of Cognitive Rest on Minor Traumatic Brain Injury
Condition: Minor Head Injury
Interventions: Other: Cognitive rest;   Other: Usual care
Outcome Measures: Minor traumatic brain Injury symptoms;   Days of work or school missed;   Visits to the emergency department or other health care professionals
10 Unknown  Effect of Passive Gait Training on the Cortical Activity in Patients With Severe Brain Injury.
Conditions: Craniocerebral Trauma;   Traumatic Brain Injury;   Subarachnoid Hemorrhage;   Anoxic Brain Injury
Intervention: Behavioral: Tilt Table With Integrated Stepping System
Outcome Measures: EEG:frequency ratios: Alpha versus delta; alpha and beta versus delta and theta; ERP: latency of P300-component.;   EEG: absolute and relative power in every frequency band; median frequency;
11 Recruiting TBI Project Amsterdam
Condition: Traumatic Brain Injury
Outcome Measures: The white-matter integrity of children with TBI will be compared to children with traumatic control injuries;   Performance on tests of attention will be compared between children with TBI and children with traumatic control injuries;   Parental reports of behavioural regulation will be compared between children with TBI and children with traumatic control injuries;   Academic achievement will be compared between children with TBI and children with traumatic control injuries;   Performance on test of reinforced learning will be compared between children with TBI and children with traumatic control injuries
12 Recruiting Treatment of Acute, Unstable Chest Wall Injuries
Conditions: Blunt Injury of Thorax;   Flail Chest;   Chest Wall Injury Trauma;   Rib Fracture
Intervention: Procedure: Surgical fixation
Outcome Measures: Ventilator-free days (VFD);   Number of days in the Intensive Care Unit (ICU);   Amount of pain medication administration, converted to oral morphine equivalence;   Rate of Pneumonia;   Pulmonary function assessment;   Rate of return to work;   assessment of functional health and well being
13 Not yet recruiting Hormone Deficiency After Brain Injury During Combat
Conditions: Traumatic Brain Injury;   Hypopituitarism
Intervention: Other: Blast Traumatic Brain Injury
Outcome Measures: Prevalence of anterior pituitary dysfunction;   Prevalence of posterior pituitary dysfunction
14 Unknown  Dissemination of Injury Interventions
Conditions: Fall Injury;   Elderly
Interventions: Other: facilitative system;   Other: Standard Program
Outcome Measure: Emergency department and in-patient hospitalization for fall Injury
15 Recruiting North American Clinical Trials Network (NACTN) for Treatment of Spinal Cord Injury
Condition: Spinal Cord Injury
Outcome Measure: American Spinal Injury Association Impairment Scale
16 Recruiting Timing and Intensity of the Exposures and Attributable Burden of Acute Lung Injury
Conditions: Acute Lung Injury;   Acute Respiratory Distress Syndrome
Outcome Measures: Development of ALI;   Quality adjusted survival
17 Recruiting Study of Sand Versus Wood Chip Surfaces on School Playgrounds to Minimize Injury in School Children
Conditions: Wounds and Injuries;   Closed Head Injury
Intervention: Behavioral: school playgrounds
Outcome Measures: Upper extremity fracture rates;   Fracture rates, upper extremity;   Head Injury rates;   All Injury rates
18 Recruiting Hormonal Deficiency in the Quality of Life of Patients With Traumatic Brain Injury
Condition: Traumatic Brain Injury (TBI)
Intervention: Other: MRI scan and endocrinology analysis
Outcome Measures: Evolution of the SF-36(Short-Form health survey)score up to 18 months post-trauma;   QOLIBRI (Quality of Life after Brain Injury) measure #1;   Questions on Life Satisfaction-Hypopituitarism (QLS-H) measure #2;   Tests of Attentional, mnesic and executive performances #3;   Functional outcomes (#4):The Glasgow Outcome Scale (GOS)-Score;   Functional outcome #5 :the Functional Independence Measure (FIM)
19 Recruiting The EPIC Project: Impact of Implementing the EMS Traumatic Brain Injury Treatment Guidelines
Conditions: Brain Injuries, Traumatic;   Injuries, Acute Brain;   TBI (Traumatic Brain Injury)
Intervention: Other: The National Prehospital TBI Management Guidelines
Outcome Measures: Survival;   hospital length of stay;   Intensive care unit length of stay;   ventilator days;   Patient disposition
20 Recruiting Vestibular Rehabilitation and Balance Training After Traumatic Brain Injury
Conditions: Traumatic Brain Injury;   Brain Concussion;   Head Injury;   Dizziness
Interventions: Other: Multidisciplinary evaluation and VR;   Other: Multidisciplinary evaluation
Outcome Measures: Dizziness Handicap Inventory (DHI);   High level mobility assessment tool for traumatic brain Injury (HiMAT)

These studies may lead to new treatments and are adding insight into Injury etiology and treatment.

A major focus of Injury research is the development of new drugs and other treatment options. Studies seek to identify new drugs to treat various related disorders and to find safer, more effective doses for medications already being used. Other research is aimed at identifying receptors or drug targets.

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