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Kombiglyze Medical Research Studies

Up-to-date List of Kombiglyze Medical Research Studies

What Research is Being Done?

A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two main types of clinical studies: clinical trials (also called interventional studies) and observational studies. Following list includes both interventional and observational studies.

Latest Kombiglyze Medical Research Studies

Rank Status Study
1 Recruiting Korean Post-marketing Surveillance for Kombiglyze XR®
Condition: Diabetes Mellitus, Type 2
Intervention:
Outcome Measures: Occurrence of known and unexpected adverse events, especially serious adverse events;   Incidence of adverse events under the routine drug use;   Effectiveness of Kombiglyze XR as assessed by change from baseline in Hemoglobin A1c (HbA1c), Fasting plasma glucose (FPG), and 2-hour post-prandial glucose (2-hr PPG);   Safety information related to factors (eg, gender, demographics etc) that may affect the safety of the drug based on incidence rates of AEs;   Safety information related to factors (eg, gender, demographics etc) that may affect the effectiveness of the drug based on incidence rates of AEs;   Safety information related to overdose, drug-to-drug interaction and laboratory abnormalities based on incidence rates of AEs
2 Recruiting Saxagliptin + Metformin Compared to Saxagliptin or Metformin Monotherapy in PCOS Women With Impaired Glucose Homeostasis
Conditions: Polycystic Ovary Syndrome;   Disorder of Glucose Regulation
Interventions: Drug: Metformin XR;   Drug: Saxagliptin;   Drug: Saxagliptin-Metformin XR
Outcome Measures: Fasting and 2 hour glucose levels after glucose load;   ß-cell compensatory function;   Surrogate measures of insulin sensitivity and secretion;   Cardiometabolic risk factors;   Free androgen index

These studies may lead to new treatments and are adding insight into Kombiglyze etiology and treatment.

A major focus of Kombiglyze research is the development of new drugs and other treatment options. Studies seek to identify new drugs to treat various related disorders and to find safer, more effective doses for medications already being used. Other research is aimed at identifying receptors or drug targets.


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