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Levate Medical Research Studies

Up-to-date List of Levate Medical Research Studies

What Research is Being Done?

A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two main types of clinical studies: clinical trials (also called interventional studies) and observational studies. Following list includes both interventional and observational studies.

Latest Levate Medical Research Studies

Rank Status Study
1 Not yet recruiting High-Sensitivity Troponin in the Evaluation of Patients With Acute Coronary Syndrome
Conditions: Acute Coronary Syndrome;   Myocardial Infarction
Intervention: Device: High-sensitivity troponin I assay
Outcome Measures: Recurrent myocardial infarction or cardiovascular death at 1 year;   Duration of stay;   Recurrent myocardial infarction;   Unplanned coronary revascularization;   Cardiovascular death;   All cause death;   Heart failure hospitalization;   Major hemorrhage;   Minor hemorrhage;   Recurrent unplanned hospitalization excluding acute coronary syndrome;   Non-cardiovascular death
2 Unknown  High-dose Chemotherapy With Autologous Stem Cell Rescue in Pediatric High-risk Brain Tumors
Condition: Brain Tumor
Intervention: Procedure: high-dose chemotherapy and autologous stem cell rescue
Outcome Measures: overall survival, event-free survival;   toxicity
3 Recruiting "Effect of High Fat and High Glycemic Diets
Condition: Type 2 Diabetes
Interventions: Behavioral: High Glycemic Diet;   Behavioral: Control diet
Outcome Measures: Insulin Sensitivity;   ceramides and diacylglycerol
4 Recruiting Comparison of High-dose IL-2 and High-dose IL-2 With Radiation Therapy in Patients With Metastatic Melanoma.
Condition: Metastatic Melanoma
Interventions: Other: Radiation therapy and high-dose IL-2;   Drug: High-dose IL-2
Outcome Measures: Change in diameter of target lesions;   Response rate in crossover patients
5 Recruiting Effect of High-protein High-fiber Diet in Patients With Autoimmune Hepatitis
Conditions: Autoimmune Hepatitis;   Cirrhosis
Intervention: Dietary Supplement: High protein high fiber diet
Outcome Measures: Nutritional Status;   Minimal hepatic encephalopathy;   Quality of life
6 Recruiting Solute Removal With High Volume Hemodiafiltration Versus Long High Flux Hemodialysis
Condition: End-stage Renal Disease
Interventions: Device: High volume post dilution hemodiafiltration;   Device: high flux hemodialysis
Outcome Measure: Uremic retention solute concentrations from pre and post dialysis blood samples,dialyzer inlet and outlet blood samples,and spent dialysate samples.
7 Recruiting Study Comparing High-Dose Flu Vaccine to Standard Vaccine in Cancer Patients Less Than 65 Receiving Chemotherapy
Conditions: Cancer;   Influenza Viral Infections
Interventions: Biological: Standard Trivalent Influenza Vaccine;   Biological: High-Dose Influenza Vaccine
Outcome Measures: The Geometric Mean Titer (GMT) of high-dose influenza vaccine vs the standard trivalent influenza vaccine in adult subjects on chemotherapy who are less than 65 years old.;   The seroprotection rate of high-dose influenza vaccine vs standard trivalent influenza vaccine in adult subjects on chemotherapy less than 65 years old.;   The seroconversion rate of high-dose influenza vaccine versus standard trivalent influenza vaccine in adult subjects on chemotherapy less than 65 years old.;   Evaluate and compare the local and systemic adverse events to both vaccines.
8 Unknown  Tandem High-dose Chemotherapy and Autologous Stem Cell Rescue in Patients With High-risk Neuroblastoma
Condition: Neuroblastoma
Intervention: Procedure: tandem high-dose chemotherapy
Outcome Measure: Overall survival and event-free survival, short-term and long-term toxicity of tandem high-dose chemotherapy and autologous stem cell transplantation
9 Not yet recruiting High Intensity Training in Patients With Spinal and Bulbar Muscular Atrophy
Conditions: Spinal and Bulbar Muscular Atrophy;   Healthy Subjects
Interventions: Other: Supervised high intensity training;   Other: Optional training;   Other: Control period;   Other: Unsupervised High intensity training
Outcome Measures: Incremental test;   Functional test;   Self-rated muscle fatigue, muscle pain and activity level;   Serum concentrations of Creatine Kinase (CK);   Activity level
10 Recruiting High Fructose Corn Syrup
Conditions: Nonalcoholic Fatty Liver Disease;   Obesity
Interventions: Behavioral: High fructose corn syrup diet;   Behavioral: Standard diet (low in high fructose corn syrup)
Outcome Measures: Change in intrahepatic triglyceride(IHTG)content;   Hepatic lipid metabolism;   Multi-organ insulin sensitivity;   Uric acid metabolism
11 Recruiting Physiological Study of Low-frequency HFO/HFO-TGI and High-frequency HFO
Conditions: Acute Respiratory Distress Syndrome;   Acute Cor Pulmonale
Intervention: Other: High Frequency Oscillation
Outcome Measures: Right ventricular diastolic area, left ventricular diastolic area as determined by transesophageal echocardiography during the application of the tested ventilatory strategies.;   Eccentricity index as determined by transesophageal echocardiography during the application of the tested ventilatory strategies;   PaO2, PaCO2 and arterial pH during the application of the tested ventilatory strategies;   Mean arterial pressure during the application of the tested ventilatory strategies;   Cardiac index during the application of the tested ventilatory strategies;   Static Compliance of the Respiratory System before and after the application of the tested HFO strategies
12 Recruiting Pathway M-1: Sphenopalatine Ganglion Stimulation for the Treatment of Chronic or High Frequency, High Disability Migraine Headache
Conditions: Chronic Migraine;   High Frequency, High Disability Migraine
Intervention: Device: ATI Neurostimulation System
Outcome Measures: Major Device- and Surgical-Related Complications;   Effective Therapy;   Headache Frequency;   Pain Relief at 1 Hour;   Pain Freedom at 1 Hour;   Migraine Associated Symptom Relief at 1 Hour;   Disability and Quality of Life;   Global Evaluation of SPG Stimulation Therapy;   Prophylactic Medication Use;   Acute Medication Use
13 Unknown  Transient Lower Esophageal Sphincter Relaxations and High Resolution Manometry
Condition: Healthy Volunteers
Intervention: Device: Esophageal high resolution manometry associated or not with manometry with perfused Dentsleeve probe (as determined by randomization)
Outcome Measures: The primary outcome is to demonstrate that high resolution manometry allows the detection of meal-induced tLESr. All recordings will be analyzed at the end of each examination and reviewed at the end of the enrolment.;   To compare the number of tLESr detected by high resolution manometry and those detected by manometry with perfused dentsleeve probe.;   To define the characteristics (duration, relaxation amplitude) of high resolution manometry-detected tLESr.
14 Recruiting High Intensity Interval Training in Chronic Stroke Patients
Condition: Stroke
Interventions: Other: High intensity aerobic training;   Other: High Intensity Strength Training;   Other: Mixed Training
Outcome Measures: 6 minutes walking test (6-MWT);   10 meters Walking test (10-MtWT);   Time Up and Go Test (TUG);   Gait analysis;   Strength;   Arterial - venous oxygen difference (a-v O2 diff);   Cardiac Output (CO);   Oxygen Uptake Efficiency Slope (OUES);   Activities- specific Balance Confidence Scale:;   SF-36 Health Survey Questionnaire;   Stroke Impact scale;   Peak of Oxygen Consumption (VO2peak);   Walking energy cost (Wc)
15 Not yet recruiting Utility of High-Fidelity Simulation In the Education and Assessment of Residents in the Recognition and Management of the Sepsis Syndrome
Conditions: Medical Knowledge;   Clinical Performance
Intervention: Other: Debriefing of high-fidelity sepsis simulation scenarios
Outcome Measures: Performance on a written assessment of the recognition and management of early sepsis in the hospitalized patient.;   Performance on a practical assessment of the recognition and management of early sepsis in the hospitalized patient.;   Self-assessment of knowledge and ability in the recognition and management of early sepsis in the hospitalized patient.
16 Recruiting High Flow Nasal OXygen Therapy in High Risk Patients of Hypoxia Undergoing Diagnostic BRONCHOscopy
Condition: Hypoxia
Intervention: Device: HFNOT
Outcome Measures: Success rate of bronchoscopy;   frequency and duration of hypoxia;   switch to oxygen therapy method;   change of respiratory symptoms
17 Recruiting High-protein High-fiber Diet in Patients With Primary Biliary Cirrhosis
Condition: Primary Biliary Cirrhosis
Intervention: Dietary Supplement: High protein high fiber diet
Outcome Measures: Nutritional status;   Minimal hepatic encephalopathy;   Quality of life
18 Unknown  Effect of High Fiber and Sugar Free Biscuits in Prediabetics Population
Condition: Impaired Glucose Tolerance
Intervention: Dietary Supplement: High fiber sugar free biscuit
Outcome Measures: HbA1c;   Insulin, Fasting Glucose,Ketone Body, Fructosamine.
19 Unknown  Tandem Peripheral Blood Stem Cell (PBSC) Rescue for High Risk Solid Tumors
Conditions: Ewing's Sarcoma;   Soft Tissue Sarcoma;   Hepatoblastoma;   Hodgkin's Disease;   Germ Cell Tumor
Intervention: Drug: High-Dose Chemotherapy with Tandem PBSC Rescue.
Outcome Measures: Determine the feasibility and toxicity of tandem PBSC rescue following high dose chemotherapy as consolidation in pediatric patients with high risk solid tumors.;   Evaluate length of remission and long term disease free survival in chemotherapy responsive high-risk pediatric solid tumor patients treated using this approach.;   Evaluate correlation between cell dose and time to engraftment in high-risk pediatric solid tumor patients treated using this approach.
20 Unknown  High-Field MRI Characterization of Wrist and Hand Cartilage Abnormalities in Inflammatory and Chronic Rheumatisms
Conditions: Abnormality;   Inflammation;   Rheumatism
Intervention: Other: high-field MRI (3 Teslas)
Outcome Measures: can be obtained, one could expect an early detection of joint abnormalities;   will be to develop a quantitative analyse of the corresponding high-resolution images.

These studies may lead to new treatments and are adding insight into Levate etiology and treatment.

A major focus of Levate research is the development of new drugs and other treatment options. Studies seek to identify new drugs to treat various related disorders and to find safer, more effective doses for medications already being used. Other research is aimed at identifying receptors or drug targets.

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