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Loratadine Medical Research Studies

Up-to-date List of Loratadine Medical Research Studies

What Research is Being Done?

A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two main types of clinical studies: clinical trials (also called interventional studies) and observational studies. Following list includes both interventional and observational studies.

Latest Loratadine Medical Research Studies

Rank Status Study
1 Recruiting Evaluation of Loratadine for Prevention of Pegfilgrastim-Induced Pain
Condition: Pegfilgrastim-induced Back and Leg Pain
Interventions: Drug: Loratadine;   Drug: placebo
Outcome Measures: Prevention of pegfilgrastim-induced back and leg pain by administration of the antihistamine Loratadine;   Identification of adverse events when Loratadine is given to prevent pegfilgrastim-induced back and leg pain;   Incidence of pegfilgrastim-induced back and leg pain
2 Recruiting NOLAN: Naproxen or Loratadine and Neulasta
Condition: Bone Pain in Stage I - III Breast Cancer
Interventions: Drug: Naproxen;   Drug: Loratadine
Outcome Measures: Bone pain (all grade) in cycle 1;   Bone pain (all grade) by cycle (2-4) and across cycles;   Severe (grade 3/4) bone pain by cycle and across cycles;   Subject reported bone pain;   Maximum Subject Reported bone pain;   Area under the Curve for subject-reported bone pain;   Adverse Event and Serious Adverse Events;   Severity of Adverse Events
3 Recruiting Long-Term Efficacy and Safety Study of SCH 900237/MK-8237 in Children and Adults With House Dust Mite-Induced Allergic Rhinitis/Rhinoconjunctivitis (P05607)
Conditions: Rhinitis, Allergic, Perennial;   Rhinitis, Allergic, Nonseasonal
Interventions: Biological: MK-8237 tablets;   Biological: Placebo tablets;   Drug: Rescue Medication: Self-Injectable Epinephrine;   Drug: Rescue Medication: Loratadine tablets;   Drug: Rescue Medication: Olopatadine ophthalmic drops;   Drug: Rescue Medication: Mometasone furoate nasal spray
Outcome Measures: Average Total Combined Rhinitis Score (TCRS);   Number of Participants Who Experience At Least One Adverse Event;   Number of Participants Who Discontinue Study Drug Due to an Adverse Event;   Average Rhinitis Daily Symptom Score (Rhinitis DSS);   Average Total Combined Rhinoconjunctivitis Score (TCS);   Average Rhinitis Daily Medication Score (Rhinitis DMS);   Average Allergic Rhinitis/Rhinoconjunctivitis Symptoms Assessed by Visual Analogue Scale (VAS)
4 Unknown  Combination of Peripheral Nerve Block and DepoDur in Total Knee Joint Replacement
Condition: Arthroplasty, Replacement, Knee
Interventions: Drug: Depodur;   Procedure: sciatic nerve block
Outcome Measures: Postoperative Pain;   Time Required for Placement of Block;   Time to first use of rescue analgesia and PCA;   Total opioid consumption;   Degree of knee flexion (Range of motion);   Day of first ambulation;   Number of days required to achieve a 110° knee flexion;   Number of days of hospitalization;   Need for manipulation of knee joint under general anesthesia;   Secondary effects: nausea and vomiting, pruritus, supplemental oxygen, urinary catheterization;   Satisfaction score

These studies may lead to new treatments and are adding insight into Loratadine etiology and treatment.

A major focus of Loratadine research is the development of new drugs and other treatment options. Studies seek to identify new drugs to treat various related disorders and to find safer, more effective doses for medications already being used. Other research is aimed at identifying receptors or drug targets.


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