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Lotensin Medical Research Studies

Up-to-date List of Lotensin Medical Research Studies

What Research is Being Done?

A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two main types of clinical studies: clinical trials (also called interventional studies) and observational studies. Following list includes both interventional and observational studies.

Latest Lotensin Medical Research Studies

Rank Status Study
1 Recruiting Renal Protective Effects of Renin Angiotensin System (RAS) Inhibitor in Peritoneal Dialysis Patients
Condition: Renal Function Disorder
Interventions: Drug: Benazepril;   Drug: Valsartan;   Drug: Benazepril+Valsartan;   Drug: Control
Outcome Measures: The longitudinal change in residual glomerular filtration rate (GFR);   Dialysis adequacy;   Peritoneal membrane function;   Blood pressure;   The time to anuria;   Death
2 Recruiting Safety of Dual Blockage of Rennin-angiotensin System in Patients With Advanced Renal Insufficiency
Condition: Renal Insufficiency, Chronic
Interventions: Drug: Benazepril;   Drug: Losartan;   Drug: Benazepril+Losartan
Outcome Measures: The proportion of patients with increase in serum potassium ≥6.0 mmol/L.;   The proportion of patients with serum creatinine increase >30%;   The proportion of patients with drug-related cough;   The proportion of patients with hopotension (systolic blood pressure <110 mmHg despite withdrawal of all additional antihypertensive medication);   The proportion of patients with non-fatal cardiovascular events
3 Recruiting Post-preeclampsia Renal Project: Study of Nephroprotection in Women Having Suffered Preeclampsia
Condition: Renal Alteration
Interventions: Drug: Placebo;   Drug: Benazepril hydrochloride
Outcome Measures: microalbuminuria excretion rate (spot or 24h);   eGFR;   Filtration fraction %;   24h Ambulatory Blood Pressure;   Effective Renal Plasma Flow;   Adverse Events
4 Not yet recruiting Chronic Angiotensin Converting Enzyme Inhibitors in Intermediate Risk Surgery
Condition: Hypertension
Interventions: Drug: Take ACE-I;   Drug: Hold ACE-I
Outcome Measures: Intraoperative Hypotension;   Acute Renal Failure;   Low blood pressure subgroup;   Older age subgroup;   Postoperative Hypertension
5 Recruiting Is There an Adverse Drug Reaction Between Renin-Angiotensin System Blockade and Inhaled Anesthetics
Condition: Hypertension
Intervention: Other: Sevoflurane/oxygen/air/nitrous oxide
Outcome Measures: Systemic Vascular Resistance Index (SVRI);   Heart Rate;   Systolic Blood Pressure;   Diastolic Blood Pressure;   Central Venous Pressure;   Cardiac Output (CO);   Cardiac Index (CI);   Stroke Volume Varriation;   Systemic Vascular Resistance

These studies may lead to new treatments and are adding insight into Lotensin etiology and treatment.

A major focus of Lotensin research is the development of new drugs and other treatment options. Studies seek to identify new drugs to treat various related disorders and to find safer, more effective doses for medications already being used. Other research is aimed at identifying receptors or drug targets.

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