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Lower Medical Research Studies

Up-to-date List of Lower Medical Research Studies

What Research is Being Done?

A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two main types of clinical studies: clinical trials (also called interventional studies) and observational studies. Following list includes both interventional and observational studies.

Latest Lower Medical Research Studies

Rank Status Study
1 Recruiting Randomized Trial of Exercise on Lower Extremity Edema After Lymphadenectomy in Gynecologic Cancer
Condition: Gynecologic Cancer
Intervention: Other: Pelvic and Lower extremity exercise
Outcome Measures: Change in Lower extremity edema-related symptoms after pelvic and Lower extremities exercise;   the compliance rate of management guidelines for Lower extremity edema, the performance rate for pelvic and Lower extremity exercise
2 Recruiting Correlations of 3D Urethral and Paraurethral Sonographic Findings With Urodynamic Studies, Lower Urinary Tract Symptoms & Sexual Dysfunction in Female Patients With Lower Urinary Tract Symptoms.
Conditions: Lower Urinary Tract Dysfunction;   Overactive Bladder Syndrome
Intervention:
Outcome Measures: Urethral/pelvic blood flow perfusion pattern between subgroups of women with Lower urinary tracts;   Urethral/pelvic blood flow perfusion pattern after antimuscarinics
3 Unknown  The Effect of an Opioid on the Lower Esophageal Sphincter During Anesthesia Induction
Condition: Lower Esophageal Sphincter
Interventions: Drug: alfentanil;   Drug: saline
Outcome Measure: Changes in barrierpressure (in mmHg) in the area of the Lower esophageal sphincter.
4 Recruiting Human-Machine System for the H2 Lower Limb Exoskeleton
Conditions: Stroke;   Hemiparesis
Interventions: Behavioral: Robot-assisted training with the H2 Lower limb powered exoskeleton;   Behavioral: Supervised motor practice
Outcome Measures: Change from baseline in Fugl-Meyer Assessment - Lower Extremity Motor Function;   Change from baseline in Functional Gait Assessment;   Change from baseline in Lower limb joint kinematics during walking;   Change in cortical dynamics measured by Electroencephalography (EEG);   Change in robotic measure of performance measured by the H2;   Change from baseline in Berg Balance Scale score;   Change from baseline in distance walked during the 6-minute walk test;   Change from baseline in Timed Up and Go Test score
5 Not yet recruiting The Effectiveness of a Bladder Training Video for Management of Lower Urinary Tract Symptoms.
Conditions: Nonneurogenic Lower Urinary Tract Dysfunction;   Dysfunctional Elimination Syndrome
Intervention: Other: Educational Intervention
Outcome Measures: Improvement of Nonneurogenic Lower Urinary Tract Dysfunction symptoms;   Assess the Quality of Life of children with Nonneurogenic Lower Urinary Tract Dysfunction/Dysfunctional Elimination Syndrome.
6 Recruiting The Effect of Lower Limb Deformities (LLD) on Children's Gait and on Energy Expenditure
Conditions: Lower Limbs Deformities;   Gait;   Energy Expenditure
Intervention:
Outcome Measure: Lower limbs deformities defined as (a) Lower limb mechanical axis deviation of 1.5 centimeters or more(b) Deviation of 5 degree or more from the normal values in the joint orientation angles
7 Recruiting Study of Electroencephalogram (EEG) Measurement During Different Stimulations of the Lower Urinary Tract
Conditions: Healthy;   Nonneurogenic Neurogenic Bladder Dysfunction;   Neurogenic Bladder Dysfunction Nos
Intervention: Other: Electroencephalography
Outcome Measure: Establishment of somatosensory evoked potentials of Lower urinary tract stimulations
8 Unknown  E-STIM Trial: Comparing the Efficacy of the Empi Select TENS to a Control for the Treatment of Chronic Lower Back Pain
Condition: Lower Back Pain
Interventions: Device: Empi Select TENS Device;   Device: Placebo
Outcome Measures: Relief of Lower back pain as measured by a Numerical Rating Scale (NRS) of Average Daily Pain.;   Improvement of function as measured by the Roland and Morris Back Pain Disability Scale.;   Improvement of quality of life as measured by the SF-12 Health Survey.;   Subject satisfaction as measured by the Patient Global Impression of Change scale (PGIC).;   Adverse Event Assessment: assess the occurrence and severity of any adverse events.
9 Recruiting Comparison of Saphenous Vein Graft Harvested From Upper Versus Lower Leg in Coronary Artery Bypass Grafting
Conditions: Triple Vessel Disease;   Unstable Angina;   Stable Angina;   Myocardial Infarction
Interventions: Procedure: Upper leg vein harvesting;   Procedure: Lower leg vein harvesting
Outcome Measure: Endothelial preservation of saphenous vein graft
10 Recruiting Lower-Limb Drainage Mapping in Pelvic Lymphadenectomy for Gynaecological Cancer
Condition: Gynaecological Malignant Tumours With Indication of Pelvic Lymphadenectomy
Intervention: Procedure: Lower-limb drainage isotopic intraoperative detection
Outcome Measures: Lower-limb drainage intraoperative isotopic detection rate in patients with pelvic lymphadenectomy for gynaecological cancers.;   Anatomy of Lower-limb drainage;   Percentage of patients with metastatic Lower limb sampling;   Follow-up of patients to identify complications, and namely Lower-limb lymphedema.
11 Recruiting The Effect of Lowered Physical Activity on Insulin Sensitivity and Lipid and Glucose Metabolism
Condition: Immobilization
Intervention: Other: unilateral Lower limb suspension
Outcome Measures: Insulin sensitivity;   intramyocellularlipid content;   Lipid intermediates;   Lipid metabolism;   Glucose metabolism
12 Unknown  Strategy for Adequate Blood Pressure Lowering in the Patients With Intracranial Atherosclerosis
Condition: Brain Ischemia
Interventions: Procedure: Aggressive BP Lowering;   Procedure: modest blood pressure Lowering
Outcome Measures: Ischemic lesion volume change in the whole forebrain on fluid attenuation inversion recovery (FLAIR) magnetic resonance imaging (MRI);   Ischemic lesion volume change in the territory of symptomatic intracranial disease on FLAIR MRI;   The number of patients with new ischemic lesion in the whole forebrain on FLAIR MRI;   The number of cardiovascular event;   The number of vascular death;   The number of adverse event;   The number of adverse drug reaction;   The number of adverse drug reaction related to experimental drug
13 Recruiting Lower Urinary Tract Dysfunction Database
Conditions: Neurogenic Bladder;   Diseases of the Lower Urinary Tract: General Conditions
Intervention:
Outcome Measure: Survival of the patients
14 Recruiting Study on the Reapplication of Chloraprep After Lower Extremity Surgery and Prior to Dressing Application
Conditions: Lower Extremity Surgery;   Surgical Site Infection;   Bacterial Colonization;   Surgical Antiseptic
Intervention: Drug: Chloraprep
Outcome Measures: quantitative bacterial colonization;   positive culture rate;   bacterial strain identification
15 Recruiting Efficacy of Foot Orthotics in Veterans With Chronic Lower Back Pain
Condition: Back Pain Lower Back Chronic
Interventions: Device: Custom Foot Orthotic;   Device: Sham Orthotic
Outcome Measures: Visual Analog Scale (VAS);   Modified Oswestry Disability Index (mODI);   Patient Reported Outcome Measurement Information System (PROMIS) Physical Function
16 Recruiting External Compression Therapy for Secondary Prevention of Lower-Limb Loss and Cardiovascular Mortality
Condition: Amputation of Lower Limb
Intervention: Device: ArtAssist© Device
Outcome Measure: Amputation free survival
17 Recruiting Efficacy of Osteopathic Manipulative Medicine (OMM) and Phototherapy for Patients With Chronic Lower Back Pain
Condition: Chronic Lower Back Pain
Interventions: Procedure: Osteopathic Manipulative Medicine;   Procedure: Phototherapy
Outcome Measures: 10 cm visual analog scale for quantitative back pain;   SF-36 Health Survey to measure Quality of Life;   The Oswestry Back Questionnaire to measure qualitative back pain
18 Recruiting Supraspinal Control of Lower Urinary Tract Function in Healthy Controls & Patients With Bladder Dysfunction
Conditions: Neurogenic Lower Urinary Tract Dysfunction;   Multiple Sclerosis;   Overactive Bladder;   Spinal Cord Injury
Interventions: Other: fMRI;   Other: bladder filling;   Other: bladder cooling;   Other: additional post-treatment fMRI scan
Outcome Measures: Bold signal;   Structural and functional connectivity;   Side effects
19 Not yet recruiting The Effect of Enhanced External Counterpulsation Treatment to Lower Urinary Tract Symptoms
Condition: Lower Urinary Tract Symptoms
Intervention: Device: Enhanced external counterpulsation(EECP)
Outcome Measures: evaluated Lower urinary tract symptoms by International Prostate Symptom Score;   Urinary flow rate
20 Recruiting Ultrasound Measure of the Thickness of the Lower Segment in Women Having a History of Caesarian
Conditions: Lower Uterine Segment;   Labor
Intervention: Other: Ultrasound
Outcome Measures: Maternal morbidity;   Foetal mortality;   New born morbidity;   rate of iterative elective caesarians

These studies may lead to new treatments and are adding insight into Lower etiology and treatment.

A major focus of Lower research is the development of new drugs and other treatment options. Studies seek to identify new drugs to treat various related disorders and to find safer, more effective doses for medications already being used. Other research is aimed at identifying receptors or drug targets.


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