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Lunesta Medical Research Studies

Up-to-date List of Lunesta Medical Research Studies

What Research is Being Done?

A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two main types of clinical studies: clinical trials (also called interventional studies) and observational studies. Following list includes both interventional and observational studies.

Latest Lunesta Medical Research Studies

Rank Status Study
1 Recruiting Eszopiclone for the Treatment of Posttraumatic Stress Disorder
Condition: Posttraumatic Stress Disorders
Interventions: Drug: Eszopiclone;   Drug: Placebo
Outcome Measures: Symptoms of Posttraumatic Stress Disorder;   Sleep disturbance;   Memory recall bias;   Inflammatory markers (cytokines)
2 Recruiting Effects of Eszopiclone on Sleep and Memory in Schizophrenia
Condition: Schizophrenia
Interventions: Drug: eszopiclone;   Drug: placebo
Outcome Measures: sleep spindles;   Motor procedural memory performance
3 Unknown  Eszopiclone and Inflammatory Mediators in Patients With Acute Coronary Syndrome
Conditions: Acute Coronary Syndrome;   Sleep Disorder
Interventions: Drug: Eszopiclone;   Other: Placebo
Outcome Measures: Changes in circulating inflammatory cytokines (Interleukin [IL]-1B, IL-6, IL-10, and Tumor Necrosis Alpha [TNF-α]) and pro-coagulant mediators (soluble P-selectin and CD40 ligand).;   Changes in objective and subjective measures of sleep
4 Recruiting Sleep Effectiveness and Insulin and Glucose Homeostasis
Conditions: Diabetes;   Prediabetic;   Prediabetes;   Glucose Intolerance
Intervention: Drug: eszopiclone
Outcome Measures: change in continuous glucose profile;   change in Sleep effectiveness biomarkers
5 Unknown  A Non-inferiority Study With Two Treatment Arms Eszopiclone 3 mg Versus Zopiclone 7.5 mg - for the Treatment of Insomnia
Condition: Insomnia
Interventions: Drug: Eszopiclone;   Drug: Zopiclone
Outcome Measures: Latency to persistent sleep measured by polysomnography;   Efficiency using the variables latency time to persistent sleep, frequency of night awakenings, time awake during bedtime, early morning awakening, total time in bed, total time awake and sleep efficiency
6 Unknown  How do Sleeping Pills Affect Pain in the Brain?
Condition: Primary Insomnia
Intervention: Drug: Eszopiclone
Outcome Measure: Sleep and pain ratings following 1 week of treatment as compared to baseline
7 Not yet recruiting Auricular Acupuncture for Primary Insomnia
Condition: Primary Insomnia
Interventions: Other: auricular acupuncture(AA);   Other: sham AA;   Drug: Eszopiclone;   Drug: placebo
Outcome Measures: Sleep Onset Latency(SOL);   Pittsburgh Sleep Quality Index(PSQI);   Insomnia Severity Index (ISI);   Beck Depression Inventory (BDI);   State-Trait Anxiety Inventory (STAI);   Self-rating Anxiety Scale (SAS);   The Epworth Sleeping Scale (ESS);   Flinders Fatigue Scale (FFS);   The MOS 36-Item Short-Form Health Survey questionnaire (SF-36);   Total Sleep Time (TST);   Sleep Efficiency (SE);   Wake After Sleep Onset (WASO)
8 Recruiting Combination Therapy to Treat Sleep Apnea
Condition: Sleep Apnea, Obstructive
Interventions: Drug: Placebo pill;   Drug: Sedative;   Other: Room air;   Other: Oxygen
Outcome Measures: Model prediction of absence/presence of OSA;   Apnea-Hypopnea Index

These studies may lead to new treatments and are adding insight into Lunesta etiology and treatment.

A major focus of Lunesta research is the development of new drugs and other treatment options. Studies seek to identify new drugs to treat various related disorders and to find safer, more effective doses for medications already being used. Other research is aimed at identifying receptors or drug targets.

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