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Luveris Medical Research Studies

Up-to-date List of Luveris Medical Research Studies

What Research is Being Done?

A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two main types of clinical studies: clinical trials (also called interventional studies) and observational studies. Following list includes both interventional and observational studies.

Latest Luveris Medical Research Studies

Rank Status Study
1 Recruiting Comparison of Assisted Reproductive Technology (ART) Outcomes Between Two Protocols of Induction of Ovulation in Patients With Hypogonadotropic Hypogonadism
Condition: Infertility
Interventions: Drug: Lutropin alfa;   Drug: Follitropin alfa and Lutropin alfa
Outcome Measures: number of follicles;   Size of follicle;   Endometrial thickness;   number of oocytes retrieved;   Fertilization rate;   Biochemical pregnancy rate;   Clinical pregnancy rate;   Implantation rate
2 Unknown  To Describe the Effect of rhLH Supplementation in Women With Hyporesponse to rhFSH After Pituitary Downregulation
Condition: Infertility
Intervention: Drug: Luveris
Outcome Measures: Number of oocyte retrieved;   1. Oestrodial on hCG day (pg/ml) Safety: adverse events;   2. Number of embryos;   3. Implantation rate (%);   4. Clinical pregnancy rate (%);   5. Ongoing PR per IVF cycle (%);   6. Abortion rate (%);   7. Ampoules of rFSH;   8. FertiQoL score Safety: adverse events
3 Recruiting A Korean Post-Marketing Surveillance Study On Pergoveris® (Follitropin Alfa + Lutropin Alfa)
Condition: Infertility
Intervention:
Outcome Measures: Frequency and severity of all adverse events regardless of the causal relationship to Pergoveris®;   Clinical pregnancy;   Percentage of patients with more than one follicle greater than 17mm on day of human chorionic gonadotrophin (HCG) administration
4 Recruiting The Luteal Phase After GnRHa Trigger - a Proof of Concept Study
Condition: Hormone Levels (Progesterone)
Interventions: Drug: hCG(r-hCG, Ovitrelle, Merck-Serono, Hellerup, Denmark) in the late follicular phase + luteal phase;   Drug: hCG(r-hCG, Ovitrelle,Merck-Serono, Hellerup, Denmark) in the follicular phase + luteal phase;   Drug: LH(r-LH,Luveris, Merck-Serono, Hellerup, Denmark) in the luteal phase;   Drug: vaginal progesterone(Crinone; Merck-Serono, Hellerup, Denmark) and estradiol(Estrofem; Novo Nordisk, Copenhagen, Denmark) in the luteal phase
Outcome Measure: Levels of progesterone in the mid-luteal phase.
5 Recruiting Phase 3 Study to Evaluate the Efficacy and Safety of Pergoveris® in Assisted Reproductive Technology (ESPART)
Condition: Infertility
Interventions: Drug: Pergoveris®;   Drug: GONAL-f®;   Drug: Recombinant human chorionic gonadotrophin (r-hCG)
Outcome Measures: Total number of retrieved oocytes;   Ongoing pregnancy rate;   Live birth rate;   Embryo implantation rate;   Clinical pregnancy rate;   Biochemical pregnancy rate
6 Unknown  Growth Hormone for Poor Responders in in Vitro Fertilization (IVF)
Condition: In Vitro Fertilization
Interventions: Drug: Growth Hormone;   Drug: Patch protocol
Outcome Measures: number of mature oocytes retrieved;   duration of stimulation;   gonadotropin requirements;   number of cumulus-oocyte complexes retrieved;   number of fertilized oocytes;   proportion of patients reaching embryo transfer;   implantation rate;   clinical pregnancy rate
7 Recruiting Growth Hormone in Poor Responders to IVF Trial
Condition: Infertility
Interventions: Drug: Saizen (Human Growth Hormone);   Drug: No Saizen Control (Standard IVF Protocol)
Outcome Measures: Oocyte yield;   Pregnancy rate

These studies may lead to new treatments and are adding insight into Luveris etiology and treatment.

A major focus of Luveris research is the development of new drugs and other treatment options. Studies seek to identify new drugs to treat various related disorders and to find safer, more effective doses for medications already being used. Other research is aimed at identifying receptors or drug targets.


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