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Methyldopa Medical Research Studies

Up-to-date List of Methyldopa Medical Research Studies

What Research is Being Done?

A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two main types of clinical studies: clinical trials (also called interventional studies) and observational studies. Following list includes both interventional and observational studies.

Latest Methyldopa Medical Research Studies

Rank Status Study
1 Recruiting Effect of Methyldopa on MHC Class II Antigen Presentation in Type 1 Diabetes
Condition: Diabetes Mellitus, Type 1
Intervention: Drug: Methyldopa
Outcome Measures: Inhibition of DQ8 Antigen Presentation;   Assessment of C-Peptide Changes;   Assessment of Insulin Dose and Hemoglobin A1c;   Tolerability of Methyldopa
2 Recruiting Oral Antihypertensive Regimens for Management of Hypertension in Pregnancy
Conditions: Hypertension in Pregnancy;   Preeclampsia
Interventions: Drug: Nifedipine;   Drug: Labetalol;   Drug: Methyldopa
Outcome Measures: Successful outcome;   number of hourly BP's in severe range
3 Recruiting Community Level Interventions for Pre-eclampsia
Conditions: Pre-eclampsia;   Hypertension, Pregnancy Induced
Interventions: Behavioral: Community Engagement;   Device: PIERS on the Move mHealth decision aid;   Drug: Magnesium Sulfate;   Drug: Methyldopa
Outcome Measures: Maternal or Perinatal death or morbidity;   Birth preparedness and complication readiness;   Facility births
4 Unknown  Cardiovascular and Autonomic Reactivity in Women With a History of Pre-eclampsia
Condition: Preeclampsia
Intervention: Drug: alpha Methyldopa
Outcome Measures: normalized plasma volume;   increased orthostatic tolerance;   normalized cardiovascular balance;   venous capacitance
5 Recruiting Treatment of Orthostatic Hypotension
Conditions: Autonomic Nervous System Diseases;   Orthostatic Hypotension;   Dopamine Beta-Hydroxylase Deficiency;   Orthostatic Intolerance
Interventions: Drug: droxidopa;   Drug: placebo;   Drug: alpha-Methyldopa;   Drug: carbidopa;   Drug: metyrosine;   Drug: levodopa;   Drug: atomoxetine;   Drug: metoclopramide
Outcome Measures: Change in blood pressure with standing;   length of time subject is able to stand
6 Unknown  Treatment Targets for Chronic Hypertension in Pregnancy
Conditions: Pregnancy Toxemia;   Hypertension;   Proteinuria
Interventions: Drug: Methyldopa;   Drug: labetalol;   Drug: nifedipine;   Drug: clonidine
Outcome Measures: The achievement of target blood pressure obtained at every six weeks visits: weeks 20, 26, 32 and 38;   The incidence of superimposed preeclampsia;   Gestational age;   Birth weight < 10th centile for gestational age;   Serious perinatal complications
7 Unknown  Anti-Hypertensive Treatment In Stable Pregnant Women With Severe Pre-Eclampsia (Metildopape)
Condition: Preeclampsia
Interventions: Drug: methildopa;   Drug: placebo
Outcome Measures: Arterial blood pressure stabilization after methildopa use;   Complications in stable pregnant women with severe preeclampsia after methildopa use
8 Unknown  Cardiovascular an Echocardiographic Assessment in Hypertension During Pregnancy
Condition: Pregnancy
Outcome Measures: Hypertension impact on cardiovascular echocardiographic parameters and obstetric parameters in pregnant women with or without treatment;   Primary outcome, Impact of alfa methyl dopa and labetolol on cardiovascular parameters in pregnant women

These studies may lead to new treatments and are adding insight into Methyldopa etiology and treatment.

A major focus of Methyldopa research is the development of new drugs and other treatment options. Studies seek to identify new drugs to treat various related disorders and to find safer, more effective doses for medications already being used. Other research is aimed at identifying receptors or drug targets.

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