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Mucinex Medical Research Studies

Up-to-date List of Mucinex Medical Research Studies

What Research is Being Done?

A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two main types of clinical studies: clinical trials (also called interventional studies) and observational studies. Following list includes both interventional and observational studies.

Latest Mucinex Medical Research Studies

Rank Status Study
1 Recruiting Comparison Between Oxomemazine, Guaifenesin and Potassium Iodate Versus Guaifenesin Monotherapy in Acute Cough Treatment
Condition: Cough
Interventions: Drug: Syrup of oxomemazine, guaifenesin and potassium iodate;   Drug: Syrup of guaifenesin
Outcome Measures: Reduction/improvement of cough symptoms;   Tolerance
2 Recruiting Single Dose Trial of Extended Release Combination Tablet Codeine and Guaifenesin
Condition: Cough
Interventions: Drug: Extended Release Codeine Phosaphate/Guaifenesin Tablet 30 mg/600 mg;   Drug: IR Codeine Phosphate/Guaifenesin 20 mg/400 mg
Outcome Measures: Serum Levels of Codeine and Guaifenesin;   Safety and Tolerability
3 Not yet recruiting Triac Trial in MCT8 Patients
Condition: Allan-Herndon-Dudley Syndrome
Intervention: Drug: Triac
Outcome Measures: serum thyroid function tests;   general clinical examination;   tissue-specific markers of thyroid state;   Motor function, using the Gross Motor Function Measure;   Cognitive function using the Bayley Scales of Infant Development III;   Adaptive behavior by the Vineland adaptive behavior scale
4 Recruiting The Effect of Oral Guaifenesin on Pediatric Chronic Rhinitis: A Pilot Study
Condition: Chronic Rhinitis
Interventions: Drug: Placebo;   Drug: Guaifenesin
Outcome Measures: Subjective nasal scoring;   Nasal Volume;   Nasal Secretion Collection
5 Recruiting Effects of Su-Huang Antitussive Capsule on Cough Variant Asthma
Condition: Asthma
Interventions: Drug: Su-Huang antitussive capsule;   Drug: Sugar pill
Outcome Measures: Day-time and night-time cough symptom total-score changes from baseline to visit 3;   Cough reflex sensitivity changes in 2 groups at baseline and visit 3. Cell differential changes in hypertonic saline induced sputum in 2 groups at baseline and visit3.
6 Unknown  Comparison Between Dexchlorpheniramine and Dexchlorpheniramine/Pseudoephedrine/Guaifenesin in Respiratory Infections
Condition: Viral Infections of the Upper Respiratory Tract
Interventions: Drug: Dexchlorpheniramine, pseudoephedrine, guaifenesin;   Drug: Dexchlorpheniramine
Outcome Measures: Symptoms frequency and intensity evaluated with a 5 point visual analogic scale (VAS);   Subjective evaluation of efficacy and tolerability graded as excellent, good, fair ou poor.
7 Unknown  Effectiveness and Safety of the of Guaifenesin, Doxylamine Succinate and Hydrochloride Etafedrine Syrup in Improvement of Symptoms Resulting From Acute Respiratory Infections.
Condition: Upper Airway Infections
Interventions: Drug: EMS Expectorant;   Other: Placebo
Outcome Measures: - Decrease in nasal secretion - Decrease in sneezing - Reduction of edema of the nasal mucosa - Decreased frequency of cough - Decrease the frequency of dyspnea - Reduction of nasal obstruction;   Will be assessed for safety by the incidence of adverse reactions
8 Unknown  Comparative Efficacy of the Suppository Versus Guaiacol Suppository Versus Guaifenesin Syrup in Pediatric Patients With Cough Due the Infectious Origin
Condition: Cough
Interventions: Drug: Guaiacol, eucalyptol, menthol and camphor suppository;   Drug: guaiacol suppository;   Drug: Guaifenesin syrup
Outcome Measures: Improvement of cough of infectious origin.;   Analysis of parameters for the improvement of infectious cough.
9 Recruiting Antitussive Effect of a Naturally Flavored Syrup Containing Diphenhydramine, Compared With Dextromethorphan and Placebo
Condition: Cough Reflex Sensitivity
Interventions: Drug: Phenylephrine;   Drug: Diphenhydramine;   Drug: Dextromethorphan
Outcome Measure: change in cough reflex sensitivity to capsaicin
10 Not yet recruiting Effect of Cyclodextrin on Sensory Nerve Activity: A Novel Anti-tussive Therapy
Condition: Cough
Intervention: Drug: cyclodextrin
Outcome Measure: Capsaicin Cough Challenge
11 Unknown  Postoperative Analgesia in Children After Propofol Anesthesia
Condition: Postoperative Pain
Intervention: Drug: Propofol
Outcome Measures: postoperative pain;   recovery time;   adverse effects
12 Recruiting A Double-blind, Placebo-controlled, Crossover Study to Assess the Effect of Aclidinium Bromide 400 μg Bid on COPD Symptoms and Sleep Quality After 3 Weeks of Treatment in Patients With Stable Moderate-to-severe Chronic Obstructive Pulmonary Disease (COPD)
Condition: Pulmonary Disease, Chronic Obstructive
Interventions: Drug: Aclidinium bromide;   Drug: Placebo
Outcome Measures: Change from baseline in normalised forced expiratory volume in one second (FEV1);   Adverse events
13 Recruiting Study of NMDA Antagonists and Neuropathic Pain
Condition: Neuropathic Pain
Interventions: Drug: Dextromethorphan (drug used like antitussive);   Drug: Memantine (drug used in Alzheimer's disease);   Drug: Placebo (lactose)
Outcome Measures: Measure of pain by numerical scale;   Patient Global Impression if Change (PGIC);   Leed's slip questionnaire;   Questionnaire of quality of life SF 36;   DN4 scale;   Neuropathic Pain Symptoms Inventory (NPSI);   Saint-Antoine questionnaire (QDSA);   HAD scale;   Questionnaire of identification of pain (QCD);   Evaluation of cognitive impact (Cantab, Cambridge)
14 Recruiting In Vivo Assessment of Hypoxia in Gastro-intestinal Cancer Using 18F-HX4-PET: an Optimization and Reproducibility Study
Conditions: Pancreatic Cancer;   Esophageal Cancer;   Rectal Cancer
Intervention: Drug: [F-18]HX4
Outcome Measures: Reproducibility of SUV measured with 18F-HX4 PET;   Optimal time frame between administration of 18F-HX4 and PET scan
15 Recruiting A Molecule Basic Study of Early Warning for New Pathogenic Risk of Ankylosing Spondylitis
Condition: Ankylosing Spondylitis
Interventions: Biological: MSC;   Drug: "celecoxib", "Celebrex®"
Outcome Measures: the proportion of patients which disease activity reaches ASAS(assessment in ankylosing Spondylitis)20 remission criteria;   BASDAI score comparing to baseline;   BASFI score comparing to baseline
16 Recruiting A Phase II Study to Assess Efficacy of Combined Treatment With Erlotinib (Tarceva) and Silybin-phytosome (Siliphos) in Patients With EGFR Mutant Lung Adenocarcinoma
Condition: Carcinoma, Non-Small-Cell Lung
Interventions: Drug: Erlotinib;   Dietary Supplement: Silybin-phytosome
Outcome Measures: Tumour response rate;   Safety assessment
17 Recruiting Safety and Efficacy of Exenatide as Monotherapy and Adjunctive Therapy to Oral Antidiabetic Agents in Adolescents With Type 2 Diabetes
Condition: Type 2 Diabetes
Interventions: Drug: placebo;   Drug: exenatide
Outcome Measures: The primary objective of this study is to test the hypothesis that glycemic control with exenatide is superior to that of placebo after 28 weeks of treatment in adolescent patients;   Exenatide 5 µg BID vs. Exenatide 10 µg BID vs. placebo to compare: • the proportion of patients achieving an HbA1c at endpoint of ≤7%, <7%, ≤6.5% and <6.5% • body weight • fasting serum glucose • self-monitored blood glucose
18 Unknown  Rabeprazole Based Sequential-Concommitant Hybrid Therapies for H. Pylori Infections
Condition: Helicobacter Pylori Infection
Interventions: Drug: RA5-RACM7;   Drug: RA3-RACM7;   Drug: RA7-RACM7
Outcome Measure: Eradication rate
19 Recruiting Comparison of the Eradications Rates of Sequential Therapy Versus Concomitant Therapy
Condition: Helicobacter Pylori Infection
Interventions: Drug: pantoprazole, amoxicillin, clarithromycin, metronidazole;   Drug: pantoprazole, amoxicillin, clarithromycin, metronidzole
Outcome Measure: Comparison of the eradications rates of sequential therapy versus concomitant therapy of treatment of Helicobacter pylori infection in Korea.
20 Recruiting The Role of the Tumor Microenvironment of Pancreatic Cancer to Predict Treatment Outcome
Condition: Pancreatic Cancer
Interventions: Drug: Gadobutrol;   Drug: [F-18]HX4;   Drug: Gemcitabine;   Radiation: Radiotherapy;   Procedure: Pancreaticoduodenectomy
Outcome Measures: Predictive value of pretreatment DWI, DCE-MRI, T2*, and 18F-HX4-PET/CT on overall survival in patients with pancreatic cancer treated with surgery and adjuvant chemotherapy or with neoadjuvant radiochemotherapy, surgery and adjuvant chemotherapy.;   Predictive value of pretreatment DWI, DCE-MRI, T2*, and 18F-HX4-PET/CT on recurrence free survival in patients with pancreatic cancer treated with surgery and adjuvant chemotherapy or with neoadjuvant radiochemotherapy, surgery and adjuvant chemotherapy.;   Predictive value of pretreatment DWI, DCE-MRI, T2*, and 18F-HX4-PET/CT on pathological response in patients with pancreatic cancer treated with neoadjuvant radiochemotherapy;   Predictive value of changes in DWI, DCE-MRI, T2*, and 18F-HX4-PET/CT parameters after radiochemotherapy on pathological response in patients with pancreatic cancer treated with neoadjuvant radiochemotherapy;   Predictive value of changes in DWI, DCE-MRI, T2*, and 18F-HX4-PET/CT parameters after radiochemotherapy on recurrence-free survival in patients with pancreatic cancer treated with neoadjuvant radiochemotherapy, surgery and adjuvant chemotherapy;   Immunohistochemically determined parameters of the tumor microenvironment assessed after resection of the pancreatic tumor to predict overall and recurrence-free survival;   Immunohistochemically determined parameters of the tumor microenvironment assessed in a pretreatment tumor biopsy to predict overall and recurrence-free survival

These studies may lead to new treatments and are adding insight into Mucinex etiology and treatment.

A major focus of Mucinex research is the development of new drugs and other treatment options. Studies seek to identify new drugs to treat various related disorders and to find safer, more effective doses for medications already being used. Other research is aimed at identifying receptors or drug targets.


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