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Myalgia Medical Research Studies

Up-to-date List of Myalgia Medical Research Studies

What Research is Being Done?

A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two main types of clinical studies: clinical trials (also called interventional studies) and observational studies. Following list includes both interventional and observational studies.

Latest Myalgia Medical Research Studies

Rank Status Study
1 Not yet recruiting Exploratory Study on the Use of Pregabalin for the Treatment of Taxol Related Arthralgia-MYALGIA
Conditions: Taxane;   Drug-related Side Effects and Adverse Reactions;   Pain;   Breast Cancer
Interventions: Drug: Pregabalin;   Drug: Placebo
Outcome Measures: Integrated Numeric Pain Scores and Rescue Analgesic Medication Requirement as calculated by the method proposed by Silverman et al (Silverman, O'Connor et al. 1993).;   Numeric Pain Score (NPS);   The additional number of hours spent in horizontal position (∆HHP**);   FACT-taxane score
2 Recruiting IV Ibuprofen for Post-Electroconvulsive Therapy MYALGIA
Condition: Depression
Interventions: Drug: Placebo infusion;   Drug: ibuprofen intravenous
Outcome Measures: Pre-treatment with intravenous ibuprofen will attenuate the incidence & severity of post ECT MYALGIAs;   Pre-treatment with IV ibuprofen will attenuate and decrease the severity of post ECT headache
3 Recruiting A Study Comparing the Efficacy and Safety of Orally Administered Ibuprofen and Placebo in Delayed Onset Muscle Soreness
Condition: Delayed Onset Muscle Soreness
Intervention: Drug: Acetaminophen 1000mg
Outcome Measures: SPID (Sum Pain Intensity Difference);   spontaneous muscle pain/soreness;   Muscle stiffness with movement;   Overall evaluation measures
4 Recruiting Evaluation Of Efficacy And Safety Of Norspan In Moderate To Severe Pain Due To Osteoarthritis, Rheumatoid Arthritis, Joint/Muscle Pain
Conditions: Osteoarthritis;   Rheumatoid Arthritis;   Lower Back Pain;   Joint Pain;   Muscle Pain
Intervention: Drug: Buprenorphine transdermal patch
Outcome Measures: Efficacy according to BS-11 pain score;   Secondary efficacy outcome;   Adverse events
5 Recruiting Effects of a Polyherbal Supplement on the Signs and Symptoms of Delayed Onset Muscle Soreness
Condition: Delayed Onset Muscle Soreness
Interventions: Dietary Supplement: Polyherbal capsule;   Dietary Supplement: Placebo capsule
Outcome Measures: Change from baseline in peak muscle strength on Day 2 of each test period after eccentric exercise.;   Change from baseline in peak muscle strength after eccentric exercise;   Change from baseline in pain assessment after eccentric exercise;   Change from baseline in flexibility after eccentric exercise;   Change from baseline in elbow girth (swelling) after eccentric exercise;   Change from baseline in muscle tenderness after eccentric exercise;   Change from baseline in creatinine kinase (CK) and C-reactive protein (CRP) levels after eccentric exercise
6 Available Effect of American Ginseng on Exercise-induced Muscle Soreness
Condition: Exercise-induced Muscle Soreness
Intervention: Dietary Supplement: Ginseng
Outcome Measure:
7 Recruiting Addition of Pudendal Blocks to Pelvic Floor Physical Therapy for the Treatment of Pelvic Floor Tension MYALGIA
Condition: Pelvic Floor Muscle Spasm
Interventions: Drug: Pudendal block;   Drug: Placebo
Outcome Measures: Visual analog pain score after 6 weekly injections;   Improvement in pelvic floor symptoms as assessed through standardized questionnaires
8 Recruiting An Investigator Initiated, Within-Subject, Proof of Concept Study to Assess the Analgesic Efficacy and Safety of Voltaren Gel (1% Diclofenac Sodium) Compared to Placebo in Subjects Experiencing Delayed Onset Muscle Soreness
Condition: Delayed Onset Muscle Soreness
Interventions: Drug: 1% diclofenac sodium gel;   Drug: Placebo
Outcome Measure: To assess analgesic efficacy of Topical Voltaren® gel compared to placebo
9 Unknown  Efficacy and Safety of Salonsip Compared to Sabiá Plaster
Conditions: Contusions;   Sprains;   MYALGIA;   Pain;   Tendonitis
Interventions: Drug: Salonsip plaster;   Drug: Sabia plaster
Outcome Measures: Likert Scales and Visual Analogue Scales;   Safety evaluation by adverse events relate.
10 Unknown  Study to Assess the Efficacy and Safety of Ibuprofen 50 mg/g Gel Compared to Profenid 25mg/g Gel
Conditions: Muscular Atrophy;   Sprains;   Tendonitis
Interventions: Drug: Ibuprofen;   Drug: Profenid
Outcome Measures: Clinical study evaluating the efficacy and safety of Ibuprofen 50mg / g gel in the treatment of patients with muscle pain, joint, or pain caused by sprains, contusions, tendinitis, or myofascial compared to Profenid ® 25mg / g gel. ";   Clinical study evaluating the tolerability of Ibuprofen 50mg / g gel in the treatment of patients with muscle pain, joint, or pain caused by sprains, contusions, tendinitis, or myofascial compared to Profenid ® 25mg / g gel. "
11 Recruiting Low Intensity Ultrasound Therapy for Upper Back Pain Relief
Condition: Muscle Spasm
Interventions: Device: Sam Ultrasonic Diathermy Device (Active Device);   Device: Sam Ultrasonic Diathermy Device (Placebo Device)
Outcome Measures: Change in pain on the visual analog scale (VAS);   Comparison of pain level using Global Rating of Change (GROC) scale.;   Change in trigger point depth
12 Recruiting Tumor Necrosis Factor-alpha Inhibition Using Etanercept in Chronic Fatigue Syndrome
Conditions: Chronic Fatigue Syndrome;   Myalgic Encephalomyelitis
Intervention: Drug: Etanercept
Outcome Measures: Symptom alleviation within 12 months follow-up, as compared to baseline, measured by standardized self-reports and quality of life schemes.;   Symptom alleviation, as compared to baseline, measured by standardized self-reports and quality of life schemes.
13 Not yet recruiting Comparing Intubating Conditions Using Succinylcholine or Rocuronium for Rigid Bronchoscopy
Conditions: Intubating Conditions;   Postoperative MYALGIA;   Patient Satisfaction
Interventions: Drug: Succinylcholine;   Drug: Rocuronium 0,3;   Drug: Rocuronium 0,6
Outcome Measures: Intubating Condition;   Postoperative MYALGIA
14 Recruiting Low Dose Mivacurium vs. Low Dose Succinylcholine for Rigid Bronchoscopy
Conditions: Intubating Conditions;   Performance With Respiratory Exercise Device;   Postoperative MYALGIA
Interventions: Drug: Succinylcholine;   Drug: Mivacurium
Outcome Measures: Intubating condition;   Postoperative MYALGIA;   postintervention performance with a expiration exercise device
15 Unknown  A Randomized, Double Blind, Placebo Controlled Trial L-carnitine and Piracetam in the Treatment of Weakness, Muscle Fatigue and Muscle Pain in the Postpoliomyelitis Syndrome
Condition: Postpoliomyelitis Syndrome
Interventions: Drug: L-carnitine and piracetam;   Drug: Placebo
Outcome Measures: Changes in Muscle Weakness;   Changes in fatigue;   Changes in muscle pain;   Changes in daytime sleepiness;   Changes in quality of life;   Changes in daily function;   Changes in depressive mood;   Changes in oxidative capacity in skeletal muscle;   Occurrence of adverse events
16 Unknown  Hood to Coast Injury Study
Condition: Pain
Interventions: Dietary Supplement: Tart Cherry Juice;   Dietary Supplement: Fruit juice
Outcome Measure: The administration of tart cherry juice will reduce the symptoms of exercise-induced muscle damage as measured by patients assessment of pain on a standard VAS.
17 Recruiting Antibiotic Treatment of Multiple Erythema Migrans
Condition: Multiple Erythema Migrans
Interventions: Drug: ceftriaxone;   Drug: doxycycline;   Other: erythema migrans patients treated with doxycycline
Outcome Measures: Objective sequelae and post-treatment subjective symptoms such as fatigue, malaise, arthralgias, headache, MYALGIAs, paresthesias, dizziness, or irritability in patients treated for multiple erythema migrans with ceftriaxone or doxycycline for 15 days.;   Comparison of subjective symptoms such as fatigue, malaise, arthralgias, headache, MYALGIAs, paresthesias, or irritability between patients treated with antibiotic for multiple erythema migrans and control subjects without a history of Lyme borreliosis.;   Objective sequelae and post-treatment subjective symptoms such as fatigue, malaise, arthralgias, headache, MYALGIAs, paresthesias, dizziness, or irritability in patients with solitary versus multiple erythema migrans after antibiotic treatment.
18 Unknown  Clinical Evaluation of QFlu Combo Test
Conditions: Cough;   MYALGIA;   Nasal Obstruction;   Sore Throat;   Headache;   Fatigue;   Fever
Intervention:
Outcome Measures: Sensitivity and specificity for drug resistance detection;   Sensitivity and Specificity of the Test for Influenza Diagnosis
19 Unknown  Effect of Propranolol on the Autonomic Nervous System and Muscle Pain
Conditions: Temporomandibular Joint Disorders;   Myofascial Temporomandibular Disorders
Interventions: Drug: Propranololhydrochlorid;   Drug: Placebo
Outcome Measures: Pain intensity;   Haemodynamic parameters
20 Unknown  Vitamin D Replacement in Statin-Induced Myopathy
Condition: HMG COA Reductase Inhibitor Adverse Reaction
Interventions: Drug: Vitamin D (Cholecalciferol );   Drug: Placebo
Outcome Measures: lack of need to stop statin medication due to MYALGIA;   reduction of visual analog pain score

These studies may lead to new treatments and are adding insight into Myalgia etiology and treatment.

A major focus of Myalgia research is the development of new drugs and other treatment options. Studies seek to identify new drugs to treat various related disorders and to find safer, more effective doses for medications already being used. Other research is aimed at identifying receptors or drug targets.


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