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Necitumumab Medical Research Studies

Up-to-date List of Necitumumab Medical Research Studies

What Research is Being Done?

A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two main types of clinical studies: clinical trials (also called interventional studies) and observational studies. Following list includes both interventional and observational studies.

Latest Necitumumab Medical Research Studies

Rank Status Study
1 Recruiting A Study of Necitumumab in the First-Line Treatment of Stage IV Squamous Non-Small Cell Lung Cancer (NSCLC)
Condition: Squamous Non-small Cell Lung Cancer
Interventions: Drug: Necitumumab;   Drug: Gemcitabine;   Drug: Cisplatin
Outcome Measures: Phase 1b: Number of Participants with Dose Limiting Toxicities (DLTs);   Phase 2: Overall Survival (OS);   Phase 2: Progression Free Survival (PFS);   Phase 1b: Number of Participants who Achieve Best Overall Tumor Response of Complete Response or Partial Response (Objective Tumor Response Rate [ORR]);   Phase 2: Number of Participants who Achieve Best Overall Tumor Response of Complete Response or Partial Response (Objective Tumor Response Rate [ORR]);   Phase 2: Time to Treatment Failure (TTF);   Phase 2: Change from Baseline in EuroQol 5-Dimensional Scale (EQ-5D);   Phase 2: Change from Baseline in Lung Cancer Symptom Scale (LCSS);   Phase 1b/2: Pharmacokinetics (PK): Maximum Concentration (Cmax) of Necitumumab;   Phase 1b: PK: Cmax of Gemcitabine and Cisplatin;   Phase 1b: PK: Area Under the Concentration Curve (AUC) of Necitumumab;   Phase 1b: PK: AUC of Gemcitabine and Cisplatin;   Phase 2: PK: Minimum Concentration (Ctrough) of Necitumumab;   Number of Participants with Anti Necitumumab Antibodies

These studies may lead to new treatments and are adding insight into Necitumumab etiology and treatment.

A major focus of Necitumumab research is the development of new drugs and other treatment options. Studies seek to identify new drugs to treat various related disorders and to find safer, more effective doses for medications already being used. Other research is aimed at identifying receptors or drug targets.


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