sponsored
PatientsVille.com Logo

PatientsVille

OMEPRAZOLE Medical Research Studies

Up-to-date List of OMEPRAZOLE Medical Research Studies

What Research is Being Done?

A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two main types of clinical studies: clinical trials (also called interventional studies) and observational studies. Following list includes both interventional and observational studies.

Latest OMEPRAZOLE Medical Research Studies

Rank Status Study
1 Recruiting Management of Myocardial Injury After Noncardiac Surgery Trial
Condition: Myocardial Injury After Noncardiac Surgery (MINS)
Interventions: Drug: Dabigatran;   Drug: Placebo (for Dabigatran);   Drug: Omeprazole;   Drug: Placebo (for Omeprazole)
Outcome Measures: Major vascular complication (for Dabigatran);   Major upper gastrointestinal complication (for Omeprazole);   Individual secondary outcomes for Dabigatran;   Upper gastrointestinal complication for Omeprazole;   Major vascular complication for Omeprazole;   Individual secondary outcomes for Omeprazole;   Safety outcomes for Dabigatran;   Safety outcomes for Omeprazole
2 Unknown  Comparison of Oral Rabeprazole vs. iv Omeprazole in Mild to Moderate Nonvariceal Upper Gastrointestinal Bleeding
Condition: Nonvariceal Upper Gastrointestinal Bleeding
Interventions: Drug: Intravenous Omeprazole;   Drug: Oral Rabeprazole
Outcome Measure: This study aims to compare the effect of three-day oral rabeprazole and iv Omeprazole on bleeding control in patients with mild to moderate non-variceal UGIB.
3 Not yet recruiting Omeprazole and Pantoprazole Antiplatelet Effect of Clopidogrel Clinical Trials(OPEN)
Condition: Acute Coronary Syndromes
Interventions: Drug: Omeprazole;   Drug: Pantoprazole
Outcome Measures: Platelet aggregation rate(AA 、ADP);   clinical adverse events
4 Recruiting Pilot Trial Of Omeprazole in Idiopathic Pulmonary Fibrosis (IPF)
Condition: Idiopathic Pulmonary Fibrosis
Interventions: Drug: Omeprazole;   Drug: Matched placebo
Outcome Measures: objectively measured cough frequency;   symptoms of cough;   reflux symptoms;   acid and non-acid reflux;   vital capacity (VC) & transfer factor for carbon monoxide (Tco);   6 minute walk distance;   assess amount of inflammation in lung;   lung infection rate;   adverse events rate
5 Recruiting Comparison of the Gastric Acid Suppressive Effects of EsOmeprazole and Generic Omeprazole
Condition: Gastric Acid
Interventions: Drug: EsOmeprazole first;   Drug: Generic Omeprazole first
Outcome Measures: Median intragastric pH and percentage of time that intragastric pH is above 4;   Nocturnal acid breakthrough, defined as at least 60 continuous minutes of intragastric pH below 4 occurring between 10pm and 6 am and adverse events
6 Recruiting Gastroesophageal Reflux Treatment in Scleroderma
Conditions: Gastroesophageal Reflux Disease;   Systemic Sclerosis;   Scleroderma
Interventions: Drug: Alginic acid;   Drug: placebo (for domperidone);   Drug: Domperidone;   Drug: placebo (of alginic acid)
Outcome Measures: Changing severity of heart burn and regurgitation of SSc related Omeprazole resistant GERD evaluated by visual analogue score (VAS);   changing of frequency of symptoms in SSc related Omeprazole resistant GERD evaluated by frequency scale for the symptoms of GERD (FSSG) and the quality of life which is evaluated by EQ-5DTM (by EuroQol Group);   the prevalence of Omeprazole-resistant GERD in SSc after 4 weeks treatment with Omeprazole
7 Unknown  Impact of Omeprazole and Fluvoxamine on Platelet Response to Clopidogrel
Condition: Drug Interaction of Clopidogrel
Interventions: Drug: Omeprazole;   Drug: fluvoxamine;   Drug: placebo
Outcome Measure: platlet reactivity in response to clopidogrel
8 Recruiting Compliance With Antidepressant Medication in Treatment of Functional Dyspepsia
Conditions: Dyspepsia;   Compliance;   Depression
Interventions: Drug: Omeprazole;   Drug: Flupentixol and Melitracen Tablets(for dyspepsia symptoms) + Omeprazole;   Drug: Flupentixol and Melitracen Tablets(for depression symptoms) + Omeprazole;   Drug: Flupentixol and Melitracen Tablets(without explanation) + Omeprazole
Outcome Measures: compliance of antidepressant medication;   dyspepsia symptom questionnaire;   psychiatric symptom on Hospital Anxiety and Depression Scale;   quality of life rating;   adverse reaction
9 Unknown  Evaluation of Omeprazole Effect on Glaucoma
Condition: Glaucoma
Interventions: Drug: Omeprazole;   Drug: Placebo
Outcome Measure:
10 Not yet recruiting "Pharmacodynamic Comparison of Omeprazole Versus Pantoprazole on Platelet Reactivity in Patients With Acute Coronary Syndromes on Dual Antiplatelet Therapy With New P2Y12 Inhibitors" -Trial dOPPLER-
Condition: Coronary Artery Disease
Interventions: Drug: Pantoprazole,;   Drug: Omeprazole
Outcome Measures: Assessment of platelet reaction units;   Frequency of high platelet reactivity
11 Recruiting Melatonin Associated to Acid Inhibition for Chemoprevention in Barret Esophagus: a Pilot Study
Condition: Barrett's Esophagus
Interventions: Drug: Omeprazole;   Drug: Melatonin
Outcome Measures: Oxidative stress;   Biological markers of diseases progression;   The presence of DNA anomalies (tetraploidy and aneuploidy.
12 Recruiting Rectal and Oral Omeprazole Treatment of Reflux Disease in Infants.
Conditions: Gastroesophageal Reflux;   Esophageal Atresia;   Hernia, Diaphragmatic
Intervention: Drug: Omeprazole suppository
Outcome Measures: Therapeutic efficacy;   Intragastric pH, Pharmacokinetic parameters, PK-PD-relation,;   Pharmacogenetic parameters
13 Recruiting CYP2C19 Genotype Predictor of Gastric Acid Suppression
Condition: Esophagitis
Intervention: Drug: Omeprazole
Outcome Measures: The correlation specific to CYP2C19 genotype with gastric acid suppression by Omeprazole.;   To assess patients gastrointestinal symptoms, in patients with EoE by means of standard validated questionnaires
14 Unknown  Role of CYP2C19 Polymorphism in the Drug Interaction Between Clopidogrel and Omeprazole
Condition: Coronary Artery Disease
Intervention:
Outcome Measures: To test whether concomitant administration of Omeprazole will decrease the platelet inhibitory properties of clopidogrel in subjects with loss of function (LOF) mutation of CYP2C19 (known as *2 and *3).;   To test whether concomitant administration of Omeprazole will decrease the conversion of clopidogrel to its active metabolite in subjects with loss of function (LOF) mutation of CYP2C19 (known as *2 and *3).
15 Not yet recruiting Evaluation of the Efficacy in Decreasing Iron Absorption in Patients With Congenital Dyserythropoietic Anemia Type I by Treatment With LOSEC
Condition: CDA Type I
Intervention: Drug: Omeprazole
Outcome Measure: evaluate number of adverse effects per patient treated with LOSEC + levels of iron, ferritin,complete blood count and chemistry panel.
16 Unknown  Platelet Inhibitory Effect of Clopidogrel in Patients Treated With Omeprazole, Pantoprazole, or Famotidine
Conditions: Coronary Heart Disease;   GI Bleeding
Intervention: Drug: PPI Platelet Inhibitory
Outcome Measure: Platelet function as assessed by a CPA system
17 Not yet recruiting Laryngomalacia Study
Condition: Laryngomalacia
Interventions: Drug: Omeprazole;   Drug: Placebo
Outcome Measures: Laryngomalacia Symptom Score;   Caring For a Child with Laryngomalacia Family Impact Questionnaire;   Revised Infant Gastro-Esophageal Reflux Questionnaire;   Reflux Finding Score;   End of treatment 24-hour double-probe pH monitoring;   Weight
18 Unknown  Assessment of Zegerid on Esophageal pH in Patients With Barrett's Esophagus
Conditions: Barrett Esophagus;   Gastroesophageal Reflux
Interventions: Drug: Zegerid (proton pump inhibitor);   Procedure: Bravo pH monitoring
Outcome Measures: Control of esophageal pH;   Control of GERD symptoms
19 Not yet recruiting The Effect of NSAIDs After a Rotator Cuff Repair Surgery.
Condition: Rotator Cuff Tear
Interventions: Procedure: Rotator cuff repair;   Drug: Ibuprofen, Hydrocodone/Acetaminophen, Omeprazole;   Drug: Hydrocodone/Acetaminophen
Outcome Measures: American Shoulder and Elbow Surgeons (ASES) Shoulder Score;   Ultrasound evaluation of retear rate
20 Not yet recruiting Placebo In Chronic Pain
Condition: Chronic Back Pain
Interventions: Drug: Naproxen;   Drug: Placebo;   Drug: Omeprazole
Outcome Measure: VAS pain scale

These studies may lead to new treatments and are adding insight into OMEPRAZOLE etiology and treatment.

A major focus of OMEPRAZOLE research is the development of new drugs and other treatment options. Studies seek to identify new drugs to treat various related disorders and to find safer, more effective doses for medications already being used. Other research is aimed at identifying receptors or drug targets.


Discuss OMEPRAZOLE