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Ortho-cept Medical Research Studies

Up-to-date List of Ortho-cept Medical Research Studies

What Research is Being Done?

A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two main types of clinical studies: clinical trials (also called interventional studies) and observational studies. Following list includes both interventional and observational studies.

Latest Ortho-cept Medical Research Studies

Rank Status Study
1 Not yet recruiting Location of Lower Extremity Deep Vein Thrombosis by Emergency Physicians Using Portable Compression Ultrasonography
Condition: Deep Vein Thrombosis
Interventions: Procedure: portable venous compression ultrasonography;   Procedure: venous compress ultrasonography;   Procedure: Doppler ultrasound of the lower limbs
Outcome Measures: Diagnosis of Deep Vein thrombosis by portable ultrasound: yes/no;   Diagnosis of Deep Vein thrombosis by doppler ultrasound: yes/no;   Diagnosis of Deep Vein thrombosis by classic ultrasound: yes/no;   Wells score
2 Recruiting The Designer D-dimer Deep Vein Thrombosis Diagnosis (4D) Study
Condition: Suspected Deep Vein Thrombosis
Intervention:
Outcome Measures: Confirmed symptomatic proximal Deep Vein Thrombosis;   Clinical Pretest Probability/ D-dimer/ Compression Ultrasound subgroups;   Death
3 Unknown  Residual Vein Thrombosis and the Optimal Duration of Low Molecular Weight Heparin in Cancer Patients With Deep Vein Thrombosis
Conditions: Deep Vein Thrombosis;   Cancer
Intervention: Drug: low molecular weight heparin
Outcome Measures: Recurrent Deep Vein Thrombosis and/or Pulmonary Embolism;   Minor bleeding;   Death due to cancer
4 Unknown  Rosuvastatin for Preventing Deep Vein Thrombosis
Conditions: Deep Vein Thrombosis;   Venous;   Thrombosis;   Prevention
Interventions: Drug: Rosuvastatin 20mg/d for 14days;   Drug: enoxaparin only
Outcome Measures: Development of Deep Vein thrombosis diagnosed and confirmed by CT angiography at lower extremities;   D-dimer, lipid panel (Total cholesterol, TG, HDL, LDL), hsCRP, CK, transaminase, ALP
5 Unknown  Point of Care Ultrasound (US) Versus Detailed Radiology US for Deep Vein Thrombosis (DVT)
Condition: Deep Vein Thrombosis
Intervention:
Outcome Measures: The agreement between physician performed ultrasound and formal duplex ultrasonography for detection of proximal Deep Vein thrombosis.;   Subgroup analysis: location of thrombus (proximal or distal);   Subgroup analysis: number of days in the hospital prior to exam;   Subgroup analysis: body mass index (BMI);   Subgroup analysis: weight gain from admission to the time of the exam;   Subgroup analysis: training level of examiner;   Subgroup analysis: difficulty of exam;   Subgroup analysis: specific examiner;   Subgroup analysis: presence or absence of calf vein thrombosis;   Subgroup analysis: presence or absence of pulmonary embolism;   Subgroup analysis: DVT location;   Subgroup analysis: calf vein thrombosis
6 Not yet recruiting The Impact of Laparoscopic Versus Open Surgeries on the Incidence of Postoperative Deep Vein Thrombosis in Patients With Gastrointestinal Malignancy ---A Cohort Study
Condition: Deep Vein Thrombosis
Interventions: Device: laparoscopic surgery;   Device: open surgery
Outcome Measures: the incidence of DVT;   concentration of plasma D - dimer 2;   time to basic recovery;   incidence of lung infection;   incidence of incision infection
7 Not yet recruiting General Practitioner-performed Compression Ultrasound for Deep Vein Thrombosis
Condition: Deep Vein Thrombosis
Intervention: Other: compression ultrasonography
Outcome Measures: Diagnostic accuracy of General Practitioner in performing CUS for the diagnosis of DVT;   Precision of CUS performed by General Practitioner for the diagnosis of DVT
8 Recruiting Whole-leg Ultrasound in Pregnant Patients
Condition: Deep Vein Thrombosis
Intervention: Other: Whole-leg compression ultrasound
Outcome Measures: Symptomatic VTE;   Isolated iliac DVT
9 Recruiting Randomized Controlled Trial of Anticoagulation vs. Placebo for a First Symptomatic Isolated Distal Deep-vein Thrombosis (IDDVT)
Condition: Distal (Calf) Deep-vein Thrombosis
Interventions: Drug: nadroparine calcium;   Drug: Placebo
Outcome Measures: Composite of rate of extension of distal DVT to proximal Deep Veins (includes ipsilateral extension or new contralateral proximal DVT) or symptomatic PE at 6 weeks;   Rate of post-thrombotic syndrome (PTS);   Individual components of the composite endpoint: distal DVT extension to proximal veins at 6 weeks and 90 days; PE at 6 weeks and 90 days;   Major bleeding at 6 weeks and 90 days;   Death at 6 weeks and 90 days;   Serious adverse events at 6 weeks and 90 days;   Generic and venous disease-specific Quality of Life scores;   PTS severity category
10 Not yet recruiting Osteopathic Treatment and Deep Vein Thrombosis (DVT)
Condition: Deep Vein Thrombosis (DVT)
Intervention: Other: Osteopathic Treatment
Outcome Measures: Swelling;   Pain
11 Recruiting Left Rule, D-Dimer Measurement and Complete Ultrasonography to Rule Out Deep Vein Thrombosis During Pregnancy.
Conditions: Pregnancy;   Deep Vein Thrombosis
Intervention: Other: Left rule, D-dimer measurement and complete ultrasonography in pregnant women.
Outcome Measures: The main outcome will be the number of thromboembolic recurrent events (DVT, PE, death attributable to venous thromboembolic disease) documented during the three-month follow-up in the patients left untreated on the basis of a normal diagnostic strategy.;   Prospective evaluation of the diagnostic performances of the LEFt rule.;   Prospective evaluation of D-dimer measurement to rule out DVT in pregnant women.
12 Recruiting Efficacy of Bemiparin Versus Enoxaparin in the Treatment of DVT
Condition: Deep Vein Thrombosis
Interventions: Drug: Bemiparin sodium;   Drug: enoxaparin sodium
Outcome Measures: Percentage of patients with an improvement in thrombotic burden at Visit 3;   Incidence of symptomatic venous thromboembolic events (VTE)
13 Recruiting Simplification of the Diagnosis of Deep Vein Thrombosis
Condition: Deep Venous Thrombosis
Intervention: Other: Extensive search for isolated calf DVT
Outcome Measures: Safety of withdrawing anticoagulation from patients labeled as not having DVT on the basis of a one-day examination;   The rate of isolated calf vein thrombi
14 Not yet recruiting Advanced Diagnostic Management of Suspected Recurrent Ipsilateral DVT With MRDTI
Condition: Deep Vein Thrombosis
Intervention: Other: MRDTI
Outcome Measures: 3-month incidence of recurrent VTE in non-treated patients;   3-month incidence of recurrent VTE in patients with normal D-dimer test and unlikely clinical probability according to the Wells clinical decision rule for DVT
15 Unknown  Re-STOP DVT: Reload of High Dose Atorvastatin for Preventing Deep Vein Thrombosis in Statin Users
Conditions: Thrombosis;   Prevention;   Surgery
Interventions: Drug: High dose Atorvastatin+enoxaparin;   Drug: Enoxaparin
Outcome Measures: Development of Deep Vein thrombosis diagnosed and confirmed by CT angiography at lower extremities;   D-dimer, lipid panel (Total cholesterol, TG, HDL, LDL), hsCRP, CK, transaminase, ALP
16 Unknown  The Diagnosis of Occult Deep Vein Thrombosis of the Lower Extremities in Patients Presenting With Hypoxia
Condition: Hypoxia
Intervention: Device: Ultrasound compression of femoral and popliteal veins
Outcome Measure:
17 Unknown  Diagnostic Approach of Deep Vein Thrombosis in Primary Care
Condition: Thrombosis
Intervention: Other: D Dimer and ultrasonography
Outcome Measure:
18 Recruiting VTEval Project - A Prospective Cohort Study to Evaluate Diagnosis, Management and Outcome in Individuals With Venous Thromboembolism
Conditions: Venous Thromboembolism (VTE);   Deep Vein Thrombosis (DVT);   Pulmonary Embolism (PE)
Intervention:
Outcome Measures: Mortality;   Symptomatic venous thromboembolism;   Hemodynamic instability;   Use of mechanical ventilation;   Admission to Intensive Care Unit (ICU);   Recurrence of acute PE;   Cardiac dysfunction or heart failure;   Pneumonia;   Symptomatic and/or asymptomatic DVT;   Major bleeding;   Clinically relevant non-major bleedings;   Diagnostic of a previously unknown malignancy;   Length of hospitalization;   Implantation of vena cava filter;   Thrombolytic treatment;   Interventional treatment;   Surgery;   Overall mortality;   PE-related death;   Development or recurrence of clinical symptomatic PE/DVT;   Asymptomatic DVT;   Chronic venous insufficiency (CVI);   Post-thrombotic Syndrome (PTS);   Development of cardiac dysfunction or heart failure;   Development of pulmonary hypertension;   Respiratory dysfunction;   Net clinical outcome (NCO);   O2 home treatment;   Pulmonary vasoactive drugs;   Development of Chronic Thromboembolic Pulmonary Hypertension (CTEPH);   Hospitalization;   Length of stay in Hospital due to VTE;   Major adverse cardiac and cerebrovascular event (MACCE);   Cardiovascular event;   Cerebrovascular event
19 Recruiting Measurement of D-Dimer Levels in Patients With Confirmed Deep Vein Thrombosis
Condition: Deep Venous Thrombosis
Intervention:
Outcome Measures: STA Liatest DDi results in DVT positive cases;   STA Liatest DDi Versus STA Liatest DDi Plus
20 Recruiting Prevention of Recurrence After Thrombolysis in Acute Iliofemoral Venous Thrombosis (PRAIS) Study
Condition: Ileofemoral Deep Vein Thrombosis
Interventions: Drug: rivaroxaban;   Drug: Warfarin
Outcome Measures: recurrence rate;   vascular events

These studies may lead to new treatments and are adding insight into Ortho-cept etiology and treatment.

A major focus of Ortho-cept research is the development of new drugs and other treatment options. Studies seek to identify new drugs to treat various related disorders and to find safer, more effective doses for medications already being used. Other research is aimed at identifying receptors or drug targets.


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