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POD Medical Research Studies

Up-to-date List of POD Medical Research Studies

What Research is Being Done?

A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two main types of clinical studies: clinical trials (also called interventional studies) and observational studies. Following list includes both interventional and observational studies.

Latest POD Medical Research Studies

Rank Status Study
1 Unknown  Depodur vs Fentanyl Infusion for Post-C/S Analgesia
Condition: Analgesia
Interventions: Drug: Depodur;   Drug: Fentanyl
Outcome Measures: Degree of analgesia (measured on a 10-point scale);   Frequency of minor side effects, such as pruritis or nausea.
2 Unknown  Combination of Peripheral Nerve Block and Depodur in Total Knee Joint Replacement
Condition: Arthroplasty, Replacement, Knee
Interventions: Drug: Depodur;   Procedure: sciatic nerve block
Outcome Measures: Postoperative Pain;   Time Required for Placement of Block;   Time to first use of rescue analgesia and PCA;   Total opioid consumption;   Degree of knee flexion (Range of motion);   Day of first ambulation;   Number of days required to achieve a 110° knee flexion;   Number of days of hospitalization;   Need for manipulation of knee joint under general anesthesia;   Secondary effects: nausea and vomiting, pruritus, supplemental oxygen, urinary catheterization;   Satisfaction score
3 Unknown  Clinical Study of Depodur Efficacy in Decreasing Post Operative Pain After Off Pump Coronary Artery Bypass Grafting (OP-CABG)
Condition: Pain, Postoperative
Intervention: Drug: Depodur vs. traditional management
Outcome Measure: Comparison of pain (Visual Analog Scale), post-op morphine usage, and side effects between the two study groups
4 Unknown  Extended-release Epidural Morphine for Acute Post-operative Analgesia Following Selective Dorsal Rhizotomy in Children
Condition: Spastic Cerebral Palsy
Interventions: Drug: Extended-release Epidural morphine (EREM) 80;   Drug: Extended-release Epidural Morphine (EREM) 120;   Drug: Control: Saline
Outcome Measures: Quantity of fentanyl administered;   Adequacy of analgesia as judged by age-adjusted pain scales.;   Incidence of respiratory depression;   Hemodynamic instability;   Rate of CSF leak;   Rate of infection;   Urinary retention;   Nausea and/or vomiting;   Pruritis
5 Unknown  The Use of Intraoperative Intrathecal Morphine Versus Epidural Extended Release Morphine for Postoperative Pain Control in Pediatric Patients Undergoing Posterior Spinal Fusion
Conditions: Pain Management;   Spinal Fusion;   Scoliosis
Intervention: Drug: Depodur
Outcome Measure: Objective data to analyze the primary outcomes of Time to first post-operative opioid-analgesic administration and Total opioid requirements during the first 48 hours after surgery
6 Unknown  Low Dose Extended-release Epidural and Lumbar Plexus Block Compared to Lumbar Plexus Block for Total Hip Resurfacing
Condition: Hip Arthroplasty
Interventions: Drug: Extended Release Epidural Morphine (EREM);   Drug: Placebo
Outcome Measures: Length of hospital stay after surgery;   Total opioid consumption;   Patient satisfaction score;   Verbal pain scores;   Distance walked

These studies may lead to new treatments and are adding insight into POD etiology and treatment.

A major focus of POD research is the development of new drugs and other treatment options. Studies seek to identify new drugs to treat various related disorders and to find safer, more effective doses for medications already being used. Other research is aimed at identifying receptors or drug targets.

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