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Pain Of Skin Medical Research Studies

Up-to-date List of Pain Of Skin Medical Research Studies

What Research is Being Done?

A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two main types of clinical studies: clinical trials (also called interventional studies) and observational studies. Following list includes both interventional and observational studies.

Latest Pain Of Skin Medical Research Studies

Rank Status Study
1 Recruiting Actinic Keratosis Study
Condition: Actinic Keratosis
Interventions: Drug: 5-fluorouracil 5% cream;   Drug: Calcipotriol 0.005% ointment;   Drug: Vaseline
Outcome Measures: percentage of change in the number of actinic keratoses from baseline;   complete and partial (>75%) clearance of actinic keratoses;   Composite score of erythema, itching and skin pain after topical 5-fluorouracil+calcipotriol vs. 5-fluorouracil alone treatment of actinic keratoses;   Induction of TSLP expression in keratinocytes by calcipotriol;   differences in response to topical 5-fluorouracil+calcipotriol vs. 5-fluorouracil alone between the four anatomical sites
2 Recruiting Postoperative Pain and Skin Closure Methods After Cesarean Section
Condition: Pregnancy
Interventions: Procedure: Insorb staples skin closure;   Procedure: Monocryl skin closure;   Procedure: Vicryl skin closure
Outcome Measures: Intravenous and analgesic use.;   Daily subjective pain score while hospitalized;   6 week postoperative subjective pain score;   Scar cosmetic score 6 weeks post-operatively.;   Wound complications;   Length of hospital stay
3 Unknown  The Effect of Medical Clowns and Topical Anesthetic Cream on Pain and Anxiety in Children Undergoing Allergy Skin Tests
Conditions: Anxiety Disorder;   Allergic Skin Reaction
Interventions: Biological: Cream of Macrogol cetostearyl ethers;   Drug: Cream of Lidocaine 2.5 %.and Prilocaine 2.5 %;   Behavioral: Care and treatment from a medical clown
Outcome Measures: The level of anxiety experienced by children undergoing allergy skin tests and receiving application of local anesthetic cream and/or care and treatment from medical clowns;   Severity of pain experienced by these children
4 Unknown  Evaluation of Pain Reduction in the Administration of Saline Injections by the Usage of Pneumatic Skin Flattening
Condition: Healthy
Interventions: Procedure: Saline Injection;   Device: Pneumatic Skin Flattening (PSF)
Outcome Measure: VAS pain scaling differences between saline injection with PSF and without PSF
5 Recruiting Comparison of the Skin Conductance Values and Patient Pain Scores During Minor Procedures in the ICU
Condition: Pain
Intervention: Device: Skin Conductance Monitor
Outcome Measure: Sensitivity and specificity with a confidence interval
6 Recruiting Impact of Applying a Bandage Skin Hydrogel on the Pains of the Head and Neck in Patients With Cancer of Head and Neck Treated With Radiotherapy
Condition: Head and Neck Cancer
Interventions: Device: bandage skin Hydrotac®;   Drug: Ialuset®
Outcome Measures: Impact of applying a bandage hydrogel skin on head and neck pains;   Evaluating the terms of issue of the treatment
7 Recruiting Prediction of Chronic Pain by the Pain Monitor
Condition: Surgery
Intervention: Device: Pain Monitor
Outcome Measures: Prediction of chronic pain;   Prediction of the postoperative pain;   Prediction of the postoperative antalgic requirement;   Prediction of the postoperative antalgic requirement by the genetic study;   Effect of remifentanil on skin conductance
8 Not yet recruiting Study of Use of Synera for Pain During Local Skin Infiltration With Lidocaine Before Epidural Placement
Conditions: Pain;   Anxiety
Intervention: Drug: Synera
Outcome Measures: Rating of pain intensity upon lidocaine infiltration;   Subject anxiety
9 Recruiting Efficacy and Safety of Silk Fibroin With Bioactive Coating Layer Dressing
Conditions: Late Complication From Skin Graft;   Infection of Skin Donor Site;   Impaired Wound Healing;   Pain, Intractable;   Transepidermal Water Loss (TEWL)
Interventions: Device: Silk fibroin with bioactive coating layer dressing;   Device: Bactigras wound dressing
Outcome Measures: Clinical efficacy of of wound dressing containing silk fibroin with bioactive coating layer dressing in the treatment of split-thickness skin graft donor sites;   Clinical safety of wound dressing containing silk fibroin with bioactive coating layer dressing in the treatment of split-thickness skin graft donor sites
10 Recruiting Clinical Study on Silk Sericin Wound Dressing for Split-thickness Skin Graft Donor Sites Treatment
Conditions: Late Complication From Skin Graft;   Infection of Skin Donor Site;   Impaired Wound Healing;   Pain, Intractable
Intervention: Device: Sericin scaffold
Outcome Measures: Clinical efficacy of wound dressing containing silk sericin for split-thickness skin graft donor site treatment;   Clinical safety of wound dressing containing silk sericin for split-thickness skin graft donor site treatment
11 Unknown  Use of Topical Lidocaine to Reduce Pain in Patients With Diabetic Neuropathy
Condition: Diabetic Peripheral Neuropathy
Intervention: Other: Skin biopsy
Outcome Measure: To determine if the lidocaine patch provides therapeutic benefit to patients with painful diabetic neuropathy.
12 Recruiting Reduction of Pain Caused by Biologic Drugs in Psoriasis
Conditions: Psoriasis;   Pain
Interventions: Other: Heating Pack;   Other: Ice pack
Outcome Measure: Reduction of pain measured on a visual analogue scale
13 Recruiting Lidocaine For Treatment of Post-operative Pain From Donor Sites Following Burn Injury.
Condition: Pain
Interventions: Drug: Lidocaine;   Drug: Placebo
Outcome Measure: Pain improvement
14 Recruiting Determination of a Proper Needle Entry Point; Effects of Skin Compression With an Indicator on Radiation Exposure Time of Fluoroscopically Guided Transforaminal Epidural Block in Obese Patients
Condition: Low Back Pain Due to Spinal Nerve Compression
Intervention: Procedure: skin compression
Outcome Measures: Total radiation exposure time;   The number of the needle readjustments
15 Recruiting The Role of Timing of Dexamethasone Administration on Pain Scores and Quality of Recovery in Cesarean Section.
Condition: Pregnancy
Interventions: Drug: Control;   Drug: Intervention
Outcome Measures: Postoperative Pain using visual analogue score.;   Number of episodes of Nausea and Vomiting
16 Unknown  Measurement of Stress During Anesthesia With "Pain Detector" on Patients Receiving Atropine
Conditions: Hemorrhoids;   Fissure in Ano
Interventions: Drug: Administration of 0,7 mg of atropine;   Device: Measurement of skin conductance with Pain detector
Outcome Measure: Number of skin conductance fluctuations
17 Unknown  Local Anesthesia and Tuberculin Skin Test in Infants and Children
Condition: Tuberculosis
Intervention: Drug: lidocaine / Prilocaine
Outcome Measures: Measurement of tuberculin skin tests reaction performed with and without;   local anaesthesia, in a child (intra subject reproducibility);   influence of local anaesthesia use, on tuberculin skin test interpretation;   between observer reproducibility;   pain evaluation in child over 5 years of age between tuberculin skin tests performed with and without local anaesthesia;   relationship between local anaesthesia use and failure to perform a correct intradermal injection;   local tolerance to lidocaine / prilocaine
18 Recruiting Comparison of Staples Versus Prolene Suture for Skin Closure at Cesarean Delivery
Conditions: Pregnancy;   Cesarean Section
Interventions: Procedure: Staples;   Procedure: Prolene non-absorbable sutures;   Procedure: Absorbable Sutures
Outcome Measures: Pain levels during the post-operative hospitalization period and at time of staple or suture removal.;   Pain at 6 weeks post op;   Wound complications (infection, seroma/hematoma, dehiscence);   Patient satisfaction at post operative day 3, 4 and 6 weeks;   Operative room time;   Removal time;   Overall cosmesis;   Overall patient satisfaction
19 Unknown  In Children, Does Using a Synera Patch Decrease Pain When Injecting Propofol at Anesthesia Induction?
Condition: Pain on Propofol IV Injection
Interventions: Device: lidocaine/tetracaine transdermal patch (NDC 43469-864-01);   Drug: Gebauer's Ethyl Chloride
Outcome Measures: Number of children in each group who do not feel pain or have mild pain on propofol injection.;   Pain intensity
20 Unknown  Immunolabeling Evaluation of Five Selected Markers in Skin Biopsies of Patients With Postherpetic Neuralgia and Healthy Controls
Conditions: Postherpetic Neuralgia;   Healthy Age/Gender Matched Volunteers
Intervention: Other: skin biopsy
Outcome Measure: use of genetic data to enhance the search for targeted therapeutic approaches to chronic pain management

These studies may lead to new treatments and are adding insight into Pain Of Skin etiology and treatment.

A major focus of Pain Of Skin research is the development of new drugs and other treatment options. Studies seek to identify new drugs to treat various related disorders and to find safer, more effective doses for medications already being used. Other research is aimed at identifying receptors or drug targets.


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