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Pco2 Increased Medical Research Studies

Up-to-date List of Pco2 Increased Medical Research Studies

What Research is Being Done?

A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two main types of clinical studies: clinical trials (also called interventional studies) and observational studies. Following list includes both interventional and observational studies.

Latest Pco2 Increased Medical Research Studies

Rank Status Study
1 Unknown  Comparison of Two Methods of Continuous Positive Airway Pressure (CPAP) to Support Successful Extubation of Infants of Birth Weights ≤ 1500 Grams (C2CPAP)
Conditions: Premature Birth;   Respiratory Insufficiency
Interventions: Device: Infant Flow System;   Device: Bubble CPAP
Outcome Measures: failure of extubation as defined by the following: pH < 7.25 and PCO2 > 65 (or an increase of 15 mmHg from pre-extubation), a sustained (> 1 hour) increase in FiO2 of .15 (as compared to pre-extubation) or significant apno;   reintubation;   length of time in days on CPAP;   corrected gestational age at cessation of CPAP;   average weight gain on CPAP;   assessment of pain will
2 Recruiting Respiratory Physiology in Children With Febrile Seizures.
Conditions: Febrile Illness in Children;   Seizures, Febrile
Intervention:
Outcome Measures: Change of transcutaneous pCO2 per change of body temperature [mmHg/degree C];   Change of respiratory rate per change of body temperature [1/sec * degree C];   Change of transcutaneous pCO2 per change of respiratory rate [mmHg * sec]
3 Recruiting Alveolar Recruitment Maneuver During Cesarean Section Improves Lung Compliance
Conditions: Decreased Lung Compliance;   Hypoxia;   Hypercapnia;   Atelectasis;   Pneumonia
Intervention: Procedure: Alveolar Recruitment maneuver
Outcome Measures: Lung Compliance change measured as volume difference/pressure difference (dv/dp) or ml/cmH2O is being assessed;   Oxygenation change is being assessed measured as PO2 (mmHg) and O2 Saturation (SPO2);   Gas exchange change is being assessed measured as PCO2 (mmHg) and PH.;   Pulmonary complications
4 Recruiting High Frequency Oscillatory Ventilation Combined With Intermittent Sigh Breaths: Effects on Blood Oxygenation and Stability of Oxygenation
Conditions: Respiratory Distress Syndrome, Newborn;   Bronchopulmonary Dysplasia;   Ventilator Induced Lung Injury
Intervention: Other: HFOV combined with sigh breaths
Outcome Measures: Delta-a/A-ratio;   stability of oxygen saturation;   FiO2;   Partial pressure of CO2;   heart rate;   Partial pressure of O2
5 Recruiting The Effect of Adding Intraoperative Regional Anesthesia on Cancer Recurrence in Patients Undergoing Lung Cancer Resection
Condition: Lung Cancer
Interventions: Other: General-epidural anesthesia and analgesia;   Other: Balanced general anesthesia and postoperative opioids
Outcome Measures: disease-free survival;   NK cell function;   Immune function markers;   Pain
6 Recruiting CO2 Monitoring Study
Conditions: Chronic Pain;   Hypercapnia;   Quality of Life
Intervention:
Outcome Measures: Number of events of respiratory depression and/or respiratory Depression;   Quantity and quality of pain;   Work quality For Nursing staff;   Amount of delivered/demanded doses of consumed opioids;   Incidence of adverse effects
7 Unknown  Application of CO2 Insufflations in Colonoscopy Randomized Trial
Conditions: Colorectal Neoplasm;   Colorectal Cancer
Intervention: Other: CO2 insufflations
Outcome Measures: Degree of abdominal discomfort during and after colonoscopy;   Number of neoplasm detected
8 Recruiting Go Girls! Fitness Support Group Intervention Effectiveness Study
Conditions: Polycystic Ovary Syndrome;   Abnormal Weight Gain;   Excess Weight;   Insulin Resistance;   Premature Adrenarche;   Type 2 Diabetes Mellitus
Intervention: Behavioral: Go Girls! Fitness Support Group
Outcome Measures: Increase in mean score for the PACES scale after 6-months of intervention;   Increase in mean score for the PACES scale after 3-months of intervention;   Increased amounts of average daily moderate-vigorous exercise;   Increased amounts of average daily vigorous exercise;   More positive attitudes about exercise;   Improved anthropometric and biochemical indices of metabolism and possible PCOS
9 Unknown  Evaluation of Endocrine and Metabolic Parameters in the New Diagnostic Phenotypes of Polycystic Ovary Syndrome
Condition: Polycystic Ovary Syndrome
Intervention: Procedure: Blood samples, transvaginal ultrasound
Outcome Measure: Serum levels: Total, bioavailable testosterone, Free androgen index. Total, LDL and HDL Cholesterol, Triglycerides, insulinemia, OGTT, HOMA index, Adiponectin, C Reactive Protein. Transvaginal Ultrasound:Number,size of ovary follicles and ovary volume
10 Unknown  Metformin and Oral Contraceptives in PCOS
Condition: Polycystic Ovary Syndrome
Interventions: Drug: Metformin;   Drug: Yasmin
Outcome Measures: Changes in fasting insulin and area under the curve for insulin (2 hours);   Changes in BMI, WHR, LH, FSH, total and free testosterone, fasting blood glucose, fasting C-peptide, urine-cortisol secretion, body composition, number of hypoglycaemic cases, AUC for insulin, glucose and C-peptide during OGTT (2 and 5 ho
11 Recruiting Comparison Between FSH and Letrozole in Women With Clomiphene Resistant Polycystic Ovarian Syndrome
Condition: Infertility
Interventions: Drug: FSH;   Drug: Letrozole
Outcome Measures: Ovulation;   Pregnancy
12 Unknown  Reflexology's Effect on Polycystic Ovary Syndrome (PCOS)
Condition: Polycystic Ovary Syndrome
Intervention: Other: Reflexology
Outcome Measures: To identify the most appropriate primary outcome measure for the ensuing RCT;   Attainment of normal menstrual cycle length (i.e. 21-35 days);   Hormonal imbalances and irregular menses (commonly regarded at 6 cycles per annum or less);   Weight, body mass index (BMI), hirsutism, thinning hair;   Fasting Insulin and blood sugar levels;   Quality of Life
13 Recruiting Comparison Between Combined Purified Urinary FSH and Metformin Versus Ovarian Drilling in Women With Clomiphene Resistant Polycystic Ovarian Syndrome: A Randomised Controlled Trial
Condition: Infertility
Interventions: Drug: FSH;   Procedure: Laparoscopic ovarian drilling
Outcome Measures: Ovulation;   Proportion of women getting pregnant
14 Not yet recruiting Dopamine D-2 Antagonist Use in Poor Responders in IVF: a Randomized Controlled Trial
Conditions: in Vitro Fertilization;   Dopaminergic Drugs;   Ovarian Follicles
Intervention: Drug: metoclopramide
Outcome Measures: Number of oocytes retrieved;   Number of mature follicles (≥1.5cm) seen on transvaginal ultrasound at the time of ovulation trigger;   Peak serum estradiol levels measured at the time of ovulation trigger shot;   Ratio of mature/ immature oocytes obtained at oocyte retrieval;   Follicular fluid levels of VEGF, VEGFR-1 and VEGFR-2;   Total dose of gonadotropins used and number of days of stimulation;   Fertilization rates;   Number of embryos on day 3 and 5;   Pregnancy and implantation rates;   Serum prolactin levels on cycle day 3,7 and at the time of ovulation trigger
15 Recruiting Saxagliptin + Metformin Compared to Saxagliptin or Metformin Monotherapy in PCOS Women With Impaired Glucose Homeostasis
Conditions: Polycystic Ovary Syndrome;   Disorder of Glucose Regulation
Interventions: Drug: Metformin XR;   Drug: Saxagliptin;   Drug: Saxagliptin-Metformin XR
Outcome Measures: Fasting and 2 hour glucose levels after glucose load;   ß-cell compensatory function;   Surrogate measures of insulin sensitivity and secretion;   Cardiometabolic risk factors;   Free androgen index
16 Recruiting Evaluation of Oral Lipid Ingestion in Relation to Ovarian Androgen Secretion in Polycystic Ovary Syndrome (PCOS)
Condition: Polycystic Ovary Syndrome
Intervention: Drug: Salsalate
Outcome Measures: White blood cell nuclear factor kappa B (NFkappaB) activation in response to oral lipid ingestion and ovarian androgen secretion in response to human chorionic gonadotropin (HCG) stimulation.;   White blood cell NFkappaB activation following oral lipid ingestion in response to 12 weeks of salsalate or PCE administration.;   Ovarian androgen secretion following HCG administration in response to 12 weeks of salsalate or PCE administration.;   Body composition status measured by DEXA in response to 12 weeks of salsalate or PCE administration.;   Insulin sensitivity derived from an OGTT in response to 12 weeks of salsalate or PCE administration.;   Ovulation rates documented by serum progesterone in response to 12 weeks of salsalate or PCE administration
17 Unknown  Development of a Structured Education Programme for Women With Polycystic Ovary Syndrome
Condition: Polycystic Ovary Syndrome
Intervention: Behavioral: Structured Lifestyle Education
Outcome Measures: we aim for a 2000 steps increase in Number of steps per day;   Physical Activity;   Biochemical variables;   Anthropometric and demographic;   Health Related Quality of Life;   Exercise and Barrier Self Efficacy;   Epworth Sleepiness Scale;   Body Fat Composition;   Brief Illness Perception
18 Unknown  Reflexology's Effect on Polycystic Ovary Syndrome: A Pilot Study
Condition: Polycystic Ovary Syndrome
Intervention: Other: Reflexology
Outcome Measures: To identify the most appropriate primary outcome measure for the ensuing RCT;   Attainment of normal menstrual cycle length (i.e. 21-35 days);   Hormonal imbalances and irregular menses (commonly regarded at 6 cycles per annum or less);   weight, body mass index (BMI), hirsutism, thinning hair;   Fasting Insulin and blood sugar levels;   Quality of Life
19 Recruiting Letrozole Versus Chinese Herbal Medicine on Polycystic Ovary Syndrome (PCOS)
Condition: Polycystic Ovary Syndrome
Interventions: Drug: Letrozole;   Drug: Chinese herbal medicine granules or Chinese herbal medicine granules placebo
Outcome Measures: Live birth rate;   Ovulation rate;   Miscarriage rate;   Change in hormonal profile;   Change in metabolic profile;   Change in physical measurements;   Pregnancy complications;   Birth defects;   Safety parameters;   Side effect profile
20 Recruiting IR, Inflammatory and Cardiovascular Markers in PCOS Among Obese and Non-obese Women
Conditions: Polycystic Ovary Syndrome,;   Insulin Resistance,
Intervention:
Outcome Measure: Studying the insulin resistance, inflammatory and cardiovascular markers in polycystic ovary syndrome among obese and non-obese women.

These studies may lead to new treatments and are adding insight into Pco2 Increased etiology and treatment.

A major focus of Pco2 Increased research is the development of new drugs and other treatment options. Studies seek to identify new drugs to treat various related disorders and to find safer, more effective doses for medications already being used. Other research is aimed at identifying receptors or drug targets.


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