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Pharyngeal Injury Medical Research Studies

Up-to-date List of Pharyngeal Injury Medical Research Studies

What Research is Being Done?

A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two main types of clinical studies: clinical trials (also called interventional studies) and observational studies. Following list includes both interventional and observational studies.

Latest Pharyngeal Injury Medical Research Studies

Rank Status Study
1 Recruiting Impact of Blades Used for Scheduled Orotracheal Intubation on Postoperative Sore Throat
Conditions: Tracheal Intubation Morbidity;   Sore Throat
Interventions: Device: metal reusable blades MacIntosh;   Device: Single use plastic blades HEINE XP®
Outcome Measures: The frequency of patients presenting a post-operative sore throat whose intensity is above 4 on a visual analogue scale (VAS) graded from 0 (no pain) to 10 (unbearable pain) collected at the discharge of the post-anesthesia care unit (PACU).;   The frequency of patients presenting a post-operative sore throat whose intensity is different from 0/10 without swallowing;   The pain intensity will be measured at the discharge of the post-anesthesia care unit (PACU) with a slide ruler displaying a visual analogue scale graded from 0 (no pain) to 10 (unbearable pain) on the blinded face;   the degree of voice modification on a VAS;   the sore throat VAS during swallowing.;   jaw pain;   lips injuries;   dental injuries;   blood on the blade;   the intubation difficulty score (IDS);   the frequency of difficult intubation;   the frequency of change of blade during the tracheal intubation procedure;   the tracheal intubation duration.
2 Not yet recruiting Do Pharyngeal Packs During Orthognathic Surgery Reduce Postoperative Nausea and Vomiting
Conditions: Nausea;   Vomiting
Intervention: Device: pharyngeal pack
Outcome Measures: the incidence and severity of any nausea, emetic episodes (retching or vomiting), or both (i.e., postoperative nausea and vomiting) during the first 24 postoperative hours.;   The incidence and severity of throat pain;   the incidence of oral mucosal injury;   satisfactory scores of patients
3 Recruiting Study of Ganciclovir/Valganciclovir for Prevention of Cytomegalovirus Reactivation in Acute Injury of the Lung and Respiratory Failure
Conditions: Acute Lung Injury;   Acute Respiratory Distress Syndrome;   Respiratory Failure
Interventions: Drug: IV Ganciclovir;   Drug: Placebo
Outcome Measures: Serum IL-6 level;   Incidence of CMV reactivation at 28 days (blood, throat);   Additional cytokine levels;   Clinical outcomes;   Length of stay;   CMV disease;   Safety;   Functional assessment
4 Not yet recruiting Laryngeal Mask Airway Removal During Deep Anesthesia in Children
Condition: Post Operative Sore Throat After LMA Removal
Intervention: Other: LMA removal
Outcome Measures: Incidence of Postoperative Sorethroat;   Dysphagia;   Dysphonia;   Adverse event: teeth or mucosal trauma;   laryngospasm;   Bronchospasm;   Desaturation;   Nausea and vomiting;   cough
5 Unknown  Comparison Study of Two Supraglottic Devices Used for Patients Under General Anesthesia
Condition: Patent Airway
Intervention: Device: Supraglottic airway device insertion
Outcome Measures: Measure of the airway leak pressure;   Measure of the peak airway pressure;   Time needed to secure the airway;   Number of attempts to introduce the devices;   Adverse effects after anesthesia (cough, sore throat, dysphagia, trauma, dysphonia);   Airway manipulation
6 Unknown  Voice Prosthesis Made in Porous Titanium After Total Laryngectomy or Pharyngolaryngectomy
Conditions: Pharyngeal Neoplasms;   Laryngeal Neoplasms;   Carcinoma
Interventions: Device: prothesis voice;   Procedure: total laryngectomy
Outcome Measures: Clinical measures concerning peri and intra prosthetic leakage;   Phonology's measures
7 Recruiting Dexamethasone and Wound Healing After Thyroid Surgery
Condition: Wound Infection
Interventions: Drug: Dexamethasone;   Drug: saline
Outcome Measures: the total wound drain after the operation, including the drain in bulb and stain area in dressings,;   patient pain scores, including incision pain and throat pain,;   c-reaction protein levels in drainage fluid and blood during perioperative period.
8 Unknown  The Effects of Bimanual Laryngoscopy on Post-Operative Sore Throat in Adults
Conditions: Postoperative Sorethroat;   Bimanual Laryngoscopy
Intervention:
Outcome Measure:
9 Recruiting Blind Intubation Through The Self-Pressurised Disposable Air-Q Laryngeal Intubation Mask: An International Multicentre Trial
Condition: Elective Surgery Requiring Tracheal Intubation Using an Oral Tracheal Tube
Intervention: Device: Air-Q Intubation Laryngeal Mask
Outcome Measures: Success rate of blind intubation via the disposable Air-Q self-inflating laryngeal intubation mask.;   Time for insertion of the Air-Q laryngeal mask;   Time for insertion of the tube;   First attempt rate and second attempt rate;   Time for removal of the Air-Q ILA device after successful intubation;   Rate of misplacement of the ILA;   Rate of misplacement of the tube;   risk factors of insertion failures;   Rate of airway injuries;   Tightness during leak test before relaxation;   Tightness during leak test after relaxation;   Maximum drop of saturation during airway management;   Rate of adverse events;   Rate of necessity of alternative airway device;   Rate of blood stained devices after removal of the ILA;   Postoperative coughing after 2 hours and the next morning;   Postoperative hoarseness after 2 hours and the next morning
10 Unknown  Using Lignocaine Spray and Gel to Reduce the Pain Associated With Nasogastric Tube Insertion in Children
Condition: Intubation; Difficult
Interventions: Drug: Lignocaine;   Drug: Placebo
Outcome Measure: Reduction in mean visual analogue scores (VAS) in study arm
11 Recruiting The Influence of Degree of Head Elevation on Insertion Success for ProSeal Laryngeal Mask Airway Insertion
Condition: Anesthesia
Intervention: Device: Insertion of ProSeal laryngeal mask airway
Outcome Measures: insertion success rate;   complication
12 Unknown  GlideScope Groove vs. Standard GlideScope: A Non-inferiority Study
Condition: Intubation, Orotracheal
Interventions: Device: GlideScope Groove;   Device: Control: Standard GlideScope
Outcome Measures: Duration of Intubation;   Ease of intubation;   Incidence of trauma;   Number of failures to intubate;   Use of external laryngeal pressure;   Laryngoscopic grade distribution;   Sore Throat
13 Recruiting Time to Intubation (TTI) of Obese Patients. A Comparison Macintosh Laryngoscope and Stortz Video Laryngoscope
Condition: Obese
Interventions: Device: Conventional Macintosh laryngoscope;   Device: Stortz videolaryngoscope
Outcome Measures: Time to intubation seconds (s);   Presence and level of postoperational throat pain;   Ease of intubation;   Incidence of trauma in each group;   Number of attempts of intubation
14 Recruiting Establish Quantitative Measurements of Laryngeal Sensorimotor Functions and Evaluating the Grade of Phonation and Swallowing Impairment
Condition: Unilateral Vocal Cord Paralysis
Intervention:
Outcome Measures: Fiberoptic endoscopic evaluation of swallowing (FEES);   Laryngo-pharyngeal mucosa sensation test;   laryngeal electromyography;   laboratory voice analysis;   voice range profile;   Voice Handicap Index (VHI);   Disease related life quality assessment: FACT-H&N, FACT-E
15 Recruiting Effects of Shoulder Edema on Intubated Tube in Patients Undergoing Shoulder Arthroscopy
Condition: Arthroscopy
Intervention:
Outcome Measure: Direct intracuff pressure measurement technique using manometer
16 Unknown  Evaluation of Oral Needs of Children With Disorder Attention Deficit/Hyperactivity Disorder
Condition: Attention Deficit Disorder With Hyperactivity
Intervention:
Outcome Measures: Cod and CAOD index for caries,PI and GI indices for periodontal disease, dysfunction and malocclusion classification by WHO and Analysis cephalometric;   Measurement of anxiety through the CFSS-DS scale (Dental subscale of Children's Fear Survey Schedule, Schedule 1)
17 Unknown  Improving Oral Care to Reduce Hospital-Acquired Pneumonia (HAP) in the Acute Neurologically Impaired Adult
Condition: Pneumonia
Intervention: Other: Enhanced oral care protocol
Outcome Measure: Hospital Acquired Pneumonia Occurrences
18 Recruiting King Vision and Cervical Spines Movement
Condition: Need Tracheal Intubation
Interventions: Device: Macintosh-King Vision;   Device: King Vision-Macintosh
Outcome Measures: cervical spine movement;   time to intubation;   laryngoscopic view;   ease of intubation;   number of intubation attempts;   number of optimization maneuvers
19 Unknown  Efficacy Study of Botulinum Toxin (BOTOX) Injections to Treat Vocal Fold Granulomas
Conditions: Contact Ulcer of Vocal Folds;   Granuloma of Vocal Cords;   Granuloma, Laryngeal;   Granuloma
Interventions: Drug: onabotulinumtoxinA;   Drug: omeprazole (proton pump inhibitor)
Outcome Measures: Complete resolution of vocal fold granuloma;   Voice Handicap Index score
20 Unknown  Comparison of Two Insertion Techniques of Proseal Laryngeal Mask Airway by Unskilled Personnel in Children
Condition: Airway Management
Intervention: Procedure: McIvor retractor
Outcome Measures: the success rate of proseal laryngeal mask airway (PLMA) insertion;   the incidence of complications following PLMA insertion

These studies may lead to new treatments and are adding insight into Pharyngeal Injury etiology and treatment.

A major focus of Pharyngeal Injury research is the development of new drugs and other treatment options. Studies seek to identify new drugs to treat various related disorders and to find safer, more effective doses for medications already being used. Other research is aimed at identifying receptors or drug targets.


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