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Phenelzine Medical Research Studies

Up-to-date List of Phenelzine Medical Research Studies

What Research is Being Done?

A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two main types of clinical studies: clinical trials (also called interventional studies) and observational studies. Following list includes both interventional and observational studies.

Latest Phenelzine Medical Research Studies

Rank Status Study
1 Recruiting Phenelzine Sulfate and Docetaxel in Treating Patients With Prostate Cancer With Progressive Disease After First-Line Therapy With Docetaxel
Conditions: Adenocarcinoma of the Prostate;   Hormone-resistant Prostate Cancer;   Recurrent Prostate Cancer
Interventions: Drug: docetaxel;   Procedure: prostate biopsy;   Other: laboratory biomarker analysis;   Drug: Phenelzine sulfate
Outcome Measures: Proportion of patients who experience a PSA decline of at least 30%;   Duration of progression free survival after initiation of combination Phenelzine and docetaxel therapy;   Response rate in measurable disease by RECIST criteria;   Maximum change in PSA;   Toxicity of the regimen;   Time to death from all causes;   Frequency of MAOA overexpression in CRPC tumors that are progressing on docetaxel;   HIF-1alpha expression in circulating tumor cells as a potential measure of MAO and activity;   MAOA expression in circulating tumor cells and comparison to biopsy MAOA expression
2 Recruiting Detecting Central and Peripheral Biomarkers in MDD
Condition: Major Depressive Disorder
Intervention: Other: Phenelzine treatment
Outcome Measure: MAO-B VT levels measured with PET in MDE secondary to MDD
3 Not yet recruiting Supplemental Transcranial Magnetic Stimulation (TMS) vs. Standard Medication Monotherapy for Treating Major Depression: An Exploratory Field Study
Condition: 1. Major Depressive Disorder.
Interventions: Device: Supplemental TMS;   Drug: Standard Medication Monotherapy
Outcome Measures: Montgomery-Åsberg Depression Rating Scale (MADRS);   Hamilton Rating Scale for Depression (HRSD)

These studies may lead to new treatments and are adding insight into Phenelzine etiology and treatment.

A major focus of Phenelzine research is the development of new drugs and other treatment options. Studies seek to identify new drugs to treat various related disorders and to find safer, more effective doses for medications already being used. Other research is aimed at identifying receptors or drug targets.


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