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Phosphalugel Medical Research Studies

Up-to-date List of Phosphalugel Medical Research Studies

What Research is Being Done?

A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two main types of clinical studies: clinical trials (also called interventional studies) and observational studies. Following list includes both interventional and observational studies.

Latest Phosphalugel Medical Research Studies

Rank Status Study
1 Recruiting Safety, Tolerability, and Immunogenicity of the Human Cytomegalovirus Vaccine (V160) in Healthy Adults (V160-001)
Condition: Cytomegalovirus Infections
Interventions: Biological: V160 Low Dose IM;   Biological: V160 Medium Dose IM;   Biological: V160 High Dose IM;   Biological: V160 Medium Dose plus Merck Aluminum Phosphate Adjuvant (MAPA) 225 µg /dose IM;   Biological: V160 High Dose plus MAPA 225 µg /dose IM;   Biological: V160 Maximum Dose IM;   Other: Placebo IM;   Biological: V160 Medium Dose ID;   Other: Placebo ID
Outcome Measures: Percentage of Participants with an Adverse Event (AE);   Percentage of Participants with an Injection-site AE;   Percentage of Participants with a Systemic AE;   Percentage of Participants with a Serious Adverse Event (SAE);   Geometric Mean Titer of HCMV-specific Neutralizing Antibody;   Geometric Mean Count of Peripheral Blood Mononuclear Cells Secreting Interferon-Gamma;   Geometric Mean Concentration of Interferon-Gamma after Stimulation of Whole Blood Sample with Pooled HCMV Antigen Peptides
2 Not yet recruiting Dose-Finding Study of S.Pneumoniae Whole Cell Vaccine Adsorbed to Alum (PATH-wSP) in Healthy Kenyan Adults and Toddlers
Condition: Pneumonia, Pneumococcal
Interventions: Biological: PATH-wSP;   Biological: pneumococcal polysaccharide conjugate vaccine (adsorbed);   Biological: Diptheria Pertussis Tetanus Hep B Haemophilus b Conjugate;   Other: Saline
Outcome Measures: Proportion of subjects with reactogenicity events;   To evaluate the distribution of antibody concentrations in pre- and post-vaccination sera following each vaccination for pneumococcal-specific proteins and for neutralizing antibody responses
3 Recruiting Pneumococcal Vaccines Early and in Combination
Condition: Otitis Media
Interventions: Drug: Synflorix;   Drug: Prevenar13;   Drug: COMBO
Outcome Measures: Immunogenicity;   nasopharyngeal carriage;   otitis media

These studies may lead to new treatments and are adding insight into Phosphalugel etiology and treatment.

A major focus of Phosphalugel research is the development of new drugs and other treatment options. Studies seek to identify new drugs to treat various related disorders and to find safer, more effective doses for medications already being used. Other research is aimed at identifying receptors or drug targets.

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