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Pneumothorax Medical Research Studies

Up-to-date List of Pneumothorax Medical Research Studies

What Research is Being Done?

A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two main types of clinical studies: clinical trials (also called interventional studies) and observational studies. Following list includes both interventional and observational studies.

Latest Pneumothorax Medical Research Studies

Rank Status Study
1 Recruiting Wedge Resection or Parietal Pleurectomy for the Treatment of Recurrent Pneumothorax (WOPP)
Conditions: Pneumothorax;   Recurrent Pneumothorax
Interventions: Procedure: wedge resection;   Procedure: parietal pleurectomy
Outcome Measures: Recurrence rate of primary Pneumothorax following VAT surgery;   postoperative morbidity;   postoperative pain;   quality of life;   costs of treatment
2 Recruiting Comparison of Exsufflation Versus Drainage in Primary Spontaneous Pneumothorax
Condition: Pneumothorax
Interventions: Procedure: exsufflation;   Procedure: thoracic tube drainage
Outcome Measures: size of residual Pneumothorax measured on chest radiography;   size of residual Pneumothorax at one week;   recidive of Pneumothorax at one year
3 Unknown  A Prospective Randomised Study of Efficacy, Safety and Costs of Talc Pleurodesis Under Medical Thoracoscopy and Pleurodesis Under Video-assisted Thoracoscopy Surgery for Recurrent Primary Spontaneous Pneumothorax
Condition: Pneumothorax
Interventions: Other: talc pleurodesis under medical thoracoscopy;   Other: pleurodesis under video-assisted thoracoscopy surgery
Outcome Measure: to show the non-inferiority of talc pleurodesis under medical thoracoscopy versus pleurodesis under video-assisted thoracoscopy surgery for recurrent primary spontaneous Pneumothorax
4 Recruiting Intrapleural Minocycline After Simple Aspiration for the Prevention of Primary Spontaneous Pneumothorax
Condition: Pneumothorax
Interventions: Procedure: Simple aspiration with minocycline pleurodesis;   Procedure: simple aspiration
Outcome Measures: to compare the rates of ipsilateral recurrence between the minocycline and observation groups after simple aspiration of the Pneumothorax.;   Safety profile of minocycline pleurodesis;   Early results, including immediate success rates, one-week success rates, complication rates, rates of hospitalization, duration of hospitalization, and the degrees of chest pain.;   Long-term effects of minocycline pleurodesis, including degrees of residual chest pain and pulmonary function test
5 Unknown  Pathogenesis of Primary Spontaneous Pneumothorax
Condition: Pneumothorax
Intervention: Procedure: Thoracoscopic bullectomy
Outcome Measure:
6 Recruiting Absorbable Mesh Pleurodesis in Thoracoscopic Treatment of Spontaneous Pneumothorax
Conditions: Spontaneous Pneumothorax;   Surgery
Interventions: Procedure: Thoracoscopic bullectomy and pleural abrasion;   Biological: Mesh coverage of the staple line
Outcome Measures: the rates of ipsilateral Pneumothorax recurrence;   Safety of mesh coverage;   long-term safety of mesh coverage
7 Unknown  Pleural Abrasion Plus Minocycline Versus Apical Pleurectomy for Primary Spontaneous Pneumothorax
Condition: Pneumothorax
Interventions: Procedure: 1 apical pleurectomy;   Procedure: 2 pleural abrasion + minocycline pleurodesis
Outcome Measures: Recurrence rate of Pneumothorax after thoracoscopic operation.;   The short-term results (Pain level, chest tube duration, hospital stay, etc);   Complication rate;   Long-term results: residual pain;   Long-term pulmonary function test
8 Unknown  Pigtail Catheter Versus Chest Tube in the Management of Traumatic Pneumothorax
Condition: Traumatic Pneumothorax
Interventions: Device: Pigtail catheter insertion (Cook);   Device: chest tube (28-French)
Outcome Measures: Change in Tube-site pain, pain medication requirement;   failure rate;   Insertion-related complication
9 Recruiting Improving Primary Spontaneous Pneumothorax (PSP) Treatment Techniques in VATS
Conditions: Pneumothorax;   Pleurodesis
Intervention: Procedure: VATS pleurodesis
Outcome Measures: Recurrence of Primary Spontaneous Pneumothorax (PSP);   Did not recurrence
10 Recruiting Chest Tube Drainage or Thoracoscopic Surgery for Failed Aspiration of Spontaneous Pneumothorax
Condition: Pneumothorax
Interventions: Procedure: Video-assisted thoracoscopic surgery;   Procedure: chest tube drainage
Outcome Measures: Comparing the number of days in hospital, after intervention, of each group.;   Short-term outcome, including number of days with chest drainage, total hospital stay, short-term failure rate of assigned treatment, adverse events, pain score, mean dose of meperidine requested.;   Long-term outcome, including recurrence rate and long-term failure rate of assigned treatment;   Total costs of each patients in assigned treatment.
11 Recruiting Management of Occult Pneumothoraces in Mechanically Ventilated Patients
Condition: Pneumothorax
Interventions: Procedure: chest drainage;   Other: close clinical observation
Outcome Measures: Outcome Variables: In ventilated patients with small to moderate sized occult PTXs, the rate of respiratory distress will not differ between those treated with chest thoracostomy tubes and those not treated but simply observed;   Observation of small OPTXs in ventilated patients will not increases the rates of Emergency chest drainage, Death, tracheostomy, ARDS, Ventilator associated pneumonia (VAP), or the Abdominal Compartment Syndrome (ACS)
12 Unknown  Additional Minocycline Pleurodesis After Thoracoscopic Procedures for Primary Spontaneous Pneumothorax
Condition: Pneumothorax
Intervention: Drug: intrapleural minocycline instillation
Outcome Measures: The primary end point was rates of ipsilateral recurrence after the operation.;   safety of minocycline;   early postoperative results of minocycline;   long-term complication of minocycline;   long-term effect on pulmonary function of minocycline pleurodesis
13 Unknown  Intrapleural Minocycline After Aspiration of Spontaneous Pneumothorax
Condition: Pneumothorax
Intervention: Procedure: Intrapleural Minocycline application
Outcome Measure: Recurrence rate
14 Recruiting Effect of Mechanical Ventilation on the Incidence of Pneumothorax After Subclavian Vein Catheterization
Condition: Subclavian Vein Catheterization
Interventions: Other: Lungs were not mechanically ventilated during subclavian vein catheterization;   Other: Lungs were mechanically ventilated during subclavian vein catheterization
Outcome Measures: incidence of Pneumothorax;   catheterization success rate
15 Unknown  No Routine CXR After Bronchoscopy
Condition: Pneumothorax
Intervention:
Outcome Measure:
16 Recruiting Study of the Disease Process of Lymphangioleiomyomatosis
Conditions: Lung Disease;   Pneumothorax;   Tuberous Sclerosis
Intervention:
Outcome Measure:
17 Not yet recruiting Digital Air Leak Monitoring for Patients Undergoing Lung Resection
Conditions: Pneumothorax;   Atelectasis
Interventions: Device: Digital pleural drainage system;   Device: Dry suction pleura drainage device
Outcome Measures: length of hospital stay;   duration of chest tube insertion
18 Unknown  Use of Orotracheal Continuous Positive Airway Pressure (CPAP) in Newborns With Respiratory Failure
Condition: Neonatal Respiratory Failure
Intervention: Device: OROTRACHEAL cpap WITH COMPENSATION BAG ( GREGORY CPAP)
Outcome Measures: mortality. Pneumothorax , oxygen at 36 weeks of gestational age;   infections rate, failure to treatment , other complications.
19 Unknown  A Comparative Study of the Safety and Efficacy of Face Talc Slurry and Iodopovidone for Pleurodesis
Conditions: Malignant Pleural Effusions;   Recurrent Pleural Effusions;   Primary Spontaneous Pneumothorax;   Secondary Spontaneous Pneumothorax
Intervention: Procedure: Pleurodesis with either talc or iodopovidone
Outcome Measures: Success;   Failure;   Death;   Pain by VAS;   Time to Pleurodesis;   Others
20 Recruiting The ISET (Isolation by Size of Epithelial Tumor Cells) and the CellSearch Methods in Malignant Pleural Mesothelioma
Conditions: Pleural Neoplasms;   Mesothelioma;   Pneumothorax;   Parathyroid Neoplasms;   Benign Tumor of the Thyroid;   Tumor of the Thyroid
Interventions: Other: Blood sampling;   Other: Control Group
Outcome Measures: Evaluation of presence / absence of CTC on the global survival;   Value forecasts of the number of CTC on the global survival estimated by the risk

These studies may lead to new treatments and are adding insight into Pneumothorax etiology and treatment.

A major focus of Pneumothorax research is the development of new drugs and other treatment options. Studies seek to identify new drugs to treat various related disorders and to find safer, more effective doses for medications already being used. Other research is aimed at identifying receptors or drug targets.


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