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Polyethyl Medical Research Studies

Up-to-date List of Polyethyl Medical Research Studies

What Research is Being Done?

A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two main types of clinical studies: clinical trials (also called interventional studies) and observational studies. Following list includes both interventional and observational studies.

Latest Polyethyl Medical Research Studies

Rank Status Study
1 Recruiting Comparison of 4L Polyethylene Glycol and 2L Polyethylene Glycol With Ascorbic Acid in Inactive UC Patients
Condition: Ulcerative Colitis
Interventions: Drug: Polyethylene glycol;   Drug: Ascorbic Acid
Outcome Measures: Number of patients who are willing to use the same preparation method for the next colonoscopy.;   Number of patients who have ulcerative colitis symptom aggravation within 30 days after bowel preparation, measured by simple clinical colitis activity index (SCCAI).
2 Not yet recruiting Colon Cleansing Quality of Polyethylene Glycol Compared With Polyethylene Glycol Plus Ascorbic Acid.
Condition: Colonoscopy Preparation
Interventions: Drug: Polyethylene glycol 4000;   Drug: Macrogol 3350 plus ascorbic acid
Outcome Measures: Colon cleansing;   Tolerance of bowel preparation;   Detection of colorectal neoplasia
3 Recruiting Efficacy of 2-Liter Mixed Preparation With Bisacodyl Plus Polyethylene Glycol and 4-Liter Polyethylene Glycol for Colon Cleansing in Patients With Prior History of Colorectal Resection
Condition: Intestinal Cancer
Interventions: Drug: Polyethylene glycol;   Drug: Bisacodyl
Outcome Measures: quality of bowel preparation rated according to a modified Ottawa bowel preparation scale;   Tolerability to the preparation (specific questionaire);   safety (adverse event rate);   Lesion detection (type and lesion detection rate/patient)
4 Recruiting Efficacy of Small Bowel Preparation in Capsule Endoscopy
Condition: Gastrointestinal Bleedings
Interventions: Drug: Standard diet;   Drug: Standard Diet + 500 ml of Polyethyleneglycol;   Drug: Standard diet + 2 liters of Polyethylene glycol the day before + 500ml of Polyethylene glycol
Outcome Measures: Compare the frequencies of the diagnoses of clinically significant lesions;   The quality of the preparation and visibility of the bowel;   The clinical tolerance;   The number of all the observed lesions;   Compare different times;   Crossing (yes or no) of ileo-cecal valve by the EVC
5 Recruiting Hepatic Encephalopathy: Lactulose or Polyethylene Glycol (H.E.L.P.)
Conditions: Hepatic Encephalopathy;   HE;   Cirrhosis;   Altered Mental Status;   AMS
Interventions: Drug: Lactulose;   Drug: Polyethylene Glycol 3350
Outcome Measures: Improvement of cognition;   Duration of hospital stay
6 Recruiting Heat Loss Prevention in Very Preterm Infants in Delivery Rooms: A Multicenter, Randomized, Controlled Trial of Polyethylene Occlusive Total Body Skin Wrapping
Conditions: Hypothermia;   Preterm Infant
Intervention: Device: Polyethylene wrap
Outcome Measures: Axillary temperature taken on admission to the NICU (immediately after total body wrap and wrap removal) and again 1 hour later;   Mortality prior to hospital discharge;   Major brain injury;   percentages of hyperthermic infants at NICU admission
7 Recruiting A Prospective Radiostereometric Analysis and Clinical Evaluation of the Zimmer® Continuum® Acetabular Cup With Vitamin E Stabilized Polyethylene
Conditions: Radiostereometric Analysis;   Vitamin E Liner;   Zimmer® Continuum® Acetabular Cup
Intervention: Radiation: RSA images
Outcome Measures: Assessing the Continuum® Cup for adequate fixation to the underlying bone as measured by migration and tilt;   Assessing the migration pattern of the Continuum® Cup;   Determining a correlation between radiolucent lines (RLLs) measured by Charnley-DeLee Zone Analyses and migration characteristics using RSA;   Determine if inducible displacement is indicative of adequate fixation;   Assess the health status and functional outcome of patients with the Continuum® Cup;   Assess the wear rate of the Vitamin E Polyethylene with a ceramic femoral head;   Determine if the wear rate of the Vitamin E liner is the same in-vivo as it is in simulation testing
8 Recruiting Polyethylene Glycol for Childhood Constipation
Condition: Constipation
Intervention: Drug: Polyethylene glycol 4000
Outcome Measures: therapeutic success (passing ≥ 3 stools per week, with no loosening of stool).;   the number of stools delivered at 6th week of intervention;   the number of incontinence episodes;   the number of painful defecation;   the number of episodes of abdominal pain;   the number of patients needed laxatives during treatment;   side effects
9 Unknown  Efficacy and Safety of Polyethylene Glycol Compared With Sodium Picosulphate for Bowel Preparation Before Colonoscopy
Condition: Bowel Preparation
Interventions: Drug: Sodium Picosulphate;   Drug: Polyethylene Glycol
Outcome Measures: Percentage of patients requiring repeat colonoscopy because of poor preparation;   Patient's satisfaction as measured by questionnaire and willingness to repeat same preparation on future examination
10 Recruiting Winged Perimeter Versus Traditional Plastic Biliary Stent for Malignant Bile Duct Obstruction
Condition: Malignant Tumor of Extrahepatic Bile Duct
Interventions: Device: WInged perimeter biliary stent insertion (Viaduct);   Device: traditional Polyethylene stent insertion (Cotton Huibregtse)
Outcome Measures: Stent patency time;   Etiology of stent failure;   Compare number of patients with device related adverse events;   Identify patient factors associated with stent failure;   Survival between the two groups
11 Recruiting Comparison of Local Made and Imported Porous Polyethylene Orbital Implant for Enucleation in Thailand
Condition: Phthisis Bulbi
Interventions: Device: 3DP;   Device: Medpor
Outcome Measures: Exposure rate;   Infection rate;   Motility;   Gadolinium enhancement
12 Recruiting Zimmer Continuum Metal on Polyethylene (MoP) PostMarket Clinical Followup (PMCF) Study
Conditions: Avascular Necrosis;   Osteoarthritis;   Inflammatory Arthritis;   Post-traumatic Arthritis
Intervention: Device: Continuum(R) Metal on Polyethylene Acetabular System
Outcome Measures: Evaluation of the Harris Hip Score - is there a change between each visit interval?;   Radiographic Evaluation- is there a change between each visit interval?
13 Unknown  Split Dose Polyethylene Glycol (PEG) + Clear Fluids Versus Split Dose PEG + Low-Residue Diet
Condition: Colorectal Cancer
Interventions: Other: Split-dose PEG Based Lavage (2L + 2L) with Low-Fibre Lunch Dietary instructions;   Other: Split-dose PEG Based Lavage (2L + 2L) with Standard Dietary Instructions
Outcome Measures: Quality of Bowel Cleanliness;   Patient satisfaction with preparation
14 Recruiting Evaluation of the Wear of Vitamin E Treated Polyethylene Components in Primary THA Using RSA
Conditions: Osteoarthritis of Hip;   Traumatic Arthritis of Hip
Intervention: Procedure: Hip replacement
Outcome Measure: Short-term femoral head penetration,long-term steady state wear of Polyethylene. Stability of acetabular & femoral components. Clinical questionnaires to assess preop,clinical outcomes,& patient satisfaction.
15 Recruiting A Study of The Effect of Altitude on Mircera (Methoxy Polyethylene Glycol-Epoetin Beta) Dose Requirements in Patients With Chronic Renal Anemia in Pre-Dialysis or Dialysis
Condition: Anemia, Kidney Disease, Chronic
Intervention: Drug: methoxy Polyethylene glycol-epoetin beta [Mircera]
Outcome Measures: Dosage required to achieve target haemoglobin concentration of 11-12 g/dL;   Change in haemoglobin concentration;   Percentage of patients achieving target haemoglobin concentration 11-12 g/dL after 3 and 6 months of treatment;   Safety: Incidence of adverse events;   Proportion of patients requiring dose adjustments;   Incidence of red blood cell transfusions
16 Recruiting Longterm-Evaluation of Vitelene® Against Standard
Conditions: Osteoarthritis, Hip;   Arthritis
Interventions: Device: Vitelene;   Device: XLPE
Outcome Measures: Analysis and measurement of oxidation index of the Polyethylene Inlay after Revision;   Manifest radiological osteolyses;   Traceable wear of Polyethylene over 0.5 mm;   Clinical Outcome
17 Recruiting Efficacy and Safety of Prepopik™ in Children for Overall Colon Cleansing in Preparation for Colonoscopy
Condition: Need for Bowel Preparation
Interventions: Drug: Prepopik™ ½ sachet (9-12 years);   Drug: Prepopik™ 1 sachet (9-12 years);   Drug: Oral Polyethylene glycol (PEG) based preparation (9-12 years);   Drug: Prepopik™ 1 sachet (13-16 years);   Drug: Oral Polyethylene glycol (PEG) based preparation (13-16 years)
Outcome Measures: Number of subjects defined by "excellent" or "good" in the Aronchick Scale;   Incidence of adverse events;   Incidence of abnormal findings in laboratory tests;   Incidence of abnormal findings in physical exams;   Number of subjects who took the assigned dose for colon cleansing;   Frequency of each category of the "Subject's Tolerability and Satisfaction Questionaire";   Pharmacokinetic (PK) assessment: Cmax (maximum concentration of drug in the blood);   PK assessment: Tmax (time when maximum concentration of drug in the blood is achieved);   PK assessment: AUC (area under the curve correlates with the total amount of drug exposure in the blood)
18 Recruiting A Multicenter Single-blind Comparison Between Standard and Individualized Approach in Bowel Preparation Before Colonoscopy
Conditions: Bowel Cleansing Process;   Colonoscopy
Interventions: Drug: Standard approach;   Drug: Individualized approach
Outcome Measures: bowel cleansing;   patient comfort level during bowel cleansing
19 Recruiting Preparation Prior to Colonoscopy in Children
Condition: Inflammatory Bowel Diseases
Interventions: Drug: Polyethylene glycol;   Drug: picosulphate
Outcome Measures: Clean colon/Ottowa scale;   Patient reported outcome measures
20 Recruiting Patient Tolerability and Efficacy of Bowel Preparation With Split Dose Picosalax vs. Split Dose PEG
Condition: Bowel Preparation
Interventions: Drug: Polyethylene Glycol;   Drug: Picosalax
Outcome Measures: Patient tolerability;   Quality of bowel preparation

These studies may lead to new treatments and are adding insight into Polyethyl etiology and treatment.

A major focus of Polyethyl research is the development of new drugs and other treatment options. Studies seek to identify new drugs to treat various related disorders and to find safer, more effective doses for medications already being used. Other research is aimed at identifying receptors or drug targets.

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