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Pregnancy Medical Research Studies

Up-to-date List of Pregnancy Medical Research Studies

What Research is Being Done?

A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two main types of clinical studies: clinical trials (also called interventional studies) and observational studies. Following list includes both interventional and observational studies.

Latest Pregnancy Medical Research Studies

Rank Status Study
1 Recruiting Sleep Quality in PREGNANCY and Its Impact on PREGNANCY Outcomes
Conditions: Obstructive Sleep Apnea;   PREGNANCY Induced Hypertension;   High-Risk PREGNANCY;   Restless Leg Syndrome;   Infant, Very Low Birth Weight
Intervention: Other: Polysomnography and ambulatory blood pressure recording
Outcome Measures: Sleep quality in PREGNANCY and its association with PREGNANCY outcomes;   Number of patients who develop PIH and gestational diabetes
2 Recruiting Treatment of Caesarean Scar PREGNANCY
Condition: Caesarean Scar PREGNANCY
Intervention: Procedure: transvaginal resection of PREGNANCY tissue
Outcome Measures: The safety of transvaginal resection of PREGNANCY tissue in the treatment of CSP.;   the effectiveness of transvaginal resection of PREGNANCY tissue in the treatment of CSP.;   Baseline clinical characteristic of patient when diagnosed with CSP;   three year recurrence rate
3 Recruiting The Cymbalta PREGNANCY Registry
Condition: PREGNANCY
Intervention: Drug: duloxetine
Outcome Measures: To estimate the risk of major congenital anomalies among pregnancies exposed to Cymbalta;   To estimate risk of recognized spontaneous abortions, stillbirths, elective terminations, minor congenital anomalies, and any serious adverse PREGNANCY outcomes among pregnancies exposed to Cymbalta and their live births during the first year of life;   To examine any potential impact of Cymbalta use while breastfeeding on the infant during the first year of life;   To compare the risk of major congenital anomalies among pregnancies exposed to Cymbalta to an appropriate comparator(s) such as the Centers for Disease Control and Prevention (CDC) Metropolitan Atlanta Congenital Defects Program (MACDP)
4 Recruiting PREGNANCY Complications in Women With BMI>25 kg/m2 Enrolled in a Healthy Lifestyle and Eating Habits Program
Conditions: Maternal Obesity Complicating PREGNANCY, Birth,or Puerperium;   Gestational Diabetes Mellitus in PREGNANCY, Diet- Controlled;   Exercise Addiction;   High-Risk PREGNANCY;   Dietary Modification
Interventions: Behavioral: Specific Therapeutic Lifestyle Changes program in PREGNANCY;   Behavioral: Dietary and behavioral counselling in PREGNANCY
Outcome Measures: bioimpedance analyzer;   75-g 2-h Oral Glucose Tolerance Test (OGTT);   Blood Pressure assessment;   SenseWear system armband;   Pedometer (Omron Walking Style III HJ-203-EK)
5 Recruiting Personalized Management of Body Weight During PREGNANCY
Condition: Weight Gain During PREGNANCY
Intervention: Behavioral: SmartMoms
Outcome Measures: Proportion of pregnant women who gain more weight during PREGNANCY than is recommended by the Institute of Medicine;   Relationship between weight gain during PREGNANCY, the mother's physical activity and diet on the chance of the mother getting diabetes during PREGNANCY;   Relationship between weight gain during PREGNANCY, the mother's physical activity and diet on the baby's weight at birth;   Relationship between weight gain during PREGNANCY, the mother's physical activity and diet on the mother and baby's body fatness;   Relationship between weight gain during PREGNANCY, the mother's physical activity and diet on how much PREGNANCY weight the mother keeps after she delivers her baby;   Relationship between weight gain during PREGNANCY, the mother's physical activity and diet on how much the baby eats
6 Recruiting PREGNANCY Specific Nausea Questionnaire (PUQE) Translated and Tested in Norwegian
Condition: Hyperemesis Gravidarum
Interventions: Other: PREGNANCY Unique Questionnaire of Emesis (PUQE);   Other: 24 hours self-reported nutritional intake form
Outcome Measures: PREGNANCY Unique Questionnaire of Emesis (PUQE) score reported by hyperemesis patients versus normal pregnant women;   PREGNANCY Unique Questionnaire of Emesis (PUQE) score in relation to self reported 24 hours nutritional intake registration (estimated caloric intake)in hyperemesis patients versus normal pregnant women
7 Recruiting VIBATIV PREGNANCY Registry
Conditions: PREGNANCY;   Congenital Defects;   Infant, Low Birth Weight
Intervention: Drug: telavancin
Outcome Measures: Outcomes of PREGNANCY in women exposed to VIBATIV at any time during PREGNANCY;   Effect of fetal exposure to VIBATIV on PREGNANCY outcomes;   Fetal/neonatal outcomes;   Infant development and milestones through 12 months of age
8 Recruiting Assessment of Alterations in Immune Function During PREGNANCY and Post Parturition
Conditions: PREGNANCY;   Immune Function
Intervention:
Outcome Measures: Changes in lymphocyte and NK cell populations duringPREGNANCY compared to non-pregnant control samples;   Changes in Cytokine profiles during PREGNANCY compared to non-pregnant control samples;   Functionality of Toll-like receptors and changes in gene expression during PREGNANCY during PREGNANCY comparedto non-pregnant control samples;   Functionality of Toll-like receptors and changes in gene expression during PREGNANCY during PREGNANCY compared to non-pregnant control samples, in a subset of pregnant women;   Changes in lymphocyte and INK cell populations during PREGNANCY compared to non-pregnant control samples, in a subset of pregnant women;   Changes in Cytokine profiles during PREGNANCY compared to non pregnant control samples, in a subset of pregnant women
9 Recruiting Optimal Treatment for Women With a Persisting PREGNANCY of Unknown Location
Conditions: Persistent PREGNANCY of Unknown Location;   Ectopic PREGNANCY
Interventions: Drug: Methotrexate;   Procedure: Uterine Evacuation;   Other: Expectant Management
Outcome Measure: Uneventful clinical resolution of a PREGNANCY of Unknown Location without change from the initial management strategy
10 Recruiting BioThrax® (Anthrax) Vaccine in PREGNANCY Registry
Conditions: PREGNANCY Complications;   PREGNANCY Outcome;   Congenital Abnormalities
Intervention: Biological: Observational Intervention
Outcome Measures: PREGNANCY Outcomes;   Maternal Outcomes;   Infant Outcomes
11 Recruiting Exenatide PREGNANCY Registry - Type 2 Diabetes in PREGNANCY
Conditions: Birth Defects;   Type 2 Diabetes;   Preterm Birth
Intervention:
Outcome Measure: Primary Outcome
12 Recruiting CO-OP Trial: Community-based Outreach on Obesity in PREGNANCY
Conditions: Obesity;   PREGNANCY
Intervention: Behavioral: Dietary counseling. Maintain a food diary.
Outcome Measures: Dietary intervention to prevent excessive maternal weight gain during PREGNANCY;   Difference in complication rates between study and control group;   Differences between birth weights in the study and control groups;   Differences in leptin levels between study and control groups;   Difference in food frequency questionnaire responses between study and control groups;   Is infant birth weight correlated with total gestational weight gain?;   Difference in infant body weight between study and control groups;   Do study subjects use the food diary and bring to visits/subject compliance;   Barriers to healthful eating in study and control groups;   Differences in quality of life between study and control groups;   Differences in onset of lactation postpartum between study and control groups;   Differences in breastfeeding practices between study and control groups
13 Not yet recruiting Prospects for the Prevention of PREGNANCY-induced Hypertension and Preeclampsia Trial
Condition: PREGNANCY Induced Hypertension
Interventions: Drug: Combined aspirin and multinutrient supplement;   Other: Daily text reminder text messages
Outcome Measures: Development of PREGNANCY-induced hypertension (PIH) in PREGNANCY;   Maternal/obstetric outcomes;   Neonatal and infant outcomes;   Number of participants with (severe) adverse events as a measure of safety and tolerability
14 Recruiting An Observational Study of PREGNANCY And PREGNANCY Outcomes in Women With Breast Cancer Treated With Herceptin, Perjeta In Combination With Herceptin, or Kadcyla During PREGNANCY or Within 6 Months Prior To Conception (MotHER)
Conditions: Breast Cancer;   PREGNANCY
Intervention:
Outcome Measure:
15 Unknown  Thyroid Hormone Dose Adjustment in PREGNANCY
Conditions: PREGNANCY;   Hypothyroidism
Interventions: Drug: Anticipatory dose increase of levothyroxine;   Drug: levothyroxine
Outcome Measures: proportion of patients in each treatment arm euthyroid through gestation;   the proportion of patients in each arm who required, and the gestation week at which, levothyroxine dose adjustments (either increased or decreased) occurred to maintain a euthyroid state;   Determination of the necessary frequency of serum evaluation of TSH during the first half of gestation.
16 Recruiting The Savella PREGNANCY Registry
Condition: Fibromyalgia
Intervention:
Outcome Measures: The primary objective is to estimate the prevalence of major congenital anomalies among off-springs of women exposed to Savella during PREGNANCY.;   Estimate the prevalence of spontaneous abortions, stillbirths, induced abortions, minor congenital anomalies, and adverse PREGNANCY outcomes.
17 Recruiting Trial of Acupuncture Pelvic and Low Back Pain in PREGNANCY (Medical and Economical Assessment)
Condition: Disorder of PREGNANCY
Interventions: Other: acupuncture;   Other: usual care
Outcome Measures: Number and % of days during PREGNANCY with maximum pain ≤ 4/10.;   Mean Oswestry disability score;   Number and % of days with maximum pain ≤ 4/10.;   direct and indirect costs
18 Not yet recruiting Boostrix® PREGNANCY Registry
Condition: Pertussis
Intervention: Other: Data collection
Outcome Measure: Occurrence of any abnormal PREGNANCY outcomes in women intentionally or unintentionally vaccinated with Boostrix during PREGNANCY or within 28 days preceding conception
19 Unknown  Maternal and Perinatal Outcome in Women With History of Premature Labor in Previous PREGNANCY
Conditions: PREGNANCY;   Vulvovaginitis;   Uterine Cervicitis;   PREGNANCY Outcome
Intervention: Other: Active search of lower genital tract infections
Outcome Measure: Track pregnant women priority for the exams that allow the etiologic diagnosis of lower genital tract infections.
20 Not yet recruiting A Multi-center, Placebo-controlled Study to Evaluate NT100 in Pregnant Women With a History of Unexplained Recurrent PREGNANCY Loss (RPL)
Conditions: Recurrent PREGNANCY Loss;   Recurrent Miscarriage
Interventions: Drug: NT100;   Drug: Placebo
Outcome Measures: Clinical PREGNANCY;   Live birth;   Clinical PREGNANCY;   Spontaneous PREGNANCY loss;   Stillbirth;   Subjects with adverse events and serious adverse events;   Changes in clinical laboratory parameters following study drug exposure

These studies may lead to new treatments and are adding insight into Pregnancy etiology and treatment.

A major focus of Pregnancy research is the development of new drugs and other treatment options. Studies seek to identify new drugs to treat various related disorders and to find safer, more effective doses for medications already being used. Other research is aimed at identifying receptors or drug targets.


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