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Procaine Medical Research Studies

Up-to-date List of Procaine Medical Research Studies

What Research is Being Done?

A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two main types of clinical studies: clinical trials (also called interventional studies) and observational studies. Following list includes both interventional and observational studies.

Latest Procaine Medical Research Studies

Rank Status Study
1 Not yet recruiting Patients Response to Early Switch To Oral:Osteomyelitis Study
Condition: Osteomyelitis
Interventions: Drug: oral antibiotics;   Procedure: intravenous antibiotics
Outcome Measures: Clinical Failures;   Evaluation of adverse events related to the use of antibiotics;   Cost of care from the hospital perspective
2 Not yet recruiting Continuous Infusion of Local Anesthetic for Post-operative Pain Control in Ukraine
Condition: Pain
Intervention: Device: Wound Catheter
Outcome Measure: Pain Score with dressing changes
3 Recruiting Clinical Study to Evaluate the Effect of pH on Pain Upon Local Anesthetic Administration.
Condition: Local Anesthetics
Interventions: Drug: Lidocaine;   Drug: normal saline;   Drug: alkalinized lidocaine
Outcome Measures: pain score;   time until hypoesthesia;   time until anesthesia;   pain score upon needle stick.
4 Recruiting Observational Prospective Study on 2-chloroProcaine Hydrochloride 1% Safety in Intrathecal Anaesthesia
Condition: Neurological Complication, in Particular TNS or CES
Intervention: Drug: Spinal administration of chloroProcaine
Outcome Measure: Number of participants with AE,with particular attention to Neurological Symptoms (TNS) and Cauda Equina Syndrome(CES) after intrathecal anaesthesia with 2-chloroProcaine hydrochloride
5 Recruiting Comparision of the Use in Marcaine and ChloroProcaine in Rachianesthesia for the Surgical Correction of Inguinal Hernia.
Condition: Pain
Interventions: Drug: ChloroProcaine;   Drug: Marcaine
Outcome Measures: Acute pain;   Chronic pain
6 Unknown  Comparison of the Effects of Crystalloid Cardioplegia and HTK Solution for Postoperative Troponin-I and CK-MB Levels After Pediatric Cardiac Surgery
Condition: Myocardial Injury
Interventions: Drug: HTK solution;   Drug: crystalloid cardioplegia solution
Outcome Measures: myocardial protective effect of HTK solution;   hemodynamic and respiratory data
7 Recruiting Determination of the Minimum Local Analgesic Dose of Spinal ChloroProcaine in Labour
Condition: Pain Relief During Labour
Intervention: Drug: Spinal administration of chloroProcaine.
Outcome Measures: Intensity of sensory blockade during the next 15 minutes after the application of the CSE.;   Intensity of the motor blockade during the next 15 minutes after the application of the CSE.;   The analgesic effect on the labor pain during the next 15 minutes after the application of the CSE.;   Maternal heart rate during application of the CSE and the hour there after.;   Maternal blood pressure during application of the CSE and the hour there after.;   Maternal oxygen saturation during application of the CSE and the hour there after.;   Fetal heart rate during application of the CSE and the hour there after.
8 Recruiting Custodiol-HTK Solution as a Cardioplegic Agent
Conditions: Coronary Artery Disease;   Myocardial Ischemia;   Coronary Disease;   Heart Diseases;   Valvular Heart Disease
Interventions: Drug: Custodiol HTK;   Drug: Cold Blood Cardioplegia
Outcome Measures: Creatine phosphokinase MB isoenzyme (CK-MB)and troponin-I;   Changes in ejection fraction by TTE;   Cardiac dysrhythmias;   All cause mortality;   Time on Mechanically Assisted Ventilation;   Biochemical Markers - Creatine phosphokinase MB isoenzyme (CK-MB)and troponin;   Duration of Vasopressor / Inotropic Agent;   ICU Length of Stay;   Arterial Blood Gases;   Creatinine Levels;   Myocardial Infarction
9 Not yet recruiting Antibiotic Treatment and Intravenous Immunoglobulin Trial for PANDAS
Condition: Pandas
Interventions: Drug: Sertraline+Antibiotic (penicillin/azithromycin);   Drug: Sertraline+placebo;   Biological: IVIG
Outcome Measures: The improvement of OC/tic symptoms will be superior in patients treated with SSRI+AB and in case with IVIG, compared with those treated with SSRI+placebo, as assessed by the YBOCS/YGTSS;   The degree of treatment response is expected to correlate with the percentage reduction in antibodies titers following IVIG administration;   The degree of treatment response is also expected to correlate with decreased inflammation in specific regions of the brain, as demonstrated by macroscopic changes and microstructural alterations on MRI and serum and CSF cytokines and chemokines

These studies may lead to new treatments and are adding insight into Procaine etiology and treatment.

A major focus of Procaine research is the development of new drugs and other treatment options. Studies seek to identify new drugs to treat various related disorders and to find safer, more effective doses for medications already being used. Other research is aimed at identifying receptors or drug targets.

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