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Purulence Medical Research Studies

Up-to-date List of Purulence Medical Research Studies

What Research is Being Done?

A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two main types of clinical studies: clinical trials (also called interventional studies) and observational studies. Following list includes both interventional and observational studies.

Latest Purulence Medical Research Studies

Rank Status Study
1 Unknown  CRP-guided Antibiotic Treatment in COPD Exacerbations Admitted to the Hospital
Conditions: COPD;   Exacerbation;   Bronchitis;   Sputum;   C-Reactive Protein
Intervention: Other: CRP-guided antibiotic treatment
Outcome Measures: Number of patients treated with antibiotics during hospital stay;   Time to treatment failure within 30-days;   Length of stay;   Time to next exacerbation;   Symptom scores (VAS-LRTI, George's Respiratory Questionnaire);   Adverse events
2 Recruiting Bacteriology and Inflammation in Bronchiectasis
Condition: Bronchiectasis
Interventions: Drug: Fluroquinolones;   Drug: Beta-lactamase inhibitor
Outcome Measures: Sputum microbiology;   Sputum sol phase inflammatory indices;   24-hour sputum volume;   Spirometry;   Sputum Purulence;   Sputum viscosity;   SGRQ total score and the score of each domain;   Time to recovery of respective symptom;   Sputum bacterial clearance rate
3 Recruiting Comparison Between Levofloxacin and Prulifloxacin, in Internal Medicine Patients With Acute Exacerbation of COPD
Condition: COPD Exacerbation
Interventions: Drug: Levofloxacin 1 tablet 500 mg once a day;   Drug: Prulifloxacin 1 tablet 600 mg once a day
Outcome Measures: The primary objective of the study is to determine the percentage of patients with "therapeutic success" at the end of the cycle of antibiotic therapy (10 days), in the two treatment groups (levofloxacin and prulifloxacin).;   Percentage of successful treatment to day 7 of treatment
4 Recruiting Physiotherapy in Exacerbation Chronic Obstructive Pulmonary Disease
Condition: Chronic Obstructive Pulmonary Disease.
Interventions: Other: Physiotherapy program+medical treatment;   Other: Medical treatment
Outcome Measures: Strength in upper and lower limbs;   Changes in quality of life;   Respiratory parameters;   Activity monitoring;   Performance of Physical activity;   Changes in quality of sleep;   Changes in anxiety and depression
5 Recruiting Utility of Antibiotic Treatment in Non-purulent Exacerbations of Chronic Obstructive Pulmonary Disease: a Double Blinded, Randomized, Placebo-controlled Trial of Security and Efficacy
Condition: Chronic Obstructive Pulmonary Disease
Intervention: Drug: Moxifloxacin
Outcome Measures: Efficacy of treatment WITHOUT antibiotics in non-purulent exacerbations of COPD;   Efficacy/Safety in treatment on re-hospitalizations at six months.;   In-hospital stay (days);   All cause mortality;   Quality of Life (QoL) measured by the Saint George Respiratory Questionnaire
6 Recruiting The Role of Viral Infection in Acute Exacerbations of Non-cystic Fibrosis Bronchiectasis in Adults
Condition: Bronchiectasis
Intervention:
Outcome Measures: The prevalence of respiratory virus infection in adults with bronchiectasis during a pulmonary exacerbation and when clinically stable.;   The effect of respiratory virus infection on systemic and pulmonary inflammatory markers.;   The effect of respiratory virus on lung function;   The effect of respiratory virus infection on the bacterial load in bronchiectasis.;   Time to recovery of respective symptom;   The effect of respiratory virus on quality of life in patients with bronchiectasis;   To investigate if upper respiratory tract symptoms are associated with viral infections.

These studies may lead to new treatments and are adding insight into Purulence etiology and treatment.

A major focus of Purulence research is the development of new drugs and other treatment options. Studies seek to identify new drugs to treat various related disorders and to find safer, more effective doses for medications already being used. Other research is aimed at identifying receptors or drug targets.


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