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Ranibizumab) Pwdr Medical Research Studies

Up-to-date List of Ranibizumab) Pwdr Medical Research Studies

What Research is Being Done?

A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two main types of clinical studies: clinical trials (also called interventional studies) and observational studies. Following list includes both interventional and observational studies.

Latest Ranibizumab) Pwdr Medical Research Studies

Rank Status Study
1 Unknown  A Randomised Study to Assess Betadine in the Groin Wound of Patients Undergoing Primary Varicose Vein Surgery
Conditions: Varicose Veins;   Wound Infection;   Recurrence
Intervention: Drug: Betadine
Outcome Measures: groin wound infection;   - groin recurrence of varicose veins
2 Not yet recruiting Incisional Negative Pressure Dressing on Clean Closed Groin Incisions
Condition: Complication of Surgical Procedure
Interventions: Device: Incisional Neg Pressure Wound Therapy (Prevena™);   Other: Standard of Care wound therapy
Outcome Measures: Deep wound infection;   Superficial Wound Infection;   Wound dehiscence
3 Not yet recruiting PICO Above Incisions After Vascular Surgery
Condition: Wound Infection
Intervention: Device: Negative pressure wound therapy with PICO (Smith & Nephew)
Outcome Measures: Wound infection;   Costs
4 Recruiting Negative Pressure Wound Therapy for the Prevention of Surgical Site Infection Following Lower Limb Revascularization
Conditions: Surgical Wound Infection;   Peripheral Vascular Diseases
Interventions: Device: Prevena (Negative Pressure Wound Therapy Device);   Device: Standard Tegaderm (3M Healthcare, St. Paul, MN) adhesive dressing
Outcome Measures: Surgical Site Infection;   Length of stay;   Emergency room visits;   All-cause mortality;   Re-operation rate;   Amputation
5 Not yet recruiting Reducing Mesh Infections in Open Hernia Repairs
Conditions: Patients Undergoing Open Hernia Repair;   Patients Undergoing Ventral or Inguinal Hernia Repair
Interventions: Procedure: vancomycin-soaked mesh;   Procedure: plain mesh
Outcome Measures: mesh infections;   hernia recurrence;   postoperative seroma formation
6 Recruiting Vascular Surgical Antibiotic Prophylaxis Study (VSAPS 2)
Condition: MRSA - Methicillin Resistant Staphylococcus Aureus Infection
Intervention: Drug: Antibiotic Prophylaxis
Outcome Measures: Difference between number of patients with MRSA infection between two groups;   Difference between number of patients with post-op complications between two groups
7 Recruiting A Prospective Study Comparing Telescopic vs. Balloon Dissection in Single Incision Laparoscopic Inguinal Herniorraphy (SILTELESCOPIC)
Condition: Inguinal Hernia
Intervention:
Outcome Measures: Post-op pain;   • Conversion to multiport or open operation;   • Length of hospital stay;   operation time;   Analgesic requirements;   return to work or normal physical activities;   Quality of life health scores;   Cosmetic scar score;   Recurrence of hernia;   post-operative complications including urinary retention, wound infection, seroma formation, chronic pain, testicular atrophy;   cost analysis of the ports used
8 Recruiting Colonization With Extended-Spectrum Beta-Lactamase (ESBL)-Producing Organisms
Conditions: Escherichia Coli Infections;   Klebsiella Pneumonia
Intervention:
Outcome Measures: Number of colonization sites;   Time until clearance of colonization
9 Recruiting Study of the Human Microbiome in Clinical Center Patients
Condition: Multidrug Resistance
Intervention:
Outcome Measures: The primary endpoint is to accumulate a sufficiently robust body of intestinal microbiome data and clinical and epidemiological metadata to characterize fully the changes in the human microbiota that occur during the course of hospitalization an...;   Detect the presence of MDROs in biological samples obtained fromparticipants;   Determine the features of microbiota that may render patients vulnerable to or protect patients from colonization with MDROs;   Determine immune and clinical correlates of MDRO colonizationand infection.
10 Unknown  Laparoscopic Inguinal Hernia Repair- Transabdominal Preperitoneal (TAPP) Versus Totally Extra Peritoneal (TEP)
Condition: Laparoscopic Inguinal Hernia Repair
Intervention: Procedure: Laparoscopic Inguinal Hernia Repair
Outcome Measures: Operating time (in minutes);   Cost of the procedure;   Conversion rate;   Recurrence of hernia;   Major complications
11 Recruiting The Efficacy of a Self-fixating Mesh in Unilateral Open Inguinal Hernia Repair
Conditions: Primary Inguinal Hernia;   Unilateral Hernia;   Open Surgery
Intervention: Device: Self-fixating Mesh
Outcome Measures: Percentage of post operative inguinal Hernia recurrence.;   Post-operative patient quality of life will be assessed using a validated questionnaire.;   Pain will be assessed by NRS (Numerical Rating Scale);   Post-operative complications will be assessed using a validated questionnaire.
12 Recruiting Use of G-CSF to Obtain Blood Cell Precursors
Conditions: Chronic Granulomatous Disease;   Healthy;   Immunologic Disease;   Leukocyte Adhesion Deficiency Syndrome;   Severe Combined Immunodeficiency
Intervention:
Outcome Measure:
13 Recruiting Trial of Laparoscopic Compared to Open Inguinal Hernia Repair in Children Younger Than 3 Years
Condition: Inguinal Hernia
Interventions: Procedure: Laparoscopic Inguinal Hernia Repair;   Procedure: Open Inguinal Hernia Repair
Outcome Measures: The primary outcome variable will be total dose of acetaminophen administered for pain management.;   Incidence of intraoperative complications: compromise of testicular vessels, perforation of abdominal viscera.
14 Recruiting Safety of Mesh Used Repairs in Emergency Abdominal Wall Hernias. Prospective Randomized Multicenter Trial
Condition: Hernia
Intervention: Procedure: inguinal hernia repair
Outcome Measure: wound infection
15 Recruiting Efficacy Study to Evaluate Antimicrobial Effectiveness of ZuraPrep™ (ZX-ZP-0055)
Condition: Surgical Site Infection
Intervention: Drug: ChloraPrep
Outcome Measure: Reduction of skin flora
16 Recruiting Persistent Methicillin Resistant Staphylococcus Aureus Eradication Protocol (PMEP)
Condition: Cystic Fibrosis
Interventions: Drug: Inhaled Vancomycin;   Drug: Placebo (Sterile Water);   Drug: Rifampin;   Drug: Trimethoprim/Sulfamethoxazole (TMP/SMX);   Drug: Doxycycline;   Drug: Mupirocin Nasal Ointment;   Drug: 4% chlorhexidine gluconate liquid skin cleanser
Outcome Measures: Percentage of patients MRSA free by induced sputum respiratory tract culture;   Change in FEV1% predicted from baseline;   Time to First CF Exacerbation;   Total Number of Pulmonary Exacerbations;   Change if FEV1% Predicted from Screening;   Change in Patient Reported Quality of Life (CFQ-R)(respiratory);   Development of Antibiotic Resistance
17 Recruiting Wound Healing of Incisional Wounds for Bilateral Hernia Repair
Condition: Wound Healing
Interventions: Drug: Dermabond;   Drug: Hydrogen Peroxide Oxygen producing gel
Outcome Measure: Wound infection, wound dehiscence, allergic reaction to gel components, width, elevation, color, marks and general appearance measured at clinic visits.
18 Recruiting Randomized Comparison of MynxGrip Vascular Closure Device and Manual Compression for Closure After Femoral Access Angiography. The Closure Devices Used in Every Day Practice Study, CLOSE-UP III Trial
Condition: Coronary Disease
Interventions: Device: MynxGrip;   Other: Manual compression
Outcome Measures: Incidence at 30 days of the composite endpoint of serious access site related major adverse vascular events (MAVE);   Time (min) to haemostasis;   Device failure;   Vasovagal reaction until 5 minutes after end of closure procedure;   Need for new onset of manual compression;   Pain and discomfort related to the closure procedure;   Time to mobilization;   In-hospital large groin haematoma;   Bleedings according to the Bleeding Academic Research Consortium (BARC) definitions;   Major bleeding and/or bleeding necessitation blood transfusion;   Pseudoaneurysm with indication for treatment;   Arteriovenous fistula;   Groin surgery and/or possible related vascular surgery;   Infection needing antibiotics;   Need for medical evaluation of possible closure procedure related symptom(s)
19 Recruiting Randomized Comparison of ExoSeal® and Angio-Seal Vascular Closure Devices: The CLOSE-UP II Trial
Condition: Coronary Disease
Interventions: Device: Exoseal closure device;   Device: Angioseal closure device
Outcome Measures: Incidence at 30 days of the composite endpoint of access site related major adverse vascular events (MAVE);   Time to haemostasis from removing the sheath (AngioSeal) or inserting the device (ExoSeal) until haemostasis;   Device failure;   Vasovagal reaction until 5 minutes after end of closure procedure;   Need for new onset of manual compression;   Pain and discomfort related to the closure procedure;   Time to mobilization;   In-hospital large groin haematoma;   Bleedings according to the BARC definitions;   Major bleeding and/or bleeding necessitating blood transfusion;   Pseudoaneurysm with indication for treatment;   Arteriovenous fistula;   Groin surgery and/or possible related vascular surgery;   Infection needing antibiotics;   Need for medical evaluation of possible closure procedure related symptom(s)
20 Unknown  Arterial Closure Device Comparison Trial II – ACDC Trial II
Condition: Arterial Hemostasis After Coronary Intervention
Intervention: Device: closure device placement
Outcome Measures: A composite of major vascular complications defined as device failure, bleeding, large hematoma, local infection etc.;   Time to hemostasis;   Lack of ambulation per protocol;   Need for additional measures to achieve hemostasis (manual pressure, femostop use, etc.);   Minor vascular complication (minor bleeding, analgesic use);   post procedural myocardial infarction;   30 day incidence of death, MI, TVR;   Patient discomfort;   Quality of life measurements at discharge and four weeks;   Nurse resource utilization at discharge

These studies may lead to new treatments and are adding insight into Ranibizumab) Pwdr etiology and treatment.

A major focus of Ranibizumab) Pwdr research is the development of new drugs and other treatment options. Studies seek to identify new drugs to treat various related disorders and to find safer, more effective doses for medications already being used. Other research is aimed at identifying receptors or drug targets.


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