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Sski Medical Research Studies

Up-to-date List of Sski Medical Research Studies

What Research is Being Done?

A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two main types of clinical studies: clinical trials (also called interventional studies) and observational studies. Following list includes both interventional and observational studies.

Latest Sski Medical Research Studies

Rank Status Study
1 Not yet recruiting Study of Thyroid Hormones in Prematures
Condition: Transient Hypothyroxinemia of Prematurity (THOP)
Interventions: Drug: thryoid hormone T4 + oral potassium iodide (KI) for 42 days;   Drug: D5W - 5% dextrose water
Outcome Measures: Compare incidence of a COMPOSITE endpoint of "cerebral palsy (CP) or a Bayley III Composite Cognitive Score < 85" at 36 months corrected postnatal age (CA).;   Compare measures of cognitive and executive function and attention.
2 Recruiting MIBG for Refractory Neuroblastoma and Pheochromocytoma
Conditions: Relapsed Neuroblastoma;   Metastatic Pheochromocytoma
Interventions: Drug: 131 I-Metaiodobenzylguanidine (131I-MIBG);   Drug: Potassium iodide solution;   Drug: G-CSF;   Procedure: hematopoietic stem cell infusion
Outcome Measures: Number of patients who receive 131 I-MIBG.;   Disease response;   Incidence of hematologic toxicities;   Incidence of hepatic toxicities;   Incidence of Thyroid Toxicity;   Improvement of pain symptoms;   Improvement of fatigue
3 Recruiting Cross-Sectional and Longitudinal Studies of "Pre-Diabetes" in the Pima Indians
Condition: Diabetes
Outcome Measure:
4 Recruiting The Food Intake Phenotype: Assessing Eating Behavior and Food Preferences as Risk Factors for Obesity
Conditions: Obesity;   Overweight;   Overnutrition
Outcome Measure: The assessment of ad libitum food intake vending machine system.
5 Unknown  Group Education to Improve the Iodine Nutrition in Pregnancy: Cluster Randomized Trial
Conditions: Dietary Modification;   Pregnancy Jail;   Iodine Deficiency Syndrome
Intervention: Other: Group Education
Outcome Measures: Iodine deficiency;   Date of birth;   Smoking;   Iodized salt consumption;   Iodine supplementation consumption;   Education Level;   Ethnicity;   Number of pregnancies finishes;   Number of premature births;   Number of abortions;   Number of live births;   Trimester of pregnancy;   Glasses of milk a day (number);   Yogurt per week (number);   Servings of cheese per week (number);   Usual preparation of vegetables;   Use of water to boil vegetables;   Vegetable consumption per week (number);   Fish consumption per week (number);   Usual preparation of fish;   Canned tuna consumption per week (number);   Canned sardines consumption per week (number);   Meat consumption per week (number);   Cold meat consumption per week (number);   Eggs consumption per week (number);   Fruit consumption per week (number);   Nuts consumption per week (number);   Potassium iodide consumption;   Iodine  deficiency
6 Recruiting Does Provision of Point of Care CD4 Technology and Early Knowledge of CD4 Levels Affect Early Initiation and Retention on Anti-retroviral Treatment (ART) in HIV Positive Pregnant Women in the Context of Option B+ for PMTCT?
Condition: HIV/AIDS
Interventions: Device: POC CD4;   Other: Programmatic Mentoring
Outcome Measures: Retention;   Time-to-initiation;   Retention at 6 months;   Retention by CD4 count;   Cost per pregnant woman retained on ART;   Initiation within 1 month
7 Recruiting Thol'Impilo: Bringing People Into Care
Condition: HIV
Interventions: Other: Point of care CD4 testing;   Behavioral: Care Facilitation;   Other: Transport support
Outcome Measures: Time to entry into HIV care;   Proportion entering care;   Mortality;   Cost per additional participant entering into care
8 Unknown  Efficacy of Micronutrient Fortified Yoghurt in School Children for Health Benefits
Conditions: Child Development;   Cognitive Development;   Morbidity;   Physical Growth
Interventions: Dietary Supplement: Fortified Yoghurt;   Dietary Supplement: Yoghurt
Outcome Measures: Morbidity;   Growth;   Development;   School performance;   Status Indicators for iron, zinc, vitamin A and iodine
9 Recruiting Testing and Linkage to HIV Care in China
Condition: HIV
Interventions: Behavioral: One4All;   Behavioral: Standard of Care
Outcome Measures: Receipt of post-test results and counseling following testing completeness;   Proportion of treatment-eligible participants with CD4 < 350
10 Recruiting Scientific Protocol for the Study of Thyroid Cancer and Other Thyroid Disease in Belarus Following the Chernobyl Accident
Conditions: Thyroid Cancer;   Thyroid Disease
Outcome Measure:
11 Recruiting Cardiovascular Inflammation Reduction Trial
Condition: Cardiovascular Disease
Interventions: Drug: Methotrexate;   Drug: Placebo
Outcome Measures: Rate of major cardiovascular events;   Rate of all-cause mortality;   Rate of the primary endpoint plus coronary revascularization;   Rate of hospitalization for congestive heart failure;   Rate of primary endpoint plus all-cause mortality plus coronary revascularization plus congestive heart failure;   Rate of new onset type 2 diabetes among those with metabolic syndrome but not diabetes at study entry
12 Recruiting Iodine I 131 Monoclonal Antibody 3F8 in Treating Patients With Central Nervous System Cancer or Leptomeningeal Cancer
Conditions: Brain and Central Nervous System Tumors;   Intraocular Melanoma;   Lung Cancer;   Melanoma (Skin);   Metastatic Cancer;   Neuroblastoma;   Ovarian Cancer;   Retinoblastoma;   Sarcoma;   Small Intestine Cancer
Interventions: Genetic: DNA analysis;   Other: immunologic technique;   Other: pharmacological study;   Radiation: iodine I 131 monoclonal antibody 3F8;   Radiation: 131I-3F8
Outcome Measures: Six-month overall survival;   response rate;   cumulative toxicities
13 Recruiting Effectiveness of Adventitial Dexamethasone in Peripheral Artery Disease
Condition: Peripheral Arterial Diseases
Intervention: Drug: Dexamethasone Sodium Phosphate Injection, USP
Outcome Measures: MALE-POD;   Duplex ultrasound index lesion binary restenosis;   Long term safety;   Duplex ultrasound index lesion flow limiting restenosis;   Change in inflammatory biomarkers;   Vascular patency;   Clinical outcome measures;   Infusion Technical Success;   Procedural Success;   Healthcare Economics
14 Recruiting Convection-Enhanced Delivery of 124I-8H9 for Patients With Non-Progressive Diffuse Pontine Gliomas Previously Treated With External Beam Radiation Therapy
Conditions: Brain Cancer;   Brain Stem Glioma
Intervention: Radiation: Radioactive iodine-labeled monoclonal antibody 8H9
Outcome Measures: maximum tolerated dose;   safety;   overall survival
15 Recruiting Longitudinal Surveillance Registry (LSR) of ACUITY Spiral
Condition: Heart Failure
Intervention: Device: ACUITY Spiral Left Ventricular Lead
Outcome Measure: Chronic lead-related complication free rate
16 Recruiting LONGEVITY Study. Evaluation of the Device and Battery Longevity of Boston Scientific Market-released ICD and CRT-D Devices
Conditions: Implantable Cardioverter Defibrillators;   CRT-D Cardiac Resynchronization Therapy Defibrillator
Outcome Measures: Determine the rate and cause of all-cause device replacements of Boston Scientific's market-released ICD and CRT-D devices at 5 years post-implantation.;   Evaluate the battery survival of Boston Scientific's market-released ICD and CRT-D devices at 5 years post-implantation.;   Determine the rate and cause of all-cause device replacement of Boston Scientific's market-released ICD and CRT-D devices 1, 2, 3 and 4 years post-implantation.;   Evaluate battery survival of Boston Scientific's market-released ICD and CRT-D devices at 1, 2, 3 and 4 years post-implantation.;   Evaluate the device survival of Boston Scientific's market released ICD and CRT-D pulse generators at 5 years post-implantation; and compare it to the survival probability presented in the Product Performance Report (PPR).;   Evaluate potential predictors of device battery longevity at 5 years post-implantation.
17 Unknown  Epidemiologic Follow Up Study of Newly Diagnosed Epilepsy Among Seniors
Condition: Epileptic Seizures
Outcome Measures: A two-year incidence rate of new-onset seizures and/or newly-diagnosed epilepsy among seniors in southeastern Arizona.;   Compare the impact of epilepsy on the different ethnic groups of seniors with epilepsy
18 Recruiting Treatment of Chronic Deep Vein Thrombosis (DVT) and Post-Thrombotic Syndrome (PTS) With the EkoSonic Endovascular System
Conditions: Deep Vein Thrombosis;   Post-thrombotic Syndrome
Intervention: Device: EkoSonic Endovascular System
Outcome Measures: Villalta score;   Quality of Life (QOL)

These studies may lead to new treatments and are adding insight into Sski etiology and treatment.

A major focus of Sski research is the development of new drugs and other treatment options. Studies seek to identify new drugs to treat various related disorders and to find safer, more effective doses for medications already being used. Other research is aimed at identifying receptors or drug targets.

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