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Strabismus Medical Research Studies

Up-to-date List of Strabismus Medical Research Studies

What Research is Being Done?

A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two main types of clinical studies: clinical trials (also called interventional studies) and observational studies. Following list includes both interventional and observational studies.

Latest Strabismus Medical Research Studies

Rank Status Study
1 Recruiting Efficacy of Single-Shot Dexmedetomidine Versus Placebo in Preventing Pediatric Emergence Delirium in Strabismus Surgery
Conditions: Strabismus;   Delirium on Emergence;   Pediatric Disorders
Interventions: Drug: Dexmedetomidine;   Other: Placebo
Outcome Measures: Efficacy of Single-Shot Dexmedetomidine versus Placebo in Preventing Pediatric Emergence Delirium in Strabismus Surgery;   Post operative interventions
2 Recruiting Bupivacaine Injection of Eye Muscles to Treat Strabismus
Conditions: Strabismus;   Esotropia;   Exotropia;   Graves Disease;   Nystagmus
Intervention: Drug: Bupivacaine
Outcome Measures: Eye alignment;   Percentage correction of the pre-treatment eye deviation
3 Unknown  Assessing the Functional and Psychosocial Impact of Strabismus in Asian Children Using the AS-20 and IXTQ Questionnaires
Condition: Strabismus
Intervention:
Outcome Measure: Quality of life in Asian children with Strabismus
4 Unknown  Does LMA Instead of ET Tube Affect Incidence of Postoperative Vomiting in Children Undergoing Strabismus Correction?
Condition: Strabismus
Intervention:
Outcome Measure:
5 Recruiting Postoperative Subtenons Anesthesia for Postoperative Pain in Pediatric Strabismus Surgery
Condition: Strabismus
Interventions: Drug: subtenons anesthetic - preservative-free bupivacaine 0.75%;   Drug: topical anesthetic - 0.5 cc of lidocaine 3.5% ophthalmic gel;   Drug: topical control - 0.5 cc of Hypromellose 0.3% gel;   Drug: subtenons control - 0.5 cc of Normal Saline
Outcome Measures: Average pain score over the first 30 post-operative minutes using the CHEOPS scale;   Peak pain score in the first 30 minutes;   Total narcotic and anti-emetic use during post-operative recovery;   Negative postoperative behavior score on the PHBQ (post hospitalization behavioral questionnaire);   Change in pain score
6 Recruiting Comparison of Propofol 1mg/kg and Propofol 0.5mg/kg for Prevention of Emergence Agitation in Children Undergoing Strabismus Surgery During Sevoflurane Anesthesia
Condition: Strabismus
Interventions: Drug: Injection of propofol 1.0mg/kg;   Drug: propofol 0.5mg/kg;   Drug: normal saline
Outcome Measures: The incidence of the emergence agitation;   the emergence time
7 Recruiting Utility of a Survey Instrument to Predict Benefit From a Novel Treatment for Vertical Heterophoria
Conditions: Binocular Vision Dysfunction;   Vertical Heterophoria
Intervention: Other: Questionnaires and Optometrist Prism Challenge/Treatment
Outcome Measure: VH Diagnosis
8 Unknown  Effects of Prismatic Spectacle Lenses on Symptoms of Dizziness, Headache and Anxiety as Caused by Vertical Heterophoria
Conditions: Binocular Dysfunction;   Vertical Heterophoria;   Vision, Binocular;   Vision Disparity
Interventions: Device: Lenses containing prismatic correction;   Device: Lenses not containing prismatic correction
Outcome Measures: Evidence of change / improvement of symptoms of headache, dizziness and anxiety as demonstrated by validated, self-administered survey tools for these symptoms;   Evidence that a new survey tool developed by the authors to assess changes / improvement in dizziness, headache and anxiety associated with Vertical Heterophoria correlates to validated, self-administered survey tools for these same symptoms
9 Recruiting Effects of Dexmedetomidine Premedication on Emergence Agitation After Strabismus Surgery in Children
Conditions: Inhalational Anesthetics Adverse Reaction;   Delirium on Emergence;   Strabismus Following Ocular Surgery
Interventions: Drug: Dexmedetomidine;   Drug: Midazolam;   Drug: Saline
Outcome Measures: Emergence agitation;   Postoperative vomiting
10 Not yet recruiting Neurovascular Coupling in Subjects With Amblyopia
Conditions: Amblyopia ex Strabismus;   Amblyopia ex Anisometropia
Interventions: Device: Dynamic Vessel Analyzer;   Other: Laser Doppler Velocimetry;   Device: 7-Tesla MRI;   Other: Pattern electroretinography
Outcome Measures: Retinal Vessel Diameter in Response to Flickering Light (DVA);   Retinal (arterial and venous) oxygen saturation;   Retinal blood velocity in response to flickering light;   High resolution functional and anatomical imaging of the visual pathway;   Inner Retinal Function
11 Unknown  The Effect of Dexmedetomidine on Decreasing Emergence Agitation and Delirium in Pediatric Patients Undergoing Strabismus Surgery
Condition: Strabismus
Interventions: Drug: Dexmedetomidine;   Drug: placebo group
Outcome Measures: objective pain score;   pediatric anesthesia emergence delirium (PAED) scale;   5-point agitation scale
12 Recruiting Intranasal Dexmedetomidine vs Midazolam-ketamine Combination for Premedication of Pediatric Patients
Conditions: Premedication;   Oculocardiac Reflex
Interventions: Drug: Dexmedetomidine;   Drug: Ketamine
Outcome Measures: the efficacy of premedication on ramsey sedation score;   the effects of premedication on oculocardiac reflex;   mask acceptance scale;   the parenteral separation anxiety scale
13 Recruiting Study of Non-surgical Treatment Versus Observation in Asian Children With Intermittent Exotropia
Condition: Intermittent Exotropia
Intervention: Procedure: Non surgical therapy
Outcome Measure: Control of Strabismus
14 Not yet recruiting The Effect of Remifentanil Infusion During Emergence on the Incidence of Emergence Delirium
Condition: Delirium
Interventions: Drug: Remifentanil;   Drug: Placebo
Outcome Measures: the scale of emergence agitation;   the effect of remifentanil on the emergence
15 Recruiting Post-operative Cognitive Dysfunction and the Change of Regional Cerebral Oxygen Saturation in Elderly Patients Undergoing Spinal Surgery
Condition: Strabismus
Intervention: Other: Neurologic and neuropsychologic tests
Outcome Measures: K-MMSE;   visuomotor test(D-LOTCA battery);   Regional cerebral oxymetry monitoring
16 Unknown  The Effect of Vision Therapy/Orthoptic on Motor & Sensory Status of the 3 to 7 Years Old Strabismic Patients
Condition: Strabismus
Intervention: Other: vision therapy
Outcome Measure:
17 Recruiting Hyperopia Treatment Study 1 (HTS1)
Condition: Hyperopia
Intervention: Procedure: Glasses
Outcome Measures: Proportion of subjects with confirmation of failure criteria;   Best Visual Acuity;   Development of Strabismus;   Subgroup Analysis;   Observation Group Deterioration;   Development of Amblyopia;   Near Visual Acuity
18 Recruiting Early Versus Delayed Surgery for Infantile Esotropia
Condition: Esotropia
Interventions: Procedure: mVEP Testing;   Procedure: Stereoacuity Testing;   Procedure: Optokinetic nystagmus testing;   Procedure: Motion detection testing;   Procedure: Motion discrimination testing
Outcome Measures: Motion visual evoked potential (mVEPs) asymmetry;   Stereopsis;   Optokinetic nystagmus (OKN) asymmetry;   Global Motion Perception
19 Not yet recruiting ASIS for Enbrel in Plaque Psoriasis
Condition: Plaque Psoriasis.
Interventions: Drug: Gadolinium;   Drug: Efficacy of Enbrel subcutaneously at Week 12;   Drug: Efficacy of Enbrel subcutaneously at Week 24;   Drug: Efficacy of Enbrel subcutaneously at Week 36;   Drug: Efficacy of Enbrel subdermally at Week 12;   Drug: Efficacy of Enbrel subdermally at Week 24;   Drug: Efficacy of Enbrel subdermally at Week 36;   Drug: PASI 75 n(%) subcutaneously at Week 12;   Drug: PASI 75 n(%) subcutaneously at Week 24;   Drug: PASI 75 n(%) subcutaneously at Week 36;   Drug: PASI 75 n(%) subdermally at Week 12;   Drug: PASI 75 n(%) subdermally at Week 24;   Drug: PASI 75 n(%) subdermally at Week 36;   Drug: Adverse Reactions of Enbrel subcutaneously;   Drug: Adverse Reactions of Enbrel subdermally at Week 36
Outcome Measures: Relative Prolongation Ability Score for Gadolinium subdermally injected.;   Efficacy of Enbrel subcutaneously vs. subdermally in Plaque Psoriasis.
20 Recruiting Repository for Inherited Eye Diseases
Conditions: Retinitis Pigmentosa;   Inherited Ophthalmic Diseases
Intervention:
Outcome Measure:

These studies may lead to new treatments and are adding insight into Strabismus etiology and treatment.

A major focus of Strabismus research is the development of new drugs and other treatment options. Studies seek to identify new drugs to treat various related disorders and to find safer, more effective doses for medications already being used. Other research is aimed at identifying receptors or drug targets.


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