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Stress Medical Research Studies

Up-to-date List of Stress Medical Research Studies

What Research is Being Done?

A clinical study involves research using human volunteers (also called participants) that is intended to add to medical knowledge. There are two main types of clinical studies: clinical trials (also called interventional studies) and observational studies. Following list includes both interventional and observational studies.

Latest Stress Medical Research Studies

Rank Status Study
1 Not yet recruiting Endothelin Receptor Function and Acute Stress
Condition: Hypertension
Interventions: Drug: Bosentan;   Drug: Placebo
Outcome Measures: Flow-Mediated Dilation (FMD);   Arterial Stiffness Evaluation (PWV);   Physio Flow;   Femoral blood flow;   Blood Pressure
2 Unknown  Steroid-induced Reduction of Surgical Stress Study
Conditions: Coronary Artery Stenosis;   Coronary Artery Bypass Graft Surgery
Interventions: Drug: Dexamethasone;   Drug: Placebo
Outcome Measures: Expression of p38 in cultured cells and cardiac tissue;   Pro-apoptotic signaling, precursor peptides of ANP (proANP), vasopressin (Copeptin), proET-1 and Adrenomedullin (proADM). Age, gender, length, body weight, hematocrit, Hb, leukocytes, surgery time, clamp time, CPB time
3 Not yet recruiting Stress Resilience Training System
Conditions: Perceived Stress;   Sleep Quality;   Anxiety;   Performance;   Depression;   PTSD
Interventions: Behavioral: Stress Resilience Training System (SRTS);   Behavioral: Progressive Muscle Relaxation (PMR);   Behavioral: Wait-list control
Outcome Measures: Perceived Stress Scale-10;   Pittsburgh Sleep Quality Index (PSQI);   Generalized Anxiety Disorder Measure (GAD-7);   PTSD Checklist -Civilian Version (PCL-C);   Patient Health Questionnaire (PHQ-9);   Response to Stressful Experiences Scale (RSES);   Brief COPE;   Unit Support;   Quality of Life Scale (QOLS);   Performance Indicator;   Attrition Rate
4 Not yet recruiting Effects of Mindfulness Meditation and Stress Management Training on Perceived Stress, Psychological Well-being, and Sleep Quality Among Patients Diagnosed With Breast Cancer
Condition: Breast Cancer
Interventions: Behavioral: Mindfulness-based Stress reduction;   Behavioral: Expressive writing condition
Outcome Measures: Change in Perceived Stress;   Change in Psychological Well-Being;   Change in Sleep quality;   Change in Perceived Stress;   Change in Psychological well-being
5 Recruiting Myocardial Infarction - Stress Prevention Intervention
Conditions: Stress Disorders, Post-Traumatic;   Myocardial Infarction
Interventions: Behavioral: Minimal behavioral intervention;   Behavioral: Control intervention
Outcome Measures: Clinician-rated posttraumatic Stress level;   Self-rated Posttraumatic Stress;   Quality of Life;   Depressive Symptoms;   Overall psychological diStress;   Positive and Negative Affect;   Time duration to recurrence at previous job (incl. part-time);   Time duration to recurrence at household to extent at least 50%;   Vitality status;   Recurrent Hospitalisations;   Recurrent Doctor Visits - general practitioner as well as specialist;   Inflammation Markers;   Hemostasis Markers;   Metabolic Factors;   Anthropometric measurements;   Resting hemodynamics;   Heart rate variability;   Stress Hormones
6 Recruiting Descriptive Study of Biological Stress and Perceived Stress at the Center 15
Conditions: Physiological Stress;   Psychological Stress
Intervention: Other: salivary sampling by a biomnis swab
Outcome Measures: biological Stress by salivary cortisol secretion;   perceived Stress : VAS and SPPN questionnaire
7 Not yet recruiting Nitric Oxide Bioavailability and Early Life Stress (NO-Stress)
Condition: Cardiovascular Disease
Interventions: Dietary Supplement: Antioxidant cocktail;   Other: Biopsy;   Other: Placebo;   Drug: NMD; 0.4mg sub-lingual nitroglycerin spray
Outcome Measures: Acute Change in Flow mediated dilation;   Acute Change in Biomarkers of oxidative Stress;   Acute Change in Arterial Stiffness;   Acute change in Flow mediated dilation
8 Not yet recruiting CO2 as a Stress Agent for Perfusion Imaging
Condition: Coronary Artery Disease
Interventions: Device: Delivery of precise levels of carbon dioxide with the RespirAct™ Gen3 sequential gas delivery system;   Device: Delivery of rubidium radioisotope (Rb-82) using the automated pump/elution system
Outcome Measures: Myocardial blood flow differences;   Absolute myocardial blood flow differences between end-tidal CO2 scans;   Difference bewteen absolute myocardial blood flow with hypercapnia and with adenosine Stress.
9 Recruiting Stress Reactivity in Veterans Receiving Pharmacological Treatment for PTSD and Alcohol Dependence
Conditions: Post-traumatic Stress Disorder;   Alcohol Dependence
Intervention: Behavioral: Stress
Outcome Measures: Anxiety, craving for alcohol and hormone levels;   treatment efficacy
10 Recruiting Stress Reduction for Overweight or Obese Women Either With Polycystic Ovary Syndrome (PCOS) or Without PCOS (Non-PCOS)
Conditions: Polycystic Ovary Syndrome;   Overweight;   Obesity;   Stress, Physiological;   Stress, Psychological
Interventions: Behavioral: Stress reduction;   Behavioral: Stress reduction with Health education
Outcome Measures: Change from Baseline in Toronto Mindfulness Scale at 8 weeks;   Change from Baseline in Toronto Mindfulness Scale at 16 weeks;   Change from Baseline in Hemoglobin A1c at 8 weeks;   Change from Baseline in Hemoglobin A1c at 16 weeks;   Change from Baseline in Mean Arterial Pressure at 8 weeks;   Change from Baseline in Mean Arterial Pressure at 16 weeks;   Change from Baseline in SF-36 at 8 weeks;   Change from Baseline in SF-36 at 16 weeks;   Change from Baseline in Brief Symptom Inventory-18 at 8 weeks;   Change from Baseline in Brief Symptom Inventory-18 at 16 weeks
11 Recruiting Stress Management Intervention for Mothers of Children With Cancer
Conditions: Stress;   Depression
Intervention: Behavioral: Stress management
Outcome Measure: change in Maternal depression is being assessed, the Beck Depression Inventory ( BDI), the Perceived Stress Scale (PSS) and other measures assessing maternal depression will be used
12 Recruiting Stress Management for Cancer Patients: How Well Does it Work? (C2H-D)
Conditions: Mood;   Stress, Psychological
Intervention: Behavioral: From Cancer to Health (C2H-D)
Outcome Measures: Change from baseline to post-intensive intervention assessment in mood on the 65-item Profile of Mood States (POMS);   Change from baseline to post-intensive intervention assessment in cancer-specific Stress on the 20-item Impact of Events Scale (IES);   Change from baseline to post-intensive intervention assessment in social support using the 20 item Perceived Social Support from Your Family Scale (PSS-Fa);   Change from baseline to post-intensive intervention assessment in physical activity on the 3-item Physical Activity Rating Scale (PAR);   Change from baseline to post-intensive intervention assessment in diet on the 23-item Food Habits Questionnaire (FHQ);   Change from baseline to post-intensive intervention assessment in sexual health on the 4-item Your Sexual Life questionnaire
13 Recruiting Effects of Different Types of Anesthesia on Stress Response in Laparoscopic Gastric Bypass for Type 2 Diabetes Mellitus
Conditions: Diabetes;   Stress;   Anesthesia
Interventions: Other: different types of anesthesia;   Drug: Dexmedetomidine
Outcome Measures: Stress Indicators;   Vital Signs
14 Recruiting Neural Correlates of Stress Reduction
Conditions: Stress;   Psychological Stress;   Life Stress;   Emotional Stress;   Social Stress
Intervention: Behavioral: Stress Reduction
Outcome Measures: Changes in gray matter structure;   Emotion regulation
15 Unknown  Stress Adenosine Cardiac Magnetic Resonance (MR) Comparison With Single Photon Emission Computed Tomography (SPECT) Imaging
Conditions: Coronary Artery Disease;   Cardiac Perfusion
Interventions: Procedure: SPECT Imaging;   Procedure: Stress Adenosine CMR
Outcome Measure: Stress adenosine cardiac MRIis not inferior to SPECT imaging in diagnosing myocardial ischemia
16 Recruiting Mindful Hearts Study
Conditions: Cardiovascular Disease;   Psychological Stress;   Stroke;   Coronary Artery Disease
Interventions: Behavioral: Mindfulness Based Stress Reduction;   Behavioral: Health Education Program
Outcome Measures: Psychological Stress;   Cardiovascular Risk
17 Unknown  Stress Management Intervention in Inner City Adolescents With Asthma
Conditions: Asthma;   Psychosocial Stress
Interventions: Behavioral: Stress management program;   Other: Peer viewed movies
Outcome Measures: Scope of change in perceived Stress from enrollment to completion of study using the Perceived Stress scale;   Secondary outcomes within scope of change from enrollment to completion of study in coping as assessed by Kidcope;   Secondary outcomes within scope of change from enrollment to completion of study in anxiety as measured by State Trait Inventory;   Secondary outcomes within scope of change from enrollment to completion of study in quality of life as assessed by PAQLQ
18 Recruiting Stress Echocardiography and Heart Computed Tomography (CT) Scan in Emergency Department Patients With Chest Pain
Conditions: Chest Pain;   Angina;   Angina Pectoris;   Coronary Artery Disease
Interventions: Procedure: Stress Echocardiography;   Procedure: Coronary CT Angiography
Outcome Measures: Hospital admission;   Emergency Department length of stay;   Hospital length of stay;   Estimated cost of initial care;   Repeat visits to the Emergency Department;   Death;   Non-fatal myocardial infarction
19 Recruiting The Effects of Physical Training on Physiological and Psychological Stress-reactions and Cognitive Function.
Condition: Healthy Sedentary Individuals
Intervention: Other: Exercise
Outcome Measures: Cortisol responses to acute psychosocial Stress.;   Cognitive function;   Self-reported Stress sensitivity and symptoms;   Adrenocorticotropic hormone (ACTH) response to psychosocial Stress;   Dehydroepiandrostreone (DHEA) and dehydroepiandrosterone sulfate (DHEAS) response to psychosocial Stress
20 Recruiting Developing Field Tools for Real-Time Assessment of Exposure to Psychosocial Stress and Drug Use in an Outpatient Treatment Population
Conditions: Psychological Stress;   Drug Abuse
Outcome Measures: Real time self reported drug use and psychological Stress.;   Biological indices of drug use and psychological Stress: retrospective self-reports of drug use and psychosocial Stress.

These studies may lead to new treatments and are adding insight into Stress etiology and treatment.

A major focus of Stress research is the development of new drugs and other treatment options. Studies seek to identify new drugs to treat various related disorders and to find safer, more effective doses for medications already being used. Other research is aimed at identifying receptors or drug targets.

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